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SARS-CoV-2 Spike Proteins

(SARS-CoV-2 Spike (SARS-CoV-2 S))
mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.

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  • Target: SARS-CoV-2 Spike (SARS-CoV-2 S)
  • Protein
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN7825137
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, B.1.617.2 - delta, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Mammalian Cells
$485.29 View price
  • 100 μg
Delivery in 12 to 15 Business Days Shipping to: United States
ABIN7825132
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 14-1208, Trimer) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Mammalian Cells
$485.29 View price
  • 100 μg
Delivery in 12 to 15 Business Days Shipping to: United States
ABIN7825135
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Mammalian Cells
$485.29 View price
  • 100 μg
Delivery in 12 to 15 Business Days Shipping to: United States
ABIN7825134
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, B.1.351 - beta, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Mammalian Cells
$485.29 View price
  • 100 μg
Delivery in 12 to 15 Business Days Shipping to: United States
ABIN7825133
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 14-1208, Trimer) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Mammalian Cells
$485.29 View price
  • 100 μg
Delivery in 12 to 15 Business Days Shipping to: United States
ABIN7825130
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 14-1208, Trimer) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Mammalian Cells
$485.29 View price
  • 100 μg
Delivery in 12 to 15 Business Days Shipping to: United States
ABIN7825131
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 14-1208, Trimer) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Mammalian Cells
$485.29 View price
  • 100 μg
Delivery in 12 to 15 Business Days Shipping to: United States
ABIN7890292
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-532, RBD) (Fc Tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
$518.54 View price
  • 100 μg
Delivery in 4 to 5 Business Days Shipping to: United States
ABIN7890298
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-589, RBD) (mFc Tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Human Cells
$3,429.14 View price
  • 1 mg
Delivery in 11 to 22 Business Days Shipping to: United States
ABIN7890299
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-591, RBD, SD1) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Human Cells
$3,429.14 View price
  • 1 mg
Delivery in 11 to 22 Business Days Shipping to: United States
ABIN7890297
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 331-524, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Human Cells
$2,421.98 View price
  • 1 mg
Delivery in 11 to 22 Business Days Shipping to: United States
ABIN7890304
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (mFc Tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Human Cells
$2,421.98 View price
  • 1 mg
Delivery in 11 to 22 Business Days Shipping to: United States
ABIN7890303
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-591, RBD, W436R) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Human Cells
$2,882.82 View price
  • 1 mg
Delivery in 11 to 22 Business Days Shipping to: United States
ABIN7890305
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Human Cells
$2,421.98 View price
  • 1 mg
Delivery in 11 to 22 Business Days Shipping to: United States
ABIN7890308
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD, V367F) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Human Cells
$2,882.82 View price
  • 1 mg
Delivery in 11 to 22 Business Days Shipping to: United States
ABIN7890309
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, R408I, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Human Cells
$2,882.82 View price
  • 1 mg
Delivery in 11 to 22 Business Days Shipping to: United States
ABIN7890314
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, D364Y, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Human Cells
$2,882.82 View price
  • 1 mg
Delivery in 11 to 22 Business Days Shipping to: United States
ABIN7890315
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD, V341I) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Human Cells
$2,882.82 View price
  • 1 mg
Delivery in 11 to 22 Business Days Shipping to: United States
ABIN7890294
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-532, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Insect Cells
$518.54 View price
  • 100 μg
Delivery in 4 to 5 Business Days Shipping to: United States
ABIN7890296
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 331-524, RBD) (mFc Tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Human Cells
$2,421.98 View price
  • 1 mg
Delivery in 11 to 22 Business Days Shipping to: United States
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Mammalian Cells
Protein Type
Recombinant
Purity
>90 % as determined by SDS-PAGE.
Catalog No. ABIN7825137
$485.29
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 15 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Mammalian Cells
Protein Type
Recombinant
Purity
>90 % as determined by SDS-PAGE.
Catalog No. ABIN7825132
$485.29
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 15 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Mammalian Cells
Protein Type
Recombinant
Purity
>90 % as determined by SDS-PAGE.
Catalog No. ABIN7825135
$485.29
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 15 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Mammalian Cells
Protein Type
Recombinant
Purity
>90 % as determined by SDS-PAGE.
Catalog No. ABIN7825134
$485.29
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 15 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Mammalian Cells
Protein Type
Recombinant
Purity
>90 % as determined by SDS-PAGE.
Catalog No. ABIN7825133
$485.29
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 15 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Mammalian Cells
Protein Type
Recombinant
Purity
>90 % as determined by SDS-PAGE.
Catalog No. ABIN7825130
$485.29
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 15 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Mammalian Cells
Protein Type
Recombinant
Purity
>90 % as determined by SDS-PAGE.
Catalog No. ABIN7825131
$485.29
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 12 to 15 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
HEK-293 Cells
Protein Type
Recombinant
Catalog No. ABIN7890292
$518.54
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 4 to 5 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Human Cells
Protein Type
Recombinant
Catalog No. ABIN7890298
$3,429.14
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to: United States
Delivery in 11 to 22 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Human Cells
Protein Type
Recombinant
Catalog No. ABIN7890299
$3,429.14
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to: United States
Delivery in 11 to 22 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Human Cells
Protein Type
Recombinant
Catalog No. ABIN7890297
$2,421.98
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to: United States
Delivery in 11 to 22 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Human Cells
Protein Type
Recombinant
Catalog No. ABIN7890304
$2,421.98
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to: United States
Delivery in 11 to 22 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Human Cells
Protein Type
Recombinant
Catalog No. ABIN7890303
$2,882.82
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to: United States
Delivery in 11 to 22 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Human Cells
Protein Type
Recombinant
Catalog No. ABIN7890305
$2,421.98
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to: United States
Delivery in 11 to 22 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Human Cells
Protein Type
Recombinant
Catalog No. ABIN7890308
$2,882.82
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to: United States
Delivery in 11 to 22 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Human Cells
Protein Type
Recombinant
Catalog No. ABIN7890309
$2,882.82
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to: United States
Delivery in 11 to 22 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Human Cells
Protein Type
Recombinant
Catalog No. ABIN7890314
$2,882.82
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to: United States
Delivery in 11 to 22 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Human Cells
Protein Type
Recombinant
Catalog No. ABIN7890315
$2,882.82
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to: United States
Delivery in 11 to 22 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Insect Cells
Protein Type
Recombinant
Catalog No. ABIN7890294
$518.54
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 4 to 5 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Human Cells
Protein Type
Recombinant
Catalog No. ABIN7890296
$2,421.98
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to: United States
Delivery in 11 to 22 Business Days

