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SARS-CoV-2 Spike Proteins

(SARS-CoV-2 Spike (SARS-CoV-2 S))
mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.

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  • Target: SARS-CoV-2 Spike (SARS-CoV-2 S)
  • Protein
Catalog no. Product Reactivity Host / Clonality Application Price & lead time
ABIN7454347
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, BA.2.75 - Omicron, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
$484.42 View price
  • 100 μg
  • 500 μg
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN7454349
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, BA.4.6 - Omicron, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
$484.42 View price
  • 100 μg
  • 500 μg
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN7454351
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD, XBB - Omicron, XBB.1.5 - Omicron) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
$484.42 View price
  • 100 μg
  • 500 μg
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN7454350
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
$484.42 View price
  • 100 μg
  • 500 μg
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN7454352
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD, XBB - Omicron) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
$484.42 View price
  • 100 μg
  • 500 μg
Delivery in 11 to 14 Business Days Shipping to: United States
ABIN7665353
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, BA.4 - Omicron, Receptor Binding Domain) (His tag) SARS-CoV-2 S · Protein Coronavirus (CoV) HEK-293 Cells
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
$757.23 View price
  • 50 μg
  • 1 mg
  • 200 μg
Delivery in 15 to 20 Business Days Shipping to: United States
ABIN7665352
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 16-1213) (His-Avi Tag) SARS-CoV-2 S · Protein Coronavirus (CoV) HEK-293 Cells
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
$658.46 View price
  • 50 μg
  • 1 mg
  • 200 μg
Delivery in 15 to 20 Business Days Shipping to: United States
ABIN6961041
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, N501Y, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
$324.50 View price
  • 50 μg
  • 1 mg
  • 500 μg
Delivery in 11 to 22 Business Days Shipping to: United States
ABIN6961042
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, N501Y, RBD) (Fc Tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
$324.50 View price
  • 50 μg
  • 1 mg
  • 500 μg
Delivery in 11 to 22 Business Days Shipping to: United States
ABIN7884571
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.617.2 - delta, Trimer) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • WB (Western Blotting: Listed application)
$953.53 View price
  • 100 μg
Delivery in 10 to 15 Business Days Shipping to: United States
ABIN7884575
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.617.2 - delta, RBD) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
$1,004.15 View price
  • 100 μg
Delivery in 10 to 15 Business Days Shipping to: United States
ABIN7385980
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Insect Cells
  • WB (Western Blotting: Listed application)
  • EIA (Enzyme Immunoassay: Listed application)
$1,954.26 View price
  • 1 mg
Delivery in 3 to 5 Business Days Shipping to: United States
ABIN7884570
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (Trimer) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • WB (Western Blotting: Listed application)
$953.53 View price
  • 100 μg
Delivery in 10 to 15 Business Days Shipping to: United States
ABIN7884567
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (Subunit S1) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Escherichia coli (E. coli)
  • WB (Western Blotting: Listed application)
$747.35 View price
  • 100 μg
Delivery in 10 to 15 Business Days Shipping to: United States
ABIN7884568
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) Escherichia coli (E. coli)
  • WB (Western Blotting: Listed application)
$747.35 View price
  • 100 μg
Delivery in 10 to 15 Business Days Shipping to: United States
ABIN7884569
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) CHO Cells
  • WB (Western Blotting: Listed application)
$391.78 View price
  • 5 μg
Delivery in 10 to 15 Business Days Shipping to: United States
ABIN7884573
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (B.1.1.529 - Omicron, Trimer) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
$1,152.30 View price
  • 100 μg
Delivery in 10 to 15 Business Days Shipping to: United States
ABIN7669698
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (mFc Tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • ELISA (ELISA: Listed application)
  • BLI (Bio-Layer Interferometry: Listed application)
$1,029.34 View price
  • 100 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7669683
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, G476S, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
  • ELISA (ELISA: Listed application)
$1,029.34 View price
  • 100 μg
