anti-Cow (Bovine) NMDAR2A antibody for Immunofluorescence

Recommended NMDAR2A Antibody

Antigen
Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) Antibodies
  • NMDAR2A
  • nr2a
  • GRIN2A
  • EPND
  • GluN2A
  • NR2A
  • glutamate ionotropic receptor NMDA type subunit 2A
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog
  • glutamate receptor ionotropic, NMDA 2A
  • glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • GRIN2A
  • grin2a.L
  • LOC100438553
  • Grin2a
Epitope
N-Term
118
56
27
19
17
15
10
9
8
8
8
8
7
5
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Mouse (Murine), Rat (Rattus)
271
218
217
6
4
3
2
2
1
1
1
Host
Rabbit
199
137
1
Clonality
Polyclonal
Conjugate
This NMDAR2A antibody is un-conjugated
21
17
15
12
10
10
8
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
265
206
76
66
59
43
33
26
20
18
3
2
2
2
Options
Catalog No. ABIN5551598
$ 511.50
Plus shipping costs $45.00

General

Antigen Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) Antibodies
Epitope N-Term
(118), (56), (27), (19), (17), (15), (10), (9), (8), (8), (8), (8), (7), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Mouse (Murine), Rat (Rattus)
(271), (218), (217), (6), (4), (3), (2), (2), (1), (1), (1)
Host Rabbit
(199), (137), (1)
Clonality
Polyclonal
Conjugate This NMDAR2A antibody is un-conjugated
(21), (17), (15), (12), (10), (10), (8), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(265), (206), (76), (66), (59), (43), (33), (26), (20), (18), (3), (2), (2), (2)
Supplier

Product Details anti-NMDAR2A Antibody

Target Details NMDAR2A Application Details Handling Images
Specificity This antibody recognizes the ~180k NR2A subunit of the NMDA Receptor.
Cross-Reactivity (Details) Species reactivity (expected):Bovine, Canine and Mouse.
Species reactivity (tested):Rat.
Purification Affinity Chromatography.
Immunogen Peptide from the N-terminus of the NR2A subunit of rat NMDA Receptor.
Isotype IgG
Plasmids, Primers & others

Target Details NMDAR2A

Product Details anti-NMDAR2A Antibody Application Details Handling Images back to top
Antigen
Alternative Name NMDA Receptor 2A (GRIN2A Antibody Abstract)
Background The ion channels activated by glutamate are typically divided into two classes. Glutamate receptors that are activated by kainate and alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as kainate/AMPA receptors (K/AMPAR). Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR). The NMDAR plays an essential role in memory, neuronal development and it has also been implicated in several disorders of the central nervous system including Alzheimer's, epilepsy and ischemic neuronal cell death (Grosshans et al., 2002, Wenthold et al., 2003, Carroll and Zukin, 2002). The NMDA receptor is also one of the principal molecular targets for alcohol in the CNS (Lovinger et al., 1989, Alvestad et al., 2003, Snell et al., 1996). The NMDAR is also potentiated by protein phosphorylation (Lu et al., 1999). The rat NMDAR1 (NR1) was the first subunit of the NMDAR to be cloned. The NR1 protein can form NMDA activated channels when expressed in Xenopus oocytes but the currents in such channels are much smaller than those seen in situ. Channels with more physiological characteristics are produced when the NR1 subunit is combined with one or more of the NMDAR2 (NR2 A-D) subunits.Synonyms: GRIN2A, Glutamate [NMDA] Receptor subunit epsilon-1, NMDAR2A, NR2A
Gene ID 2903
NCBI Accession NP_000824
UniProt Q12879
Pathways Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity

Application Details

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Handling Images back to top
Application Notes Western blot: 1/1000. Immunohistochemistry: 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Application Details Images back to top
Format Liquid
Buffer 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store the antibody undiluted (in aliquots) at-20 °C.