anti-Mouse (Murine) IRF5 antibody for Enzyme Immunoassay

Recommended IRF5 Antibody (supplied by: Log in to see )

Antigen
Interferon Regulatory Factor 5 (IRF5) Antibodies
  • IRF5
  • irf5
  • SLEB10
  • AW491843
  • mirf5
  • im:7155364
  • zgc:76986
  • interferon regulatory factor 5
  • interferon regulatory factor 5 L homeolog
  • IRF5
  • irf5
  • Irf5
  • irf5.L
Epitope
AA 176-240
27
18
11
9
6
5
5
4
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine)
139
81
35
10
7
7
6
5
4
3
3
Host
Mouse
74
55
19
9
4
Clonality
Monoclonal
Conjugate
This IRF5 antibody is un-conjugated
4
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
134
75
53
41
33
28
22
9
7
6
3
2
2
1
Supplier
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Catalog No. ABIN121152
$ 412.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5552797 ChIP EIA IHC (p) IP WB Goat C-Term Log in to see Polyclonal 0
1 ABIN320364 EIA IHC (p) IP WB Mouse IgG1 AA 176-240 Log in to see 10T1 0

General

Antigen Interferon Regulatory Factor 5 (IRF5) Antibodies
Epitope AA 176-240
(27), (18), (11), (9), (6), (5), (5), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Human, Mouse (Murine)
(139), (81), (35), (10), (7), (7), (6), (5), (4), (3), (3)
Host Mouse
(74), (55), (19), (9), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This IRF5 antibody is un-conjugated
(4), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(134), (75), (53), (41), (33), (28), (22), (9), (7), (6), (3), (2), (2), (1)
Pubmed 3 references available
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Product Details anti-IRF5 Antibody

Target Details IRF5 Application Details Handling References for anti-IRF5 antibody (ABIN121152) Images
Specificity The antibody recognizes Human and Mouse Interferon Regulatory Factor 5 (IRF-5). Other species not tested.
Purification Protein-G affinity chromatography
Immunogen Recombinant human IRF-5 (176-240 aa) purified from E. coli
Clone 10T1
Isotype IgG1
Plasmids, Primers & others

Target Details IRF5

Product Details anti-IRF5 Antibody Application Details Handling References for anti-IRF5 antibody (ABIN121152) Images back to top
Antigen
Alternative Name IRF5 (IRF5 Antibody Abstract)
Background IRF-5 is a member of IRF family, which plays a critical role in the regulation of genes induced by viral infection, immunostimulation and cell growth regulation. The expression of IRF-5 is limited to lymphoid organs, dendritic cells, and peripheral blood lymphocytes, but is not expressed in numerous leukemia and lymphoma cell lines. Three IRFs(IRF-3, IRF-5, IRF-7) function as direct transducers of virus-mediated signaling and play a critical role in the expression of type I interferon genes and some chemokines.Synonyms: IRF-5, Interferon regulatory factor 5
Gene ID 3663
UniProt Q13568
Pathways TLR Signaling, Autophagy

Application Details

Product Details anti-IRF5 Antibody Target Details IRF5 Handling References for anti-IRF5 antibody (ABIN121152) Images back to top
Application Notes ELISA. Western blot (1/500 - 1/1,000). Immunoprecipitation. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-IRF5 Antibody Target Details IRF5 Application Details References for anti-IRF5 antibody (ABIN121152) Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, pH 7.4, 0.09 % Sodium Azide
Preservative Thimerosal (Merthiolate)
Precaution of Use This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf Life: one year from despatch.
Expiry Date 12 months

References for anti-IRF5 antibody (ABIN121152)

Product Details anti-IRF5 Antibody Target Details IRF5 Application Details Handling Images back to top
Background publications

Ning, Huye, Pagano: "Interferon regulatory factor 5 represses expression of the Epstein-Barr virus oncoprotein LMP1: braking of the IRF7/LMP1 regulatory circuit." in: Journal of virology, Vol. 79, Issue 18, pp. 11671-6, 2005

Barnes, Kellum, Pinder, Frisancho, Pitha: "Interferon regulatory factor 5, a novel mediator of cell cycle arrest and cell death." in: Cancer research, Vol. 63, Issue 19, pp. 6424-31, 2003

Barnes, Moore, Pitha: "Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes." in: The Journal of biological chemistry, Vol. 276, Issue 26, pp. 23382-90, 2001

Images

Product Details anti-IRF5 Antibody Target Details IRF5 Application Details Handling References for anti-IRF5 antibody (ABIN121152) back to top
Supplier Images
Western Blotting (WB) image for anti-Interferon Regulatory Factor 5 (IRF5) (AA 176-240) antibody (ABIN121152) Western blot analysis The extracts of Ramos, THP-1, A20 and NIH3T3 were resolved by S...