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anti-Fibulin 5 (FBLN5) Antibodies

The protein encoded by FBLN5 is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. Additionally we are shipping Fibulin 5 Kits (37) and Fibulin 5 Proteins (15) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
FBLN5 10516 Q9UBX5
FBLN5 23876 Q9WVH9
FBLN5 29158 Q9WVH8
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Top anti-Fibulin 5 Antibodies at antibodies-online.com

Showing 10 out of 129 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN185699 (0.1µg/ml) staining of Human Ovary lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated ELISA, WB Figure 1: Western blot analysis using fibulin5 mouse mAb against truncated fibulin5 recombinant protein (1) and Hela cell lysate (2) . 100 μL Log in to see 3 to 4 Days
$272.80
Details
Human Mouse Un-conjugated IHC, ELISA, WB Figure 1: Immunohistochemical analysis of paraffin-embedded human colon cancer (left) and breast cancer (right) showing cytoplasmic localization with DAB staining using FBLN5 mouse mAb. Figure 2: Western blot analysis using FBLN5 mouse mAb against truncated FBLN5-His recombinant protein. 100 μL Log in to see 3 to 4 Days
$442.20
Details
Human Mouse Un-conjugated IHC, ELISA, WB Figure 1: Immunohistochemical analysis of paraffin-embedded human stomach carcinoma (left) and breast carcinoma (right), showing cytoplasmic localization using fibulin5 mouse mAb with DAB staining. Figure 2: Western blot analysis using Fibulin5 mouse mAb against truncated fibulin5 recombinant protein (1) and Hela cell lysate (2) . 100 μL Log in to see 3 to 4 Days
$442.20
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 0.1 mL Log in to see 6 to 8 Days
$286.00
Details
Human Mouse Un-conjugated IHC, WB   100 μL Log in to see 10 to 11 Days
$464.29
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using FBLN5 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human placenta tissue with Anti-Fibulin 5 Polyclonal Antibody (ABIN728473), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining L1 rat brain, L2 human colon carcinoma lysates probed (ABIN728473) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted and observed band size: 50kDa. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB FBLN5 Antibody (C-term)  western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the FBLN5 antibody detected the FBLN5 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details

FBLN5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-Fibulin 5 Antibodies

  1. Human Monoclonal Fibulin 5 Primary Antibody for IHC, ELISA - ABIN969131 : Markova, Zou, Ringpfeil, Sasaki, Kostka, Timpl, Uitto, Chu: Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene. in American journal of human genetics 2003 (PubMed)
    Show all 4 references for ABIN969131

  2. Human Monoclonal Fibulin 5 Primary Antibody for ELISA, WB - ABIN969145 : Wen, Hochholdinger, Sauer, Bruce, Schnable: The roothairless1 gene of maize encodes a homolog of sec3, which is involved in polar exocytosis. in Plant physiology 2005 (PubMed)
    Show all 4 references for ABIN969145

  3. Human Monoclonal Fibulin 5 Primary Antibody for IHC, ELISA - ABIN969144 : Kadoya, Sasaki, Kostka, Timpl, Matsuzaki, Kumagai, Sakai, Nishiyama, Amano: Fibulin-5 deposition in human skin: decrease with ageing and ultraviolet B exposure and increase in solar elastosis. in The British journal of dermatology 2005 (PubMed)
    Show all 4 references for ABIN969144

  4. Human Monoclonal Fibulin 5 Primary Antibody for EIA, IHC (p) - ABIN1107240 : Lee, Roy, Mogford, Schiemann, Mustoe: Fibulin-5 promotes wound healing in vivo. in Journal of the American College of Surgeons 2004 (PubMed)
    Show all 3 references for ABIN1107240

  5. Human Monoclonal Fibulin 5 Primary Antibody for IHC, WB - ABIN2869298 : Clark, Gurney, Abaya, Baker, Baldwin, Brush, Chen, Chow, Chui, Crowley, Currell, Deuel, Dowd, Eaton, Foster, Grimaldi, Gu, Hass, Heldens, Huang, Kim, Klimowski, Jin, Johnson, Lee, Lewis, Liao, Mark et al.: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ... in Genome research 2003 (PubMed)
    Show all 2 references for ABIN2869298

  6. Human Polyclonal Fibulin 5 Primary Antibody for ELISA, WB - ABIN185699 : Albig, Neil, Schiemann: Fibulins 3 and 5 antagonize tumor angiogenesis in vivo. in Cancer research 2006 (PubMed)

More Antibodies against Fibulin 5 Interaction Partners

Human Fibulin 5 (FBLN5) interaction partners

  1. study demonstrates the pivotal role of the extracellular protein, fibulin-5, on the adhesion and proliferation of human keloid-derived cells, through binding to integrin beta-1 (show ITGB1 Antibodies)

  2. Lower FBLN-5 expression is an important indicator of poor survival in hepatocellular carcinoma. FBLN-5 inhibits HCC (show FAM126A Antibodies) adhesion/motility via integrin-dependent mechanism.

