anti-Human GRIN1 antibody for Flow Cytometry

Recommended GRIN1 Antibody (supplied by: Log in to see )

Antigen
Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) Antibodies
  • GluN1
  • MRD8
  • NMDA1
  • NMDAR1
  • NR1
  • nmda1
  • nmdar1
  • GB19253
  • GRIN1
  • NMD-R1
  • GluRdelta1
  • GluRzeta1
  • M100174
  • Nmdar
  • Rgsc174
  • NMDAR1.1
  • zgc:152678
  • glutamate ionotropic receptor NMDA type subunit 1
  • glutamate receptor, ionotropic, N-methyl D-aspartate 1 S homeolog
  • NMDA receptor 1
  • glutamate receptor, ionotropic, NMDA1 (zeta 1)
  • glutamate receptor, ionotropic, N-methyl D-aspartate 1a
  • GRIN1
  • grin1.S
  • grin1
  • Grin1
  • Nmdar1
  • grin1a
Epitope
AA 900-950
43
34
32
22
18
15
15
11
11
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus), Human
244
243
190
14
5
5
4
3
3
2
2
2
1
1
Host
Rabbit
241
52
13
Clonality
Polyclonal
Conjugate
This GRIN1 antibody is un-conjugated
7
7
6
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
231
149
89
40
36
24
22
14
10
9
2
2
1
1
Options
Supplier
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Available images

Catalog No. ABIN2017602
$ 280.57
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
6.840845 ABIN5952549 FACS ICC IF IHC IHC (p) WB Rabbit IgG C-Term Log in to see JM11-26 0

General

Antigen Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) Antibodies
Epitope AA 900-950
(43), (34), (32), (22), (18), (15), (15), (11), (11), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine), Rat (Rattus), Human
(244), (243), (190), (14), (5), (5), (4), (3), (3), (2), (2), (2), (1), (1)
Host Rabbit
(241), (52), (13)
Clonality
Polyclonal
Conjugate This GRIN1 antibody is un-conjugated
(7), (7), (6), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application Flow Cytometry (FACS), Western Blotting (WB)
(231), (149), (89), (40), (36), (24), (22), (14), (10), (9), (2), (2), (1), (1)
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Product Details anti-GRIN1 Antibody

Target Details GRIN1 Application Details Handling Images
Specificity NMDAR1 Antibody detects endogenous levels of mouse NMDAR1. It is predicted to react with human and rat NMDAR1 protein according to sequence homology.Positive Control: Mouse brain
Cross-Reactivity (Details) NMDAR1 Antibody detects endogenous levels of mouse NMDAR1. It is predicted to react with human and rat NMDAR1 protein according to sequence homology.Positive Control: Mouse brain
Purification Immunoaffinity chromatography
Immunogen KLH-coupled synthetic peptide within AA 900-950 of human NMDAR1
Isotype IgG2a
Plasmids, Primers & others

Target Details GRIN1

Product Details anti-GRIN1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name NMDAR1 (GRIN1 Antibody Abstract)
Background N-methyl-D-aspartate receptor (NMDAR) forms a heterodimer of at least one NMDAR1 and one NR2A-D subunit. NMDAR1 subunits and NR2 subunits bind to the co-agonist glycine and the neurotransmitter glutamate, respectively.'PKC'an phosphorylate NMDAR1 of the receptor at Ser890/Ser896, and PKA can phosphorylate NMDAR1 at Ser897. The phosphorylation of NMDAR1 by'PKC'ecreases its affinity for calmodulin, thus preventing the inhibitory effect of calmodulin on NMDAR. The phosphorylation of NMDAR1 by PKA probably counteracts the inhibitory effect of calcineurin on the receptor.
NMDAR1 Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 900-950 of human NMDAR1 (Swiss Prot: Q05586).
Pathways Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity

Application Details

Product Details anti-GRIN1 Antibody Target Details GRIN1 Handling Images back to top
Application Notes Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 0.5-1 µg/mLFlow cytometry: 1-3 µg for 1 x 106 cellsOther applications: user-optimized
Restrictions For Research Use only

Handling

Product Details anti-GRIN1 Antibody Target Details GRIN1 Application Details Images back to top
Format Lyophilized
Buffer PBS, pH 7.4, containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Storage 4 °C/-20 °C
Storage Comment The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Images

Product Details anti-GRIN1 Antibody Target Details GRIN1 Application Details Handling back to top
Supplier Images
Western Blotting (WB) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) (AA 900-950) antibody (ABIN2017602) Western blot analysis of tissue lysates using NMDAR1 Antibody (ABIN399084, 1 µg/mL) T...
Flow Cytometry (FACS) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 1 (GRIN1) (AA 900-950) antibody (ABIN2017602) Flow cytometric analysis of Ramos cells using NMDAR1 antibody, pAb, Rabbit (ABIN39908...