Delivery in 11 to 15 Business Days Shipping to: United States
ABIN7669629
SARS-CoV-2 Spike Protein (SARS-CoV-2 S) (AA 319-541, RBD) (His tag) SARS-CoV-2 S · Protein SARS Coronavirus-2 (SARS-CoV-2) HEK-293 Cells
$1,029.34 View price
  • 100 μg
Delivery in 11 to 15 Business Days Shipping to: United States
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Biological Activity
Active
Catalog No. ABIN7454347
$484.42
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Biological Activity
Active
Catalog No. ABIN7454349
$484.42
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Biological Activity
Active
Catalog No. ABIN7454351
$484.42
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Biological Activity
Active
Catalog No. ABIN7454350
$484.42
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC
Biological Activity
Active
Catalog No. ABIN7454352
$484.42
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
Protein
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
Origin
Coronavirus (CoV)
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
Greater than 90 % as determined by SDS-PAGE.
Catalog No. ABIN7665353
$757.23
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 20 Business Days
Protein
  • ELISA (ELISA: Listed application)
  • WB (Western Blotting: Listed application)
Origin
Coronavirus (CoV)
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
Greater than 90 % as determined by SDS-PAGE.
Biological Activity
Active
Catalog No. ABIN7665352
$658.46
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 20 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
HEK-293 Cells
Protein Type
Recombinant
Catalog No. ABIN6961041
$324.50
Plus shipping costs $50.00, if applicable $20.00 dry ice
50 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 22 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
HEK-293 Cells
Protein Type
Recombinant
Catalog No. ABIN6961042
$324.50
Plus shipping costs $50.00, if applicable $20.00 dry ice
50 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 22 Business Days
Protein
  • WB (Western Blotting: Listed application)
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
>95 %
Catalog No. ABIN7884571
$953.53
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 10 to 15 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
HEK-293 Cells
Protein Type
Recombinant
Catalog No. ABIN7884575
$1,004.15
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 10 to 15 Business Days
Protein
  • WB (Western Blotting: Listed application)
  • EIA (Enzyme Immunoassay: Listed application)
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Insect Cells
Protein Type
Recombinant
Catalog No. ABIN7385980
$1,954.26
Plus shipping costs $50.00, if applicable $20.00 dry ice
1 mg
Shipping to: United States
Delivery in 3 to 5 Business Days
Protein
  • WB (Western Blotting: Listed application)
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
>95 %
Catalog No. ABIN7884570
$953.53
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 10 to 15 Business Days
Protein
  • WB (Western Blotting: Listed application)
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
>98 %
Catalog No. ABIN7884567
$747.35
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 10 to 15 Business Days
Protein
  • WB (Western Blotting: Listed application)
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
Escherichia coli (E. coli)
Protein Type
Recombinant
Purity
>98 %
Catalog No. ABIN7884568
$747.35
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 10 to 15 Business Days
Protein
  • WB (Western Blotting: Listed application)
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
CHO Cells
Protein Type
Recombinant
Purity
>98 %
Catalog No. ABIN7884569
$391.78
Plus shipping costs $50.00
5 μg
Shipping to: United States
Delivery in 10 to 15 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
>90 %
Catalog No. ABIN7884573
$1,152.30
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 10 to 15 Business Days
Protein
  • ELISA (ELISA: Listed application)
  • BLI (Bio-Layer Interferometry: Listed application)
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by reducing SDS-PAGE.
Biological Activity
Active
Catalog No. ABIN7669698
$1,029.34
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
  • ELISA (ELISA: Listed application)
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 95 % as determined by reducing SDS-PAGE.
Biological Activity
Active
Catalog No. ABIN7669683
$1,029.34
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 15 Business Days
Protein
Origin
SARS Coronavirus-2 (SARS-CoV-2)
Host
HEK-293 Cells
Protein Type
Recombinant
Purity
> 85 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7669629
$1,029.34
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 15 Business Days

Latest Publications for our SARS-CoV-2 Spike Proteins

Gao, Yang, Dong, Tang, Cao, Ding, Zhu, Bai, Xia, Zhu, Zhao, Peng, Xu, Zhang: "A multi-antigen vaccinia vaccine broadly protected mice against SARS-CoV-2 and influenza A virus while also targeting SARS-CoV-1 and MERS-CoV." in: Frontiers in immunology, Vol. 15, pp. 1473428, (2024) (PubMed).

