anti-Rhesus Monkey CD4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended CD4 Antibody (supplied by: Log in to see )

Antigen
CD4 Molecule (CD4) Antibodies
  • cd4
  • L3T4
  • Ly-4
  • CD4mut
  • W3/25
  • p55
  • CD4 molecule
  • carcinoembryonic antigen-related cell adhesion molecule 5
  • T-cell surface glycoprotein CD4
  • CD4 antigen
  • Cd4 molecule
  • CD4
  • LOC100125525
  • cd4
  • Cd4
Reactivity
Cynomolgus, Human, Rhesus Monkey
1271
584
237
71
61
41
36
30
28
26
25
25
22
21
18
18
15
15
13
11
10
9
8
7
5
5
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Host
Rabbit
1348
525
302
13
4
2
1
1
Antibody Type
Recombinant Antibody
Clonality
Chimeric
Conjugate
This CD4 antibody is un-conjugated
253
223
158
133
44
41
39
32
32
32
29
25
24
21
16
16
16
15
15
15
15
15
15
13
10
10
9
8
8
8
8
7
7
6
5
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
1658
545
461
299
287
274
216
164
94
73
54
39
31
26
21
19
18
14
14
11
11
9
6
6
5
4
4
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
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Catalog No. ABIN5668250
$ 345.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5668249 FACS IF IHC (p) IP WB Mouse IgG1, kappa Log in to see MT310 0

General

Antigen CD4 Molecule (CD4) Antibodies
Reactivity Cynomolgus, Human, Rhesus Monkey
(1271), (584), (237), (71), (61), (41), (36), (30), (28), (26), (25), (25), (22), (21), (18), (18), (15), (15), (13), (11), (10), (9), (8), (7), (5), (5), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Host Rabbit
(1348), (525), (302), (13), (4), (2), (1), (1)
Clonality (Clone)
Chimeric   ( )
Conjugate This CD4 antibody is un-conjugated
(253), (223), (158), (133), (44), (41), (39), (32), (32), (32), (29), (25), (24), (21), (16), (16), (16), (15), (15), (15), (15), (15), (15), (13), (10), (10), (9), (8), (8), (8), (8), (7), (7), (6), (5), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(1658), (545), (461), (299), (287), (274), (216), (164), (94), (73), (54), (39), (31), (26), (21), (19), (18), (14), (14), (11), (11), (9), (6), (6), (5), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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Product Details anti-CD4 Antibody

Target Details CD4 Application Details Handling Images
Specificity Mt310 binds to the extracellular domain D1 of CD4 - the same site as the HIV-1 gp120-binding site
Characteristics Rabbit IgG based on the original Mouse IgG1
Purification Purified antibody.
Clone MT310
Isotype IgG, kappa
Plasmids, Primers & others

Target Details CD4

Product Details anti-CD4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name CD4 (CD4 Antibody Abstract)
Background T-cell differentiation antigen, Ly-4, L3T4, T-cell surface antigen T4/Leu-3
Pathways TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events

Application Details

Product Details anti-CD4 Antibody Target Details CD4 Handling Images back to top
Application Notes mt310 can inhibit gp120 binding to CD4, which blocks HIV infectivity of CD4+ T lymphocytes, as well as the binding of MHCII, which results in the block of T-cell activation, possibly leading to the induction of anergy. Antibody binding to CD4 additionally causes the induction of GM-CSF, TNF-a (only after 20?h) and IL-10.
Comment

This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.

Restrictions For Research Use only

Handling

Product Details anti-CD4 Antibody Target Details CD4 Application Details Images back to top
Buffer PBS with 0.02 % Proclin 300.
Preservative ProClin
Precaution of Use This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Images

Product Details anti-CD4 Antibody Target Details CD4 Application Details Handling back to top
Supplier Images
Flow Cytometry (FACS) image for anti-CD4 Molecule (CD4) antibody (ABIN5668250) Flow-cytometry using anti-CD4 antibody MT310 Human lymphocytes were stained with an...
Flow Cytometry (FACS) image for anti-CD4 Molecule (CD4) antibody (ABIN5668250) Flow-cytometry using anti-CD4 antibody MT310 Rhesus monkey lymphocytes were stained...
Flow Cytometry (FACS) image for anti-CD4 Molecule (CD4) antibody (ABIN5668250) Flow-cytometry using anti-CD4 antibody MT310 Cynomolgus monkey lymphocytes were sta...