anti-Rat (Rattus) DKK1 antibody for Immunofluorescence (Paraffin-embedded Sections)
Recommended DKK1 Antibody (supplied by: Log in to see )
- Antigen
-
Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) Antibodies
show synonyms for this antigen- DKK-1
- SK
- dkk1
- dkk
- dkk-1
- xdkk1
- Xdkk-1
- Dickkopf1
- dickkopf-1
- mdkk-1
- dkk1-A
- dickkopf WNT signaling pathway inhibitor 1
- dickkopf-related protein 1
- dickkopf WNT signaling pathway inhibitor 1b
- dickkopf protein
- dickkopf WNT signaling pathway inhibitor 1 S homeolog
- DKK1
- Dkk1
- LOC100228789
- dkk1b
- dkk1
- dickkopf
- dkk1.S
- Epitope
-
AA 207-247
Alternatives - Reactivity
-
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
Alternatives - Host
-
Rabbit
Alternatives - Clonality
- Conjugate
-
This DKK1 antibody is un-conjugated
Alternatives - Application
-
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives - Options
- Supplier
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- Supplier Product No.
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| Relevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ABIN894060 | IF (p) | Alexa Fluor 488 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN894062 | IF (p) | Alexa Fluor 647 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN894061 | IF (p) | Alexa Fluor 555 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN894064 | IF (p) | Alexa Fluor 350 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN678161 | IF (p) | Cy3 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN678164 | IF (p) | Cy7 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN678162 | IF (p) | Cy5 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN678163 | IF (p) | Cy5.5 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN678165 | IF (p) | FITC | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN2812401 | IF (p) | Alexa Fluor 594 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN5001289 | IF (p) | Alexa Fluor 750 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
| 1 | ABIN5001288 | IF (p) | Alexa Fluor 680 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 |
General |
|
|---|---|
| Antigen | Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) Antibodies |
| Epitope | AA 207-247 Alternatives |
| Reactivity | Dog (Canine), Human, Mouse (Murine), Rat (Rattus) Alternatives |
| Host | Rabbit Alternatives |
| Clonality | |
| Conjugate | This DKK1 antibody is un-conjugated Alternatives |
| Application |
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives
|
|
3 references available |
| Supplier | Log in to see |
Product Details anti-DKK1 AntibodyTarget Details DKK1 Application Details Handling References for anti-DKK1 antibody (ABIN678158) Images |
|
| Purification | Purified by Protein A. |
| Immunogen | KLH conjugated synthetic peptide derived from human DKK1 |
| Isotype | IgG |
| Plasmids, Primers & others | |
Target Details DKK1Product Details anti-DKK1 Antibody Application Details Handling References for anti-DKK1 antibody (ABIN678158) Images back to top |
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| Antigen | |
| Alternative Name | Dkk1 (DKK1 Antibody Abstract) |
| Background |
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Subcellular location: Secreted Synonyms: SK, DKK-1, Dickkopf-related protein 1, Dickkopf-1, hDkk-1, DKK1, UNQ492/PRO18 |
| Gene ID | 22943 |
| UniProt | O94907 |
| Pathways | WNT Signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation |
Application DetailsProduct Details anti-DKK1 Antibody Target Details DKK1 Handling References for anti-DKK1 antibody (ABIN678158) Images back to top |
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| Application Notes |
WB 1:100-1000 IHC-P 1:100-500 IF(IHC-P) 1:50-200 |
| Restrictions | For Research Use only |
HandlingProduct Details anti-DKK1 Antibody Target Details DKK1 Application Details References for anti-DKK1 antibody (ABIN678158) Images back to top |
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| Format | Liquid |
| Concentration | 1 μg/μL |
| Buffer | Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide. |
| Preservative | Sodium azide |
| Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only. |
| Storage | -20 °C |
| Storage Comment | Store at -20°C |
| Expiry Date | 12 months |
References for anti-DKK1 antibody (ABIN678158)Product Details anti-DKK1 Antibody Target Details DKK1 Application Details Handling Images back to top |
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| Product cited in: |
Duan, Yan, Chen, Wu, Han, Guo, Qiao: "TET1 inhibits EMT of ovarian cancer cells through activating Wnt/β-catenin signaling inhibitors DKK1 and SFRP2." in: Gynecologic oncology, Vol. 147, Issue 2, pp. 408-417, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Human). Lu, Duan, Zhang, Wu, Wang: "Expression of Wnt3a, Wnt10b, ?-catenin and DKK1 in periodontium during orthodontic tooth movement in rats." in: Acta odontologica Scandinavica, pp. 1-7, 2015 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Rat (Rattus)). Król, Mucha, Majchrzak, Homa, Bulkowska, Majewska, Gajewska, Pietrzak, Perszko, Romanowska, Paw?owski, Manuali, Hellmen, Motyl: "Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors." in: PLoS ONE, Vol. 9, Issue 1, pp. e83995, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Dog (Canine)). |
ImagesProduct Details anti-DKK1 Antibody Target Details DKK1 Application Details Handling References for anti-DKK1 antibody (ABIN678158) back to top |
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| Supplier Images |
Image kindly provided by Dr. Magdalena Krol. Control tumor cells, tumor cells grown i...
Image kindly submitted by Dr. Magdalena Krol. Formalin-fixed and paraffin embedded ca...
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