Yang, Liu, Jiang, Zhang, Fu, Li, Hu, Yuan: "Antibodies against SARS-CoV-2 non-structural protein 3 cross-react with human muscle cells and neuroglial cells." in: Vaccine, Vol. 42, Issue 6, pp. 1259-1267, (2024) (PubMed).

Mazunina, Gushchin, Bykonia, Kleymenov, Siniavin, Kozlova, Mukasheva, Shidlovskaya, Kuznetsova, Usachev, Zlobin, Burtseva, Ivanov, Logunov, Gintsburg: "Immunogenicity and Efficacy of Combined mRNA Vaccine Against Influenza and SARS-CoV-2 in Mice Animal Models." in: Vaccines, Vol. 12, Issue 11, (2024) (PubMed).

Wu, Cong, Wei, Hu, Sun, Ran, Liao, Zheng, Ye: "A Naïve Phage Display Library-Derived Nanobody Neutralizes SARS-CoV-2 and Three Variants of Concern." in: International journal of nanomedicine, Vol. 18, pp. 5781-5795, (2023) (PubMed).

Payam, Funari, Scamarcio, Bhalla: "Sensing Dynamically Evolved Short-Range Nanomechanical Forces in Fast-Mutating Single Viral Spike Proteins." in: Small science, Vol. 3, Issue 8, pp. 2300029, (2023) (PubMed).

Erickson, Logsdon, Rhea, Hansen, Holden, Banks, Smith, German, Farr, Morley, Weaver, Hirsch, Kovac, Kontsekova, Baumann, Omer, Raber: "Blood-brain barrier penetration of non-replicating SARS-CoV-2 and S1 variants of concern induce neuroinflammation which is accentuated in a mouse model of Alzheimer's disease." in: Brain, behavior, and immunity, Vol. 109, pp. 251-268, (2023) (PubMed).

Meng, Zha, Zhou, Cao, Jiang, Zhu, Li, Lu, Zhang, Yang, Feng, Gu, Tang, Jiang, Li, Lavillette, Zhang: "A Spike-destructing human antibody effectively neutralizes Omicron-included SARS-CoV-2 variants with therapeutic efficacy." in: PLoS pathogens, Vol. 19, Issue 1, pp. e1011085, (2023) (PubMed).

Bohnacker, Hartung, Henkel, Quaranta, Kolmert, Priller, Ud-Dean, Giglberger, Kugler, Pechtold, Yazici, Lechner, Erber, Protzer, Lingor, Knolle, Chaker, Schmidt-Weber, Wheelock, Esser-von Bieren: "Mild COVID-19 imprints a long-term inflammatory eicosanoid- and chemokine memory in monocyte-derived macrophages." in: Mucosal immunology, Vol. 15, Issue 3, pp. 515-524, (2022) (PubMed).

Bhalla, Payam, Morelli, Sharma, Johnson, Thomson, Jolly, Canfarotta: "Nanoplasmonic biosensor for rapid detection of multiple viral variants in human serum." in: Sensors and actuators. B, Chemical, Vol. 365, pp. 131906, (2022) (PubMed).

Vogt, Augusto, Martina, Chang, Nasrallah, Speiser, Vogel, Bachmann, Mohsen: "Increased Receptor Affinity and Reduced Recognition by Specific Antibodies Contribute to Immune Escape of SARS-CoV-2 Variant Omicron." in: Vaccines, Vol. 10, Issue 5, (2022) (PubMed).

Aliases for SARS-CoV-2 Spike Proteins

E2 glycoprotein precursor (S) Proteins
Surface Glycoprotein (S) Proteins
E2 Proteins
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