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anti-phosphodiesterase 3B, CGMP-Inhibited (PDE3B) Antibodies

catalyzes the hydrolysis of cAMP and cGMP; regulates insulin secretory processes. Additionally we are shipping and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDE3B 5140 Q13370
PDE3B 18576 Q61409
PDE3B 29516 Q63085
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Top anti-PDE3B Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-PDE3B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: 293T cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IF, WB Confocal immunofluorescent analysis of PDE3B Antibody (Center) (ABIN655957) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, FACS, IF, WB Flow cytometric analysis of Jurkat cells using PDE3B Antibody (Center) Cat.-No AP53235PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of PDE3B Antibody (Center) Cat.-No AP53235PU-N with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated EIA, IP, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Goat Un-conjugated EIA, IP, WB   0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged PDE3B is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IHC (fro), IP, WB 0.1 mL Log in to see 6 to 8 Days
$533.50
Details
Human Rabbit Un-conjugated WB 200 μg Log in to see 2 to 3 Days
$283.50
Details

PDE3B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-PDE3B Antibodies

  1. Human Polyclonal PDE3B Primary Antibody for EIA, IP - ABIN493243 : Reinhardt, Chin, Zhou, Taira, Murata, Manganiello, Bondy: Distinctive anatomical patterns of gene expression for cGMP-inhibited cyclic nucleotide phosphodiesterases. in The Journal of clinical investigation 1995 (PubMed)
    Show all 3 references for ABIN493243

  2. Human Polyclonal PDE3B Primary Antibody for EIA, FACS - ABIN954064 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
    Show all 3 references for ABIN954064

  3. Human Polyclonal PDE3B Primary Antibody for EIA, IP - ABIN493242 : Meacci, Taira, Moos, Smith, Movsesian, Degerman, Belfrage, Manganiello: Molecular cloning and expression of human myocardial cGMP-inhibited cAMP phosphodiesterase. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Show all 3 references for ABIN493242

  4. Human Polyclonal PDE3B Primary Antibody for ELISA, WB - ABIN562146 : Bazhin, Kahnert, Kimpfler, Schadendorf, Umansky: Distinct metabolism of cyclic adenosine monophosphate in regulatory and helper CD4+ T cells. in Molecular immunology 2010 (PubMed)

  5. Chicken Polyclonal PDE3B Primary Antibody for WB - ABIN2781829 : Raymond, Wilson, Carter, Maurice: Numerous distinct PKA-, or EPAC-based, signalling complexes allow selective phosphodiesterase 3 and phosphodiesterase 4 coordination of cell adhesion. in Cellular signalling 2007 (PubMed)

More Antibodies against PDE3B Interaction Partners

Human phosphodiesterase 3B, CGMP-Inhibited (PDE3B) interaction partners

  1. Our results shed more light on phosphodiesterase 3A (show PDE3A Antibodies) activation and could be relevant to the treatment of severe hypertension in the general population.

  2. Data indicate that genome-wide significant associations were found both at age 6 and 14 with single nucleotide polymorphisms (SNPs) on chromosome 11p15 in phosphodiesterase 3B, cGMP-inhibited protein PDE3B/cytochrome P-450 (show CYP Antibodies) CYP2R1 (show CYP2R1 Antibodies) genes.

  3. PDE3B appears to be an important actor in regulation of energy metabolism and energy intake. Is inhibition of PDE3B a possible target for treatment of obesity or type 2 diabetes mellitus? [REVIEW]

  4. PDE3B and the anti-lipolytic action of insulin (show INS Antibodies) may have a role in increased S-nitrosylation of adipose tissue in obesity

  5. PDE3B is activated in response to agents relevant for beta-cell function and activation is linked to increased as well as decreased phosphorylation of the enzyme

  6. PDE3B and EPAC1 (show RAPGEF3 Antibodies) bind directly through protein-protein interactions

  7. Data suggest that five novel genes, LUM (show LUM Antibodies), PDE3B, PDGF-C (show PDGFC Antibodies), NRG1 (show NRG1 Antibodies) and PKD2 (show PKD2 Antibodies), have great potential for predicting the efficacy of cisplatin-based chemotherapy against OSCC.

