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anti-phosphodiesterase 8A (PDE8A) Antibodies

The protein encoded by PDE8A belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. Additionally we are shipping PDE8A Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDE8A 5151 O60658
PDE8A 18584 O88502
PDE8A 308776  
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Top anti-PDE8A Antibodies at antibodies-online.com

Showing 10 out of 69 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of PDE8A Antibody (Center) (L572) (ABIN388254) i... Formalin-fixed and paraffin-embedded human colon carcinoma tissue reac... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PDE8A Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... WB Suggested Anti-PDE8A  Antibody Titration: 0.2-1 µg/mL ELISA Titer: ... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated WB Western blotting analysis (reducing conditions) of PDE8a in HEK293T/17... 0.1 mg Log in to see 4 to 5 Days
$288.75
Details
Human Rabbit Un-conjugated IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ICC, IF ICC/IF Image PDE8A antibody detects PDE8A protein at cytoplasm by immu... 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IP, WB 0.1 mg Log in to see 6 to 8 Days
$456.50
Details
Dog Rabbit Un-conjugated IHC 0.05 mg Log in to see 2 to 3 Days
$481.25
Details
Human Rabbit Un-conjugated IP, ELISA, WB   100 μg Log in to see 8 to 10 Days
$859.83
Details

PDE8A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Mouse (Murine) , , , ,

Rat (Rattus) , , , ,

Top referenced anti-PDE8A Antibodies

  1. Human Polyclonal PDE8A Primary Antibody for WB - ABIN611116 : Aoki, Isselbacher, Pillai: Bruton tyrosine kinase is tyrosine phosphorylated and activated in pre-B lymphocytes and receptor-ligated B cells. in Proceedings of the National Academy of Sciences of the United States of America 1994 (PubMed)
    Show all 4 references for ABIN611116

  2. Human Polyclonal PDE8A Primary Antibody for EIA, IHC (p) - ABIN356970 : Wu, Wang: Per-Arnt-Sim domain-dependent association of cAMP-phosphodiesterase 8A1 with IkappaB proteins. in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 2 references for ABIN356970

  3. Human Monoclonal PDE8A Primary Antibody for WB - ABIN1690735 : Wang, Yan, Yang, Cai, Robinson, Ke: Kinetic and structural studies of phosphodiesterase-8A and implication on the inhibitor selectivity. in Biochemistry 2009 (PubMed)
    Show all 2 references for ABIN1690735

More Antibodies against PDE8A Interaction Partners

Human phosphodiesterase 8A (PDE8A) interaction partners

  1. PDE8A supports HIV-1 replication in macrophages

  2. PDE8A can bind tightly to Raf-1 (show RAF1 Antibodies), regulate Raf-1 (show RAF1 Antibodies) phosphorylation on S259, and, in so doing, regulate the cross-talk node whereby cAMP exerts an inhibitory effect on Raf-1 (show RAF1 Antibodies) signaling, retarding subsequent ERK (show EPHB2 Antibodies) phosphorylation and activation.

  3. PDE8 activity can be modulated by a kinase

  4. Polymorphism in PDE8A affects HIV-1 replication in primary macrophages.

  5. Comparison of enzymatic characterization and gene organization of PDE8B (show PDE8B Antibodies) and PDE8A.

  6. The findings exclude a significant role for PDE8A as a PCOS candidate gene, and as a Las (show LIAS Antibodies) major determinant of androgen levels in women.

Mouse (Murine) phosphodiesterase 8A (PDE8A) interaction partners

  1. findings suggest that both PDE8A and PDE8B (show PDE8B Antibodies) play essential roles to maintain low cAMP levels, thereby suppressing resting steroidogenesis by keeping CEH (show EPHX2 Antibodies)/HSL (show LIPE Antibodies) inactive and StAR protein expression low

  2. PDE8 as a novel target for suppression of Teff cell functions, including adhesion to endothelial cells

  3. PDE8A plays a critical role in the modulation of at least one compartment of cAMP and hence PKA activity during beta-adrenergic receptor (betaAR) activation in ventricular myocytes.

  4. pharmacological manipulation of PDE8A, alone or in combination with other PDEs present in Leydig cells, may be exploited to modulate testosterone synthesis

PDE8A Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PDE8A

  • phosphodiesterase 8A (PDE8A) antibody
  • phosphodiesterase 8a (Pde8a) antibody
  • phosphodiesterase 8A (pde8a) antibody
  • phosphodiesterase 8A (LOC100223556) antibody
  • phosphodiesterase 8A (LOC100343099) antibody
  • phosphodiesterase 8A (Pde8a) antibody
  • AI551852 antibody
  • HsT19550 antibody
  • Pde8 antibody
  • Pde8a antibody
  • RNPDE8A antibody

Protein level used designations for PDE8A

phosphodiesterase 8A , high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A , phosphodiesterase 8a , high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A-like , cAMP-specific cyclic nucleotide phosphodiesterase 8A , mmPDE8 , cAMP-specific cyclic nucleotide phosphodiesterase PDE8

GENE ID SPECIES
415455 Gallus gallus
453612 Pan troglodytes
488752 Canis lupus familiaris
506787 Bos taurus
694750 Macaca mulatta
100010222 Monodelphis domestica
100302670 Cavia porcellus
100456736 Pongo abelii
100497070 Xenopus (Silurana) tropicalis
100514527 Sus scrofa
100579512 Nomascus leucogenys
100223556 Taeniopygia guttata
100343099 Oryctolagus cuniculus
5151 Homo sapiens
18584 Mus musculus
308776 Rattus norvegicus
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