IFNB1 antibody
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- Target See all IFNB1 Antibodies
- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
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Reactivity
- Pig
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IFNB1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA
- Specificity
- This product was protein A purified from monospecific antiserum by chomotography. This antibody is specific for swine IFN beta protein. A BLAST analysis was used to suggest cross-reactivity with IFN beta from swine, bat, bovine, horse, rhesus monkey, human, cat, chimpanzees, and ferret sources based on 100% homology with the immunizing sequence. Cross-reactivity with IFN beta from other sources has not been determined.
- Characteristics
- Type I interferons comprise a vast and growing group of IFN proteins. Homologous molecules to type I IFNs are found in many species, including all mammals, and some have been identified in birds, reptiles, amphibians and fish species. The mammalian types are designated IFN-alpha, IFN-beta, IFN-kappa, IFN-delta, IFN-epsilon, IFN-tau, IFN-omega, and IFN-zeta (also known as limitin). The IFN-beta proteins are produced in large quantities by fibroblasts. They have antiviral activity which is mainly involved in innate immune response. Two types of IFN-beta proteins have been described.
- Purification
- purified
- Sterility
- Sterile filtered
- Immunogen
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This protein A purified antibody was prepared from whole rabbit antiserum produced by repeated immunizations with a recombinant protein raised in yeast corresponding to 164 amino acids of the mature swine IFN beta protein.
Immunogen Type: RecombinantProtein - Isotype
- IgG
- Top Product
- Discover our top product IFNB1 Primary Antibody
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- Application Notes
- This protein A purified antibody is suitable for ELISA and Western blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately 19.5 kDa in size corresponding to swine IFN beta by western blotting in the appropriate cell lysate or extract.
- Comment
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Gene Name: IFN beta
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitution Buffer: Restore with deionized water (or equivalent), Reconstitution Volume: 100 µL
- Concentration
- 1.0 mg/mL
- Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store vial at 4 °C prior to restoration. For extended storage aliquot contents and freeze at -20 °C or below. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4 °C as an undiluted liquid. Dilute only prior to immediate use. Expiration date is one (1) year from date of opening.
- Expiry Date
- 12 months
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- Target
- IFNB1 (Interferon, beta 1, Fibroblast (IFNB1))
- Alternative Name
- Interferon Beta (IFNB1 Products)
- Synonyms
- IFB antibody, IFF antibody, IFNB antibody, IFN-beta antibody, Ifb antibody, Ifnb antibody, IFNb antibody, interferon beta 1 antibody, interferon beta 1, fibroblast antibody, interferon, beta 1, fibroblast antibody, IFNB1 antibody, Ifnb1 antibody
- Background
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Type I interferons comprise a vast and growing group of IFN proteins. Homologous molecules to type I IFNs are found in many species, including all mammals, and some have been identified in birds, reptiles, amphibians and fish species. The mammalian types are designated IFN-alpha, IFN-beta, IFN-kappa, IFN-delta, IFN-epsilon, IFN-tau, IFN-omega, and IFN-zeta (also known as limitin). The IFN-beta proteins are produced in large quantities by fibroblasts. They have antiviral activity which is mainly involved in innate immune response. Two types of IFN-beta proteins have been described.
Synonyms: Interferon-beta, interferon-beta/ poIFN-beta, IFN - Gene ID
- 445459
- NCBI Accession
- NP_001003923
- UniProt
- Q29412
- Pathways
- JAK-STAT Signaling, TCR Signaling, TLR Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Autophagy, Inflammasome
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