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Submit your validation data for this product and get a full refund. I want to validate this productRelevance Score | ABIN | Application | Conjugate | Host | Isotype | Epitope | Supplier | Clonality | References | Details |
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1 | ABIN894062 | IF (p) | Alexa Fluor 647 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
1 | ABIN894061 | IF (p) | Alexa Fluor 555 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
1 | ABIN894060 | IF (p) | Alexa Fluor 488 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
1 | ABIN894064 | IF (p) | Alexa Fluor 350 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
1 | ABIN678162 | IF (p) | Cy5 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
1 | ABIN678164 | IF (p) | Cy7 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
1 | ABIN678165 | IF (p) | FITC | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
1 | ABIN678163 | IF (p) | Cy5.5 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
1 | ABIN678161 | IF (p) | Cy3 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
1 | ABIN2812401 | IF (p) | Alexa Fluor 594 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
1 | ABIN5001289 | IF (p) | Alexa Fluor 750 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 | |
1 | ABIN5001288 | IF (p) | Alexa Fluor 680 | Rabbit | IgG | AA 207-247 | Log in to see | Polyclonal | 0 |
General |
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Antigen | Dickkopf Homolog 1 (Xenopus Laevis) (DKK1) Antibodies |
Epitope | AA 207-247 Alternatives |
Reactivity | Dog (Canine), Human, Mouse (Murine), Rat (Rattus) Alternatives |
Host | Rabbit Alternatives |
Clonality | |
Conjugate | This DKK1 antibody is un-conjugated Alternatives |
Application |
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
Alternatives
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3 references available |
Supplier | Log in to see |
Product Details anti-DKK1 AntibodyTarget Details DKK1 Application Details Handling References for anti-DKK1 antibody (ABIN678158) Images |
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Purification | Purified by Protein A. |
Immunogen | KLH conjugated synthetic peptide derived from human DKK1 |
Isotype | IgG |
Plasmids, Primers & others | |
Target Details DKK1Product Details anti-DKK1 Antibody Application Details Handling References for anti-DKK1 antibody (ABIN678158) Images back to top |
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Antigen | |
Alternative Name | Dkk1 (DKK1 Antibody Abstract) |
Background |
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Subcellular location: Secreted Synonyms: SK, DKK-1, Dickkopf-related protein 1, Dickkopf-1, hDkk-1, DKK1, UNQ492/PRO18 |
Gene ID | 22943 |
UniProt | O94907 |
Pathways | WNT Signaling, Regulation of Muscle Cell Differentiation, Positive Regulation of fat Cell Differentiation |
Application DetailsProduct Details anti-DKK1 Antibody Target Details DKK1 Handling References for anti-DKK1 antibody (ABIN678158) Images back to top |
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Application Notes |
WB 1:100-1000 IHC-P 1:100-500 IF(IHC-P) 1:50-200 |
Restrictions | For Research Use only |
HandlingProduct Details anti-DKK1 Antibody Target Details DKK1 Application Details References for anti-DKK1 antibody (ABIN678158) Images back to top |
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Format | Liquid |
Concentration | 1 μg/μL |
Buffer | Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide. |
Preservative | Sodium azide |
Precaution of Use | This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only. |
Storage | -20 °C |
Storage Comment | Store at -20°C |
Expiry Date | 12 months |
References for anti-DKK1 antibody (ABIN678158)Product Details anti-DKK1 Antibody Target Details DKK1 Application Details Handling Images back to top |
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Product cited in: |
Duan, Yan, Chen, Wu, Han, Guo, Qiao: "TET1 inhibits EMT of ovarian cancer cells through activating Wnt/β-catenin signaling inhibitors DKK1 and SFRP2." in: Gynecologic oncology, Vol. 147, Issue 2, pp. 408-417, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Human). Lu, Duan, Zhang, Wu, Wang: "Expression of Wnt3a, Wnt10b, ?-catenin and DKK1 in periodontium during orthodontic tooth movement in rats." in: Acta odontologica Scandinavica, pp. 1-7, 2015 Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Rat (Rattus)). Król, Mucha, Majchrzak, Homa, Bulkowska, Majewska, Gajewska, Pietrzak, Perszko, Romanowska, Paw?owski, Manuali, Hellmen, Motyl: "Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors." in: PLoS ONE, Vol. 9, Issue 1, pp. e83995, 2014 Method employed by authors: Western Blotting (WB) (Sample species: Dog (Canine)). |
ImagesProduct Details anti-DKK1 Antibody Target Details DKK1 Application Details Handling References for anti-DKK1 antibody (ABIN678158) back to top |
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Supplier Images |