anti-Rat (Rattus) LAT antibody for Immunofluorescence

Recommended LAT Antibody (supplied by: Log in to see )

Antigen
Linker For Activation of T Cells (LAT) Antibodies
  • LAT
  • lat
  • LAT1
  • pp36
  • linker for activation of T-cells
  • linker for activation of T cells
  • LAT
  • lat
  • Lat
Epitope
pTyr255
31
25
22
22
15
7
5
5
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
284
124
104
3
2
1
Host
Rabbit
172
103
14
2
Clonality
Polyclonal
Conjugate
This LAT antibody is un-conjugated
9
9
8
7
7
6
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
219
81
52
50
39
34
32
8
6
2
2
2
1
1
1
1
1
1
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Available images

Catalog No. ABIN6272038
$ 450.00
Plus shipping costs $45.00

General

Antigen Linker For Activation of T Cells (LAT) Antibodies
Epitope pTyr255
(31), (25), (22), (22), (15), (7), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine), Rat (Rattus)
(284), (124), (104), (3), (2), (1)
Host Rabbit
(172), (103), (14), (2)
Clonality
Polyclonal
Conjugate This LAT antibody is un-conjugated
(9), (9), (8), (7), (7), (6), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1)
Application ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
(219), (81), (52), (50), (39), (34), (32), (8), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1)
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Product Details anti-LAT Antibody

Target Details LAT Application Details Handling Images
Specificity LAT (Phospho-Tyr255) Antibody detects endogenous levels of LAT only when phosphorylated at Tyr255
Cross-Reactivity Human, Mouse (Murine), Rat (Rattus)
Purification The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Immunogen A synthesized peptide derived from human LAT (Phospho-Tyr255)
Isotype IgG
Plasmids, Primers & others

Target Details LAT

Product Details anti-LAT Antibody Application Details Handling Images back to top
Antigen
Alternative Name LAT (LAT Antibody Abstract)
Background

Description: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.

Gene: LAT

Molecular Weight 28kDa
Gene ID 27040
UniProt O43561
Pathways TCR Signaling, Fc-epsilon Receptor Signaling Pathway

Application Details

Product Details anti-LAT Antibody Target Details LAT Handling Images back to top
Application Notes WB 1:1000-3000, IF/ICC 1:100-1:500
Restrictions For Research Use only

Handling

Product Details anti-LAT Antibody Target Details LAT Application Details Images back to top
Format Liquid
Concentration 1 mg/mL
Buffer Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20 °C.Stable for 12 months from date of receipt
Expiry Date 12 months

Images

Product Details anti-LAT Antibody Target Details LAT Application Details Handling back to top
Supplier Images
Immunofluorescence (fixed cells) (IF/ICC) image for anti-Linker For Activation of T Cells (LAT) (pTyr255) antibody (ABIN6272038) ABIN6272039 staining NIH-3T3 by IF/ICC. The sample were fixed with PFA and permeabili...
Western Blotting (WB) image for anti-Linker For Activation of T Cells (LAT) (pTyr255) antibody (ABIN6272038) Western blot analysis of extracts from HepG2, using LAT (Phospho-Tyr255) Antibody.
Western Blotting (WB) image for anti-Linker For Activation of T Cells (LAT) (pTyr255) antibody (ABIN6272038) Western blot analysis of LAT (Phospho-Tyr255) using H2O2 treated 293 whole cell lysates