  3. FBLN5 mRNA expression is upregulated in response to cAMP-mediated decidualization of primary human endometrial stromal cells, although FBLN5 itself does not enhance decidualization

  4. Fibulin-5 is significantly down-regulated in ovarian carcinoma and acts as a tumour suppressor by inhibiting the migration and invasion of ovarian cancer cells.

  5. Data indicate that Fbln5 promotes PDAC progression by functioning as a molecular rheostat that modulates cell-ECM (show MMRN1 Antibodies) interactions to reduce ROS (show ROS1 Antibodies) production, and thus tip the balance in favor of tumor cell survival and treatment-refractory disease.

  6. Data suggest that fibulin-5 functions as a metastasis suppressor in lung cancer by modulating tumor microenvironment to suppress Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.

  7. Fibulin-5 may be implicated in the aetiology of rectal prolapse in a subgroup of young male patients.

  8. Fibulin-5 expression is a disease marker of hepatic fibrosis.

  9. Loss of FBLN5 expression is associated with glioma.

  10. Up-regulation of elastin (show ELN Antibodies) and fibulin-5 mRNA levels in ICA were strongly correlated with family history of cardiovascular disease when compared to CCA (show FBN2 Antibodies)

Mouse (Murine) Fibulin 5 (FBLN5) interaction partners

  1. Data indicate that Fbln5 promotes PDAC progression by functioning as a molecular rheostat that modulates cell-ECM (show MMRN1 Antibodies) interactions to reduce ROS (show ROS1 Antibodies) production, and thus tip the balance in favor of tumor cell survival and treatment-refractory disease.

  2. While premaxillo-maxillary suture mesenchymal cells in fibulin-5-null mice were capable of differentiating into osteoblasts, suture cells in mutant mice were less proliferative.

  3. Fibulin-5 plays critical roles in proliferation, migration and invasion of certain tumors, and the effect of fibulin-5 on tumorigenesis appears to be largely context-dependent. (Review)

  4. These results are consistent with a role for TGFbeta2 in lung septation and for Ltbp4 (show LTBP4 Antibodies) in regulating fibulin-5 dependent elastic fiber assembly.

  5. Without LTBP-4 (show LTBP4 Antibodies), fibulin-5 and tropoelastin (show ELN Antibodies) deposition was discontinuous and punctate in vitro and in vivo

  6. This study used the maturation of fibulin-5 knockout (KO) and wild-type mice to study the effects of fragmented elastic fibers on the growth and remodeling of carotid arteries.

  7. suggest that uPA (show PLAU Antibodies) promotes cell migration by binding to fibulin-5, initiating its cleavage by plasmin (show PLG Antibodies), which leads to its dissociation from beta1-integrin and thereby unblocks the capacity of integrin to facilitate cell motility

  8. MMP9 (show MMP9 Antibodies) and fibulin-5 have roles in progression of pelvic organ prolapse in mice and humans

  9. mechanical testing and confocal imaging of common carotid arteries from fibulin-5 null mice and littermate controls to characterize the mechanical behavior and microstructural content of these arteries

  10. These findings introduce a novel function for Fbln5 in the regulation of integrin-induced reactive oxygen species production.

Cow (Bovine) Fibulin 5 (FBLN5) interaction partners

  1. These results suggest a novel regulatory mechanism of elastic fiber assembly in which LTBP-2 (show LTBP2 Antibodies) regulates targeting of DANCE on suitable microfibrils to form elastic fibers.

Fibulin 5 (FBLN5) Antigen Profile

Protein Summary

The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

Gene names and symbols associated with anti-Fibulin 5 (FBLN5) Antibodies

  • fibulin 5 (fbln5) antibody
  • fibulin 5 (FBLN5) antibody
  • fibulin 5 (LOC100222931) antibody
  • fibulin 5 (Fbln5) antibody
  • Fibulin 5 (LOC100155248) antibody
  • A55 antibody
  • ADCL2 antibody
  • ARCL1A antibody
  • ARMD3 antibody
  • DANCE antibody
  • DKFZp469K0327 antibody
  • EVEC antibody
  • FBLN5 antibody
  • FIBL-5 antibody
  • Fibulin-5 antibody
  • MGC108414 antibody
  • UP50 antibody
  • zgc:103575 antibody

Protein level used designations for anti-Fibulin 5 (FBLN5) Antibodies

fibulin-5 , fibulin 5 , fibulin-5-like , developmental arteries and neural crest EGF-like protein , urine p50 protein , FIBL-5 , EVEC , dance , embryonic vascular EGF repeat-containing protein

GENE ID SPECIES
449806 Danio rerio
453112 Pan troglodytes
595007 Xenopus (Silurana) tropicalis
697372 Macaca mulatta
100172278 Pongo abelii
100222931 Taeniopygia guttata
100392828 Callithrix jacchus
100480209 Ailuropoda melanoleuca
100588580 Nomascus leucogenys
10516 Homo sapiens
480227 Canis lupus familiaris
23876 Mus musculus
29158 Rattus norvegicus
535185 Bos taurus
100347343 Oryctolagus cuniculus
100715192 Cavia porcellus
100155248 Sus scrofa
423413 Gallus gallus
101112927 Ovis aries
100063331 Equus caballus
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