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PTPN11 antibody (Tyr580)
PTPN11
Reactivity: Human, Mouse, Rat
WB, IHC, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-PTPN11 Antibody
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Target
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PTPN11
(Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
Binding Specificity
All epitopes for PTPN11 antibodies
Tyr580
Reactivity
All reactivities for PTPN11 antibodies
Human, Mouse, Rat
Host
All hosts for PTPN11 antibodies
Rabbit
Clonality
All clonalities for PTPN11 antibodies
Polyclonal
Conjugate
All conjugates for PTPN11 antibodies
This PTPN11 antibody is un-conjugated
Application
All applications for PTPN11 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
Specificity
SHP-2 (Ab-580) antibody detects endogenous levels of total SHP-2 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Immunogen
The antiserum was produced against synthesized non-phosphopeptide derived from human SHP-2 around the phosphorylation site of tyrosine 580 (R-V-YP-E-N).
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1 mg/mL
Buffer
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Storage
-20 °C
Storage Comment
Store at -20°C / 1 year
Expiry Date
12 months
Target Details for PTPN11
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Target
PTPN11
(Protein tyrosine Phosphatase, Non-Receptor Type 11 (PTPN11))
Alternative Name
SHP-2 (PTPN11 Products )
Synonyms
BPTP3 antibody, CFC antibody, NS1 antibody, PTP-1D antibody, PTP2C antibody, SH-PTP2 antibody, SH-PTP3 antibody, SHP2 antibody, 2700084A17Rik antibody, AW536184 antibody, PTP1D antibody, SAP-2 antibody, SHP-2 antibody, Shp2 antibody, Syp antibody, SYP antibody, bptp3 antibody, cfc antibody, ns1 antibody, ptp-2 antibody, ptp2c antibody, ptpn11 antibody, ptpn11-a antibody, ptpn11-b antibody, shp-2 antibody, shp2 antibody, fa14b09 antibody, wu:fa14b09 antibody, wu:fi24f03 antibody, zgc:55388 antibody, zgc:63553 antibody, protein tyrosine phosphatase, non-receptor type 11 antibody, protein tyrosine phosphatase, non-receptor type 11 S homeolog antibody, protein tyrosine phosphatase, non-receptor type 11, a antibody, protein tyrosine phosphatase, non-receptor type 11, b antibody, PTPN11 antibody, Ptpn11 antibody, ptpn11.S antibody, ptpn11a antibody, ptpn11b antibody
Target Type
Viral Protein
Background
EC 3.1.3.48, PTN11, PTP-1D, PTP-2C, PTP2C, PTPN11, Protein-tyrosine phosphatase 2C, Protein-tyrosine phosphatase, non-receptor type 11, SH-PTP2, SH-PTP3, SHPTP2
UniProt
Q06124
Pathways
JAK-STAT Signaling , RTK Signaling , TCR Signaling , Interferon-gamma Pathway , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Negative Regulation of Hormone Secretion , Carbohydrate Homeostasis , Toll-Like Receptors Cascades , CXCR4-mediated Signaling Events , Signaling Events mediated by VEGFR1 and VEGFR2 , Signaling of Hepatocyte Growth Factor Receptor , VEGFR1 Specific Signals , BCR Signaling , Warburg Effect
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