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anti-Runt-Related Transcription Factor 2 (RUNX2) Antibodies

RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. Additionally we are shipping RUNX2 Kits (42) and RUNX2 Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RUNX2 12393 Q08775
RUNX2 860 Q13950
RUNX2 367218  
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Top anti-RUNX2 Antibodies at antibodies-online.com

Showing 10 out of 236 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-RUNX2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:2500Positive Control: HepG2 cell lysate Sample Type: Lane 1:241 µg mouse mesenchymal stem cell lysate Primary Antibody Dilution: 1:0000Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:00,000 Color/Signal Descriptions: RUNX2  Gene Name: Anonymous Submitted by: 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-RUNX2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate WB Suggested Anti-RUNX2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control:.21_B cell lysate  RUNX2 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RUNX2 Antibody Titration: 1.25ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated DB Dot blot analysis of anti-Phospho-RUNX2-S533 Antibody (ABIN389942) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of anti-RUNX2 Antibody (S533) (ABIN392133) in HepG2 cell line lysates (35 µg/lane). RUNX2 (arrow) was detected using the purified polyclonal antibody. RUNX2 Antibody (S533) (ABIN392133) western blot analysis in Hob cell line lysates.This demonstrates the RUNX2 antibody detected the RUNX2 protein (arrow)(Kindly provided by Dr. John Wu). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-RUNX2 Antibody Titration: 1.25ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB Observed bind size: 62KD Anti-RUNX2 Picoband antibody,  All lanes: Anti RUNX2  at 0.5ug/ml WB: Recombinant Human RUNX2 Protein 0.5ng Predicted bind size: 50KD Observed bind size: 50KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC (p), WB Immunohistochemistry with CBFA1 Polyclonal Antibody 0.1 mg Log in to see 6 to 8 Days
$313.50
Details

RUNX2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-RUNX2 Antibodies

  1. Human Polyclonal RUNX2 Primary Antibody for DB - ABIN389942 : McNamara, Sjöström, Burgess, Kim, Liu, Gordonov, Moghe, Meek, Oreffo, Su, Dalby: Skeletal stem cell physiology on functionally distinct titania nanotopographies. in Biomaterials 2011 (PubMed)
    Show all 8 references for ABIN389942

  2. Human Polyclonal RUNX2 Primary Antibody for EIA - ABIN358487 : Ermakov, Malkin, Keter, Kobyliansky, Livshits: Family-based association study of polymorphisms in the RUNX2 locus with hand bone length and hand BMD. in Annals of human genetics 2008 (PubMed)
    Show all 3 references for ABIN358487

  3. Human Polyclonal RUNX2 Primary Antibody for WB - ABIN2780588 : Lee, Lee, Ryoo, Park, Park, Bae, Cho, Park: The odontogenic ameloblast-associated protein (ODAM) cooperates with RUNX2 and modulates enamel mineralization via regulation of MMP-20. in Journal of cellular biochemistry 2010 (PubMed)
    Show all 2 references for ABIN2780588

  4. Human Polyclonal RUNX2 Primary Antibody for EIA, WB - ABIN360019 : Rich, Rosová, Nolta, Myckatyn, Sandell, McAlinden: Upregulation of Runx2 and Osterix during in vitro chondrogenesis of human adipose-derived stromal cells. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 references for ABIN360019

  5. Cow (Bovine) Polyclonal RUNX2 Primary Antibody for WB - ABIN2774905 : Guo, Chung, Yang, Karsenty, Bringhurst, Kronenberg: PTH/PTHrP receptor delays chondrocyte hypertrophy via both Runx2-dependent and -independent pathways. in Developmental biology 2006 (PubMed)
    Show all 2 references for ABIN2774905

  6. Chicken Polyclonal RUNX2 Primary Antibody for WB - ABIN2774906 : Ducy, Zhang, Geoffroy, Ridall, Karsenty: Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. in Cell 1997 (PubMed)

More Antibodies against RUNX2 Interaction Partners

Zebrafish Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Runx2 may have an evolutionarily conserved role in axis formation

Mouse (Murine) Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. in murine bone marrow stromal cells undergoing osteogenic differentiation, TNF-alpha (show TNF Antibodies) and it activated NF-kappaB (show NFKB1 Antibodies) pathway inhibit the expression of Runx2 gene, and suppress the Runx2-mediated osteogenic gene transcription via the 9.0 kb BSP (show KLK6 Antibodies) promoter.

  2. results suggest that 1,25(OH)D induces the transdifferentiation of osteoblasts to adipocytes via Runx2 downregulation in osteoblasts.

  3. In a model of instability-induced osteoarthritis, Runx2 was overexpressed in articular chondrocytes and osteophyte-forming cells in LOX-1 (show OLR1 Antibodies)(+)/(+) mice and was significantly downregulated in articular chondrocytes and osteophyte-forming cells in LOX-1 (show OLR1 Antibodies)(-)/(-) mice.

  4. miR23b inhibits BMP9induced C2C12 myoblast osteogenesis via targeting of the Runx2 gene, acting as a suppressor.

  5. Runx2-modified adipose-derived stem cells promote tendon graft integration in anterior cruciate ligament reconstruction.

  6. FHL2 (show FHL2 Antibodies) might interact with Runx2 to mediate mesenchymal cell differentiation at the early stages of tooth development and human dental pulp cell differentiation.

  7. our studies reveal a novel function for Runx2 in regulating mammary epithelial cell regenerative potential, possibly acting as a downstream target of WNT (show WNT2 Antibodies) signalling.

  8. MED23 (show MED23 Antibodies) binds to RUNX2 and modulates its transcriptional activity.

  9. Hand1 (show HAND1 Antibodies) downregulated Ihh (show IHH Antibodies) gene expression in vitro by inhibiting Runx2 transactivation of the Ihh (show IHH Antibodies) proximal promoter.

