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anti-Glucokinase (Hexokinase 4) Regulator (GCKR) Antibodies

GCKR encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. Additionally we are shipping GCKR Kits (23) and GCKR Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
GCKR 2646 Q14397
GCKR 25658 Q07071
GCKR 231103 Q91X44
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Top anti-GCKR Antibodies at antibodies-online.com

Showing 10 out of 85 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 5 to 7 Days
$408.19
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from mouse heart/rat heart cells, using Glucokinase Regulator Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Mouse Un-conjugated IF, WB Anti-GCKR mouse monoclonal antibody (ABIN2454032) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY GCKR (RC214230). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GCKR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-GCKR. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Rabbit Un-conjugated WB Host: RabbitTarget Name: GCKRAntibody Dilution: 1.0ug/mlSample Tissue: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, IHC, WB Anti-GCKR mouse monoclonal antibody (ABIN2454023) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY GCKR (RC214230). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GCKR (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-GCKR. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of GCKR expression in A431 (A), mouse heart (B), PC12 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details

GCKR Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-GCKR Antibodies

  1. Mouse (Murine) Polyclonal GCKR Primary Antibody for ELISA, WB - ABIN451749 : Kathiresan, Melander, Guiducci, Surti, Burtt, Rieder, Cooper, Roos, Voight, Havulinna, Wahlstrand, Hedner, Corella, Tai, Ordovas, Berglund, Vartiainen, Jousilahti, Hedblad, Taskinen, Newton-Cheh et al.: Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. ... in Nature genetics 2008 (PubMed)
    Show all 2 references for ABIN451749

  2. Human Polyclonal GCKR Primary Antibody for ELISA, WB - ABIN1533887 : Hayward, Dunlop, Intody, Leek, Markham, Warner, Bonthron: Organization of the human glucokinase regulator gene GCKR. in Genomics 1998 (PubMed)

More Antibodies against GCKR Interaction Partners

Human Glucokinase (Hexokinase 4) Regulator (GCKR) interaction partners

  1. The present study explored the association between a common variant of the glucokinase regulator (GCKR) gene and metabolic syndrome and its related traits in Taiwanese adolescents

  2. This study shows that in patients with type 2 diabetes who were not selected for liver abnormalities, liver fat content was related to GCKR rs1260326 polymorphism

  3. Lifestyle Intervention for Weight Loss and Cardiometabolic Changes in the Setting of Glucokinase Regulatory Protein Inhibition: Glucokinase Regulatory Protein-Leu446Pro Variant in Look AHEAD

  4. The GCKR rs780092 variant showed opposite-directional associations with type 2 diabetes and hypertriacylglycerolaemia in a Chinese population.

  5. Given that acetylated GKRP may affiliate with type-2 diabetes mellitus (T2DM), understanding the mechanism of GKRP acetylation in the liver could reveal novel targets within the GK-GKRP pathway, for treating T2DM and other metabolic pathologies.

  6. The AA genotype of the GCKR rs780094 polymorphism may increase the risk of T2D among ethnic Uygurs from Xinjiang.

  7. Two new polymorphisms associated with gall bladder disease and obesity in women have been identified, GCKR rs1260326, and TTC39B rs686030.

  8. We found that the PPARGC1A (show PPARGC1A Antibodies) and PNPLA3 (show PNPLA3 Antibodies) variants, but not the GCKR variant, were associated with NASH (show SAMSN1 Antibodies).

  9. Disruption of the GKRP-glucokinase (show GCK Antibodies) complex is a promising new antidiabetic target, since it results in lower plasma glucose levels without inducing hypoglycemia[review]

  10. this is the first evidence that n-3 LC-PUFAs may modulate the impact of the GCKR rs1260326 polymorphism on TG concentrations in adolescents. Several molecular mechanisms, in link with glucose uptake, could explain these findings

Xenopus laevis Glucokinase (Hexokinase 4) Regulator (GCKR) interaction partners

  1. Glucokinase regulatory protein binds to a super-open conformation of GK mainly through hydrophobic interaction, inhibiting the GK activity by locking a small domain of GK.

Mouse (Murine) Glucokinase (Hexokinase 4) Regulator (GCKR) interaction partners

  1. Given that acetylated GKRP may affiliate with type-2 diabetes mellitus (T2DM), understanding the mechanism of GKRP acetylation in the liver could reveal novel targets within the GK-GKRP pathway, for treating T2DM and other metabolic pathologies.

  2. Germinal center kinase-related (show MAP4K5 Antibodies) enzyme (GCKR) facilitates both canonical and noncanonical Wnt (show WNT2 Antibodies) signaling in B lymphocytes.

GCKR Antigen Profile

Protein Summary

This gene encodes a protein belonging to the GCKR subfamily of the SIS (Sugar ISomerase) family of proteins. The gene product is a regulatory protein that inhibits glucokinase in liver and pancreatic islet cells by binding non-covalently to form an inactive complex with the enzyme. This gene is considered a susceptibility gene candidate for a form of maturity-onset diabetes of the young (MODY).

Gene names and symbols associated with GCKR

  • glucokinase (hexokinase 4) regulator (GCKR) antibody
  • glucokinase (hexokinase 4) regulator (Gckr) antibody
  • glucokinase regulator (MGC68583) antibody
  • glucokinase regulatory protein (Gckr) antibody
  • glucokinase regulatory protein-like (LOC100350724) antibody
  • mitogen-activated protein kinase kinase kinase kinase 5 (Map4k5) antibody
  • 4432415E19Rik antibody
  • FGQTL5 antibody
  • GCKR antibody
  • GKRP antibody
  • GLRE antibody
  • KHS antibody
  • MAPKKKK5 antibody

Protein level used designations for GCKR

glucokinase regulatory protein , glucokinase regulator , MAPK/ERK kinase kinase kinase 5 , MEK kinase kinase 5 , MEKKK 5

GENE ID SPECIES
100071177 Equus caballus
2646 Homo sapiens
25658 Rattus norvegicus
100728544 Cavia porcellus
100625192 Sus scrofa
475705 Canis lupus familiaris
398839 Xenopus laevis
231103 Mus musculus
100350724 Oryctolagus cuniculus
399510 Mus musculus
Selected quality suppliers for anti-GCKR (GCKR) Antibodies
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