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|Antigen||Transforming Growth Factor, beta 1 (TGFB1) Antibodies|
|Epitope||AA 340-390 Alternatives|
|Reactivity||Human, Mouse (Murine), Rat (Rattus) Alternatives|
|Conjugate||This TGFB1 antibody is un-conjugated Alternatives|
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
|15 references available|
|Supplier||Log in to see|
Product Details anti-TGFB1 AntibodyTarget Details TGFB1 Application Details Handling References for anti-TGFB1 antibody (ABIN724685) Images
|Purification||Purified by Protein A.|
|Immunogen||KLH conjugated synthetic peptide derived from human TGF-Beta 1|
Target Details TGFB1Product Details anti-TGFB1 Antibody Application Details Handling References for anti-TGFB1 antibody (ABIN724685) Images back to top
|Alternative Name||TGF beta 1 (TGFB1 Antibody Abstract)|
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
Subcellular location: Secreted
Synonyms: CED, LAP, DPD1, TGFB, TGFbeta, Transforming growth factor beta-1, TGF-beta-1, TGFB1
|Research Area||Cancer, Angiogenesis, Growth Factors, Organogenesis|
|Pathways||EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy|
Application DetailsProduct Details anti-TGFB1 Antibody Target Details TGFB1 Handling References for anti-TGFB1 antibody (ABIN724685) Images back to top
|Restrictions||For Research Use only|
HandlingProduct Details anti-TGFB1 Antibody Target Details TGFB1 Application Details References for anti-TGFB1 antibody (ABIN724685) Images back to top
|Buffer||Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.|
|Precaution of Use||This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.|
|Storage Comment||Store at -20°C|
|Expiry Date||12 months|
References for anti-TGFB1 antibody (ABIN724685)Product Details anti-TGFB1 Antibody Target Details TGFB1 Application Details Handling Images back to top
|Product cited in:||
Mao, Zhang, Qi, Jiang, Wu, Lu, Ainiwaer, Shang, Xu, Hao, Shou, Li, Li, Zhang, Bao, Wen: "Efficacy of radiotherapy for the treatment of cystic echinococcosis in naturally infected sheep." in: Infectious diseases of poverty, Vol. 6, Issue 1, pp. 88, 2017 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Sheep (Ovine)).
Shen, Wu, Wang, Zhao, Zhang, Li, Zhao: "Chloroquine attenuates paraquat-induced lung injury in mice by altering inflammation, oxidative stress and fibrosis." in: International immunopharmacology, Vol. 46, pp. 16-22, 2017 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Mouse (Murine)).
Eren, Turgut, Akin, Demir: "The Suppression of Wound Healing Response with Sirolimus and Sunitinib Following Experimental Trabeculectomy in a Rabbit Model." in: Current eye research, Vol. 41, Issue 3, pp. 367-76, 2016
Xue, Chen, Zhao, Zhao, Duan, Zheng: "The Overexpression of TGF-β and CCN2 in Intrauterine Adhesions Involves the NF-κB Signaling Pathway." in: PLoS ONE, Vol. 10, Issue 12, pp. e0146159, 2016
Venter, Marques, Santos, Monte-Alto-Costa: "Use of platelet-rich plasma in deep second- and third-degree burns." in: Burns : journal of the International Society for Burn Injuries, Vol. 42, Issue 4, pp. 807-14, 2016
Ganguly, Wen, Myer, Czech, Sahu, Steinmetz, Raman: "Anti-atherogenic effect of trivalent chromium-loaded CPMV nanoparticles in human aortic smooth muscle cells under hyperglycemic conditions in vitro." in: Nanoscale, Vol. 8, Issue 12, pp. 6542-54, 2016
Zhu, Hu, Yu, Ren, Hu: "High Molecular Weight Hyaluronic Acid Inhibits Fibrosis of Endometrium." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 22, pp. 3438-3445, 2016
Du, Niu, Wang, Zhao, Kong, Zhang, Nan: "TLR4‑dependent signaling pathway modulation: A novel mechanism by which pioglitazone protects against nutritional fibrotic steatohepatitis in mice." in: Molecular medicine reports, Vol. 13, Issue 3, pp. 2159-66, 2016 Method employed by authors: Western Blotting (WB) (Sample species: Mouse (Murine)).
Shang, Liu, Liu, Zhang, Mu, Zhu, Liang, Zhai, Ding, Li, Wen: "Acetyl-11-Keto-β-Boswellic Acid Attenuates Prooxidant and Profibrotic Mechanisms Involving Transforming Growth Factor-β1, and Improves Vascular Remodeling in Spontaneously Hypertensive Rats." in: Scientific reports, Vol. 6, pp. 39809, 2016 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Rat (Rattus)).
Tang, Jiang, Zhou, Xia, Dai: "Increased adenosine levels contribute to ischemic kidney fibrosis in the unilateral ureteral obstruction model." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 737-743, 2015
Hu, Zeng, Jiang, Hu, Meng, Zhu, Mao: "The expression of marker for endometrial stem cell and fibrosis was increased in intrauterine adhesious." in: International journal of clinical and experimental pathology, Vol. 8, Issue 2, pp. 1525-34, 2015
Sun, Li, Wen, Wang, Ji, Ma: "Immunological effect induced by mesenchymal stem cells in a rat liver transplantation model." in: Experimental and therapeutic medicine, Vol. 10, Issue 2, pp. 401-406, 2015
Abdelmagid, Belcher, Moussa, Lababidi, Sondag, Novak, Sanyurah, Frara, Razmpour, Del Carpio-Cano, Safadi: "Mutation in osteoactivin decreases bone formation in vivo and osteoblast differentiation in vitro." in: The American journal of pathology, Vol. 184, Issue 3, pp. 697-713, 2014
Erbas, Yapislar, Oltulu, Yavaso?lu, Aktug, Taskiran: "Nephro-protective effect of granulocyte colony-stimulating factor in streptozotocin induced diabetic rats." in: Biotechnic & histochemistry : official publication of the Biological Stain Commission, Vol. 89, Issue 7, pp. 488-96, 2014
Kou, Hu, Yao, Wang, Shen, Kang, Hong: "Transforming growth factor-?1 promotes Treg commitment in nasal polyposis after intranasal steroid treatment." in: Inflammation research : official journal of the European Histamine Research Society ... [et al.], Vol. 62, Issue 3, pp. 283-9, 2013 Method employed by authors: ELISA (ELISA)
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