  10. increased intranuclear actin forces MSC (show MSC Antibodies) into osteogenic lineage through controlling Runx2 activity; this process may be useful for clinical objectives of forming bone.

Human Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. The results indicate that Runx2 could promote EMT (show ITK Antibodies) and VM formation in HCC (show FAM126A Antibodies) and Galectin-3 (show LGALS3 Antibodies) might have some function in this process.

  2. the findings of the present study provided novel insights into the control of IPO8 (show IPO8 Antibodies) transcription, and may enhance understanding regarding RUNX2 regulatory mechanisms in osteoblast differentiation, bone development, and degenerative bone disease.

  3. Findings suggest thatSirt1 may regulate the expression of Runx2, which is the osteogenic transcription factor, and the production of MMP-13 (show MMP13 Antibodies) from chondrocytes in OA.

  4. Runx2 is a direct downstream target of miR (show MLXIP Antibodies)-455 in hepatocellular carcinoma.

  5. The predictability of Runx2 for OS in stage IV tumours differs with different ER states.

  6. the findings of this study provide evidence of the upregulation of miR628-3p in patients with atrophic non-union and that miR628-3p may exert an inhibitory effect on osteogenesis via the suppression of its target gene, RUNX2.

  7. miR (show MLXIP Antibodies)-205 acts as a tumor suppressor in human osteosarcoma via directly targeting RUNX2.

  8. BMP2 (show BMP2 Antibodies) and RUNX2 are expressed exclusively by osteoblasts whereas DSPP (show DSPP Antibodies) and LOXL2 (show LOXL2 Antibodies) are expressed exclusively by odontoblasts. (Review)

  9. Study identified a sporadic CCD patient carrying a novel insertion/frameshift mutation of RUNX2.

  10. our results reveal that RUNX2 promotes hepatocellular carcinoma (HCC (show FAM126A Antibodies)) cell migration and invasion by MMP9 (show MMP9 Antibodies)-mediated pathway, and potentially serves as a new prognostic biomarker and in therapeutic strategies for HCC (show FAM126A Antibodies).

Rabbit Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Runx2-modified adipose-derived stem cells promote tendon graft integration in anterior cruciate ligament reconstruction.

  2. The OPG (show TNFSF11 Antibodies) expression levels decreased while those of RANKL (show TNFSF11 Antibodies) and RUNX2 increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

Xenopus laevis Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. These data also indicate that MGP (show MGP Antibodies) is under dual regulation by runx2 through the use of various isoforms and context-dependent formation of transcriptional complexes.

RUNX2 Antigen Profile

Protein Summary

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

Gene names and symbols associated with RUNX2

  • runt-related transcription factor 2a (runx2a) antibody
  • transcription factor Cbfa1 (runx2) antibody
  • runt-related transcription factor 2 (RUNX2) antibody
  • runt-related transcription factor 2 (runx2) antibody
  • runt related transcription factor 2 (Runx2) antibody
  • runt-related transcription factor 2 (Runx2) antibody
  • runt-related transcription factor 2 (LOC100339156) antibody
  • runt-related transcription factor 2-like (LOC100737965) antibody
  • AML3 antibody
  • Cbf antibody
  • CBF-alpha-1 antibody
  • Cbfa-1 antibody
  • CBFA1 antibody
  • CCD antibody
  • CCD1 antibody
  • CLCD antibody
  • LS3 antibody
  • OSF-2 antibody
  • OSF2 antibody
  • PEA2aA antibody
  • Pebp2a1 antibody
  • pebp2a2 antibody
  • PEBP2aA antibody
  • pebp2aa1 antibody
  • Pebpa2a antibody
  • RUNX2 antibody

Protein level used designations for RUNX2

runt-related transcription factor 2 , transcription factor Runx2a , transcription factor Cbfa1 , runt-related transcription factor 2-like , AKV core binding factor , CBF-alpha-1 , PEA2-alpha A , PEBP2 alpha A , SL3-3 enhancer factor 1 alpha A subunit , acute myeloid leukemia 3 protein , core binding factor alpha 1 , osteoblast-specific transcription factor 2 , polyomavirus enhancer-binding protein 2 alpha A subunit , runt domain, alpha subunit 1 , PEBP2-alpha A , SL3/AKV core-binding factor alpha A subunit , core-binding factor, runt domain, alpha subunit 1 , oncogene AML-3 , runt-related factor 2 , core-binding factor subunit alpha-1 , runt related transcription factor 2 , Runx2 spliced isoform , runt-related transcription factor 2 type I , runt-related transcription factor 2 type II , core binding factor alpha 1 subunit

GENE ID SPECIES
405784 Danio rerio
445986 Takifugu rubripes
449531 Canis lupus familiaris
472017 Pan troglodytes
703331 Macaca mulatta
100080409 Ornithorhynchus anatinus
100189546 Xenopus (Silurana) tropicalis
100222668 Taeniopygia guttata
100406564 Callithrix jacchus
100453201 Pongo abelii
100549663 Meleagris gallopavo
100555776 Anolis carolinensis
100619969 Monodelphis domestica
12393 Mus musculus
860 Homo sapiens
474923 Canis lupus familiaris
536911 Bos taurus
100008943 Oryctolagus cuniculus
367218 Rattus norvegicus
100037059 Xenopus laevis
373919 Gallus gallus
100734175 Cavia porcellus
100033890 Equus caballus
100155806 Sus scrofa
100339156 Oryctolagus cuniculus
100861217 Capra hircus
101115489 Ovis aries
100737965 Sus scrofa
Selected quality suppliers for anti-RUNX2 (RUNX2) Antibodies
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