  8. Inhibition of PDE3B augments PDE4 (show PDE4A Antibodies) inhibitor-induced apoptosis in a subset of patients with chronic lymphocytic leukemia

  9. Results explain the dual cyclic AMP (show APRT Antibodies)/cyclic GMP (show NT5C2 Antibodies) binding capabilities of phosphodiesterase 3B and provide the molecular basis for inhibitor specificity.

  10. p87PIKAP (show PIK3R6 Antibodies) is a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B [p87PIKAP (show PIK3R6 Antibodies)]

Mouse (Murine) phosphodiesterase 3B, CGMP-Inhibited (PDE3B) interaction partners

  1. These results suggest the possibility for a direct role for the PDE3B pathway in mediating leptin (show LEP Antibodies) action in the hypothalamus.

  2. Suggest that by reducing production of cAMP in adipocytes, PDE3B, IKKepsilon (show IKBKE Antibodies) and TBK1 (show TBK1 Antibodies) may contribute to the repression of energy expenditure during obesity.

  3. Lack of PDE3B in brown adipocytes impairs the action of insulin (show INS Antibodies) on lipolysis.

  4. these findings indicate that PDE3B deletion confers cardioprotective effects because of cAMP/PKA-induced preconditioning, which is associated with the accumulation of proteins with cardioprotective function in ICEFs.

  5. Data suggest that Pde3b is involved in regulation of adipogenesis of adult stem cells into white adipocytes versus brown adipocytes; knockout mice lacking Pde3b form epididymal white adipose tissue with characteristics of brown adipose tissue.

  6. The variation of PDE3B-expression in the brain might play a crucial pathophysiological role, and regulation of PDE3B production might protect against ischemic brain damage.

  7. Calcineurin (show PPP3CA Antibodies) regulates degradation of phosphodiesterase 3B, in addition to phosphodiesterase 4D (show PDE4D Antibodies).

  8. The PDE3B pathway has a direct role in mediating leptin (show LEP Antibodies) signaling in proopiomelanocortin (show POMC Antibodies) and neuropeptide Y (show NPY Antibodies) neurons, via a potential mechanism of leptin (show LEP Antibodies) signaling in the hypothalamus.

  9. PDE3B and the anti-lipolytic action of insulin (show INS Antibodies) may have a role in increased S-nitrosylation of adipose tissue in obesity

  10. Results suggest that cav-1 (show CAV1 Antibodies) acts as a molecular chaperone (show HSP90AA1 Antibodies) or scaffolding molecule in cholesterol-rich lipid rafts that may be necessary for the proper stabilization and activation of PDE3B in response to CL and insulin (show INS Antibodies).

PDE3B Antigen Profile

Protein Summary

catalyzes the hydrolysis of cAMP and cGMP; regulates insulin secretory processes

Gene names and symbols associated with PDE3B

  • phosphodiesterase 3B, cGMP-inhibited (PDE3B) antibody
  • phosphodiesterase 3B, cGMP-inhibited (LOC100231533) antibody
  • phosphodiesterase 3B, cGMP-inhibited (pde3b) antibody
  • phosphodiesterase 3B, cGMP-inhibited (Pde3b) antibody
  • phosphodiesterase 3b, cGMP-inhibited (pde3b) antibody
  • 9830102A01Rik antibody
  • AI847709 antibody
  • cGIPDE1 antibody
  • HcGIP1 antibody
  • PDE3B antibody

Protein level used designations for PDE3B

phosphodiesterase 3B, cGMP-inhibited , cGMP-inhibited 3',5'-cyclic phosphodiesterase B-like , CGI-PDE B , CGIP1 , cGMP-inhibited 3',5'-cyclic phosphodiesterase B , cyclic GMP-inhibited phosphodiesterase B , cyclic nucleotide phosphodiesterase , CGIPDE1 , phosphodiesterase 3B cGMP inhibited

GENE ID SPECIES
611730 Canis lupus familiaris
698954 Macaca mulatta
100029160 Monodelphis domestica
100231533 Taeniopygia guttata
100352820 Oryctolagus cuniculus
100393923 Callithrix jacchus
100482771 Ailuropoda melanoleuca
100547369 Meleagris gallopavo
100556429 Anolis carolinensis
100600080 Nomascus leucogenys
5140 Homo sapiens
18576 Mus musculus
29516 Rattus norvegicus
563432 Danio rerio
496104 Xenopus laevis
423064 Gallus gallus
100516060 Sus scrofa
533323 Bos taurus
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