anti-Human NMDAR2A antibody for Enzyme Immunoassay

Recommended NMDAR2A Antibody

Antigen
Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) Antibodies
  • NMDAR2A
  • nr2a
  • GRIN2A
  • EPND
  • GluN2A
  • NR2A
  • glutamate ionotropic receptor NMDA type subunit 2A
  • glutamate receptor, ionotropic, N-methyl D-aspartate 2A L homeolog
  • glutamate receptor ionotropic, NMDA 2A
  • glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • GRIN2A
  • grin2a.L
  • LOC100438553
  • Grin2a
Epitope
AA 1298-1326, C-Term
118
57
26
19
17
15
9
9
8
8
7
7
7
5
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
270
219
217
7
4
3
2
2
1
1
1
Host
Rabbit
198
137
1
Clonality
Polyclonal
Conjugate
This NMDAR2A antibody is un-conjugated
21
17
15
12
10
10
8
6
6
6
6
6
6
6
6
6
6
6
6
6
6
6
4
2
2
2
2
2
2
2
2
2
2
2
2
2
2
Application
Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
264
205
76
67
59
43
32
26
19
18
3
3
2
1
Options

Available images

Catalog No. ABIN953719
$ 484.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Clonality References Details
7 ABIN953720 EIA IHC (p) WB Rabbit Ig Fraction AA 1064-1092, Middle Region Polyclonal 5

General

Antigen Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) Antibodies
Epitope AA 1298-1326, C-Term
(118), (57), (26), (19), (17), (15), (9), (9), (8), (8), (7), (7), (7), (5), (4), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human
(270), (219), (217), (7), (4), (3), (2), (2), (1), (1), (1)
Host Rabbit
(198), (137), (1)
Clonality
Polyclonal
Conjugate This NMDAR2A antibody is un-conjugated
(21), (17), (15), (12), (10), (10), (8), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application Enzyme Immunoassay (EIA), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(264), (205), (76), (67), (59), (43), (32), (26), (19), (18), (3), (3), (2), (1)
Pubmed 5 references available
Supplier

Product Details anti-NMDAR2A Antibody

Target Details NMDAR2A Application Details Handling References for anti-NMDAR2A antibody (ABIN953719) Images
Specificity This antibody recognizes Human NMDA Receptor 2A (C-term).
Purification Protein A column, followed by peptide affinity purification
Immunogen KLH conjugated synthetic peptide between 1298-1326 amino acids from the C-terminal region of Human NMDA Receptor 2A. Genename: GRIN2A
Isotype Ig Fraction
Plasmids, Primers & others

Target Details NMDAR2A

Product Details anti-NMDAR2A Antibody Application Details Handling References for anti-NMDAR2A antibody (ABIN953719) Images back to top
Antigen
Background N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: GRIN2A, Glutamate [NMDA] Receptor subunit epsilon-1, NMDAR2A, NR2A
Molecular Weight 165283 Da
Gene ID 2903
NCBI Accession NP_000824
Pathways Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity

Application Details

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Handling References for anti-NMDAR2A antibody (ABIN953719) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Application Details References for anti-NMDAR2A antibody (ABIN953719) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS containing 0.09 % (W/V) Sodium Azide as preservative
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

References for anti-NMDAR2A antibody (ABIN953719)

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Application Details Handling Images back to top
Background publications

Endele, Rosenberger, Geider, Popp, Tamer, Stefanova, Milh, Kortüm, Fritsch, Pientka, Hellenbroich, Kalscheuer, Kohlhase, Moog, Rappold, Rauch, Ropers, von Spiczak, Tönnies, Villeneuve, Villard, Zabel, Zenker, Laube, Reis, Wieczorek, Van Maldergem, Kutsche: "Mutations in GRIN2A and GRIN2B encoding regulatory subunits of NMDA receptors cause variable neurodevelopmental phenotypes." in: Nature genetics, Vol. 42, Issue 11, pp. 1021-6, 2010

King, Eugenin, Hazleton, Morgello, Berman: "Mechanisms of HIV-tat-induced phosphorylation of N-methyl-D-aspartate receptor subunit 2A in human primary neurons: implications for neuroAIDS pathogenesis." in: The American journal of pathology, Vol. 176, Issue 6, pp. 2819-30, 2010

Shimada, Miyagawa, Kawashima, Tanaka, Honda, Honda, Tokunaga: "An approach based on a genome-wide association study reveals candidate loci for narcolepsy." in: Human genetics, Vol. 128, Issue 4, pp. 433-41, 2010

Saus, Brunet, Armengol, Alonso, Crespo, Fernández-Aranda, Guitart, Martín-Santos, Menchón, Navinés, Soria, Torrens, Urretavizcaya, Vallès, Gratacòs, Estivill: "Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients." in: Journal of psychiatric research, Vol. 44, Issue 14, pp. 971-8, 2010

Pinheiro, Bulik, Thornton, Sullivan, Root, Bloss, Berrettini, Schork, Kaye, Bergen, Magistretti, Brandt, Crawford, Crow, Fichter, Goldman, Halmi, Johnson, Kaplan, Keel, Klump, La Via, Mitchell, Strober, Rotondo, Treasure, Woodside: "Association study of 182 candidate genes in anorexia nervosa." in: American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, Vol. 153B, Issue 5, pp. 1070-80, 2010

Images

Product Details anti-NMDAR2A Antibody Target Details NMDAR2A Application Details Handling References for anti-NMDAR2A antibody (ABIN953719) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 1298-1326), (C-Term) antibody (ABIN953719) Flow cytometric analysis of MDA-MB435 cells using NMDA Receptor 2A Antibody (C-term) ...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 1298-1326), (C-Term) antibody (ABIN953719) Immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas ...
Western Blotting (WB) image for anti-Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2a (GRIN2A) (AA 1298-1326), (C-Term) antibody (ABIN953719) Western blot analysis of NMDA Receptor 2A Antibody (C-term) in MDA-MB435 cell line ly...