Latest Publications for our SARS-CoV-2 Spike Proteins

Gao, Yang, Dong, Tang, Cao, Ding, Zhu, Bai, Xia, Zhu, Zhao, Peng, Xu, Zhang: "A multi-antigen vaccinia vaccine broadly protected mice against SARS-CoV-2 and influenza A virus while also targeting SARS-CoV-1 and MERS-CoV." in: Frontiers in immunology, Vol. 15, pp. 1473428, (2024) (PubMed).

Yang, Liu, Jiang, Zhang, Fu, Li, Hu, Yuan: "Antibodies against SARS-CoV-2 non-structural protein 3 cross-react with human muscle cells and neuroglial cells." in: Vaccine, Vol. 42, Issue 6, pp. 1259-1267, (2024) (PubMed).

Mazunina, Gushchin, Bykonia, Kleymenov, Siniavin, Kozlova, Mukasheva, Shidlovskaya, Kuznetsova, Usachev, Zlobin, Burtseva, Ivanov, Logunov, Gintsburg: "Immunogenicity and Efficacy of Combined mRNA Vaccine Against Influenza and SARS-CoV-2 in Mice Animal Models." in: Vaccines, Vol. 12, Issue 11, (2024) (PubMed).

Wu, Cong, Wei, Hu, Sun, Ran, Liao, Zheng, Ye: "A Naïve Phage Display Library-Derived Nanobody Neutralizes SARS-CoV-2 and Three Variants of Concern." in: International journal of nanomedicine, Vol. 18, pp. 5781-5795, (2023) (PubMed).

Payam, Funari, Scamarcio, Bhalla: "Sensing Dynamically Evolved Short-Range Nanomechanical Forces in Fast-Mutating Single Viral Spike Proteins." in: Small science, Vol. 3, Issue 8, pp. 2300029, (2023) (PubMed).

Erickson, Logsdon, Rhea, Hansen, Holden, Banks, Smith, German, Farr, Morley, Weaver, Hirsch, Kovac, Kontsekova, Baumann, Omer, Raber: "Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease." in: Brain, behavior, and immunity, Vol. 109, pp. 251-268, (2023) (PubMed).

Meng, Zha, Zhou, Cao, Jiang, Zhu, Li, Lu, Zhang, Yang, Feng, Gu, Tang, Jiang, Li, Lavillette, Zhang: "A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy." in: PLoS pathogens, Vol. 19, Issue 1, pp. e1011085, (2023) (PubMed).

Bohnacker, Hartung, Henkel, Quaranta, Kolmert, Priller, Ud-Dean, Giglberger, Kugler, Pechtold, Yazici, Lechner, Erber, Protzer, Lingor, Knolle, Chaker, Schmidt-Weber, Wheelock, Esser-von Bieren: "Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages." in: Mucosal immunology, Vol. 15, Issue 3, pp. 515-524, (2022) (PubMed).

Bhalla, Payam, Morelli, Sharma, Johnson, Thomson, Jolly, Canfarotta: "Nanoplasmonic biosensor for rapid detection of multiple viral variants in human serum." in: Sensors and actuators. B, Chemical, Vol. 365, pp. 131906, (2022) (PubMed).

Vogt, Augusto, Martina, Chang, Nasrallah, Speiser, Vogel, Bachmann, Mohsen: "Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron." in: Vaccines, Vol. 10, Issue 5, (2022) (PubMed).

Aliases for SARS-CoV-2 Spike Proteins

E2 glycoprotein precursor (S) Proteins
Surface Glycoprotein (S) Proteins
E2 Proteins
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