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anti-Rat (Rattus) Caspase 4 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended Caspase 4 Antibody (supplied by: Log in to see )

Antigen
Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antibodies
  • CASP4
  • ICE(rel)II
  • ICEREL-II
  • ICH-2
  • Mih1/TX
  • TX
  • Casp11
  • Caspl
  • ich-3
  • CASP1
  • CASP13
  • caspase 4
  • caspase 11
  • caspase 4, apoptosis-related cysteine peptidase
  • caspase-4-like
  • CASP4
  • LOC100101589
  • Casp4
  • LOC100359184
Reactivity
Human, Mouse (Murine), Rat (Rattus)
180
108
45
19
3
1
1
Host
Rabbit
185
30
21
16
6
Clonality
Polyclonal
Conjugate
This Caspase 4 antibody is un-conjugated
15
13
4
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
233
109
73
57
32
27
23
19
13
9
8
6
3
2
1
1
Supplier
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Catalog No. ABIN498677
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.159162 ABIN4288125 IHC IHC (p) WB Rabbit Log in to see Polyclonal
12.159162 ABIN872827 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN2893038 IHC (p) WB Rabbit Glu124 Log in to see Polyclonal
1 ABIN886623 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN2617985 IHC (p) WB Rabbit Internal Region Log in to see Polyclonal
1 ABIN886629 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal

Similar anti-Caspase 4 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Immunofluorescence (fixed cells) (IF/ICC) 3 Antibodies 3 Antibodies
Western Blotting (WB) 170 Antibodies 93 Antibodies 34 Antibodies
Microarray (MA) 5 Antibodies 4 Antibodies
Immunoprecipitation (IP) 13 Antibodies 5 Antibodies 7 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 54 Antibodies 36 Antibodies 7 Antibodies
Immunohistochemistry (IHC) 55 Antibodies 26 Antibodies 5 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 20 Antibodies 1 Antibodies

General

Antigen Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(180), (108), (45), (19), (3), (1), (1)
Host Rabbit
(185), (30), (21), (16), (6)
Clonality
Polyclonal
Conjugate This Caspase 4 antibody is un-conjugated
(15), (13), (4), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(233), (109), (73), (57), (32), (27), (23), (19), (13), (9), (8), (6), (3), (2), (1), (1)
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Product Details anti-Caspase 4 Antibody

Target Details Caspase 4 Application Details Handling Images
Specificity This antibody detects endogenous levels of Caspase-4 protein. (region surrounding Glu124)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Purity > 95 % by SDS-PAGE

Target Details Caspase 4

Product Details anti-Caspase 4 Antibody Application Details Handling Images back to top
Antigen
Alternative Name Caspase-4 (CASP4 Antibody Abstract)
Background A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed Ced-3/caspase-1, is comprised of caspase- 1, caspase-2, caspase-3, caspase-4, caspase-6 and caspase-7 (also designated Mch3, ICE-LAP3 or CMH-1), caspase-9, and caspase-10. Ced- 3/caspase-1 family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Poly(ADP-ribose) polymerase plays an integral role in surveying for DNA mutations and double strand breaks. Caspase-3, caspase-7 and caspase-9, but not caspase-1, have been shown to cleave the 112 kDa nuclear protein PARP into an 85 kDa apoptotic fragment. Caspase-6, but not caspase-3, has been shown to cleave the nuclear lamins which are critical to maintaining the integrity of the nuclear envelope and cellular morphology. Caspase-10 has been shown to activate caspase-3 and caspase-7 in response to apoptotic stimuli.Synonyms: CASP4, ICE(rel)-II, ICH2, Protease ICH-2, Protease TX
Molecular Weight approx. 34 kDa
Gene ID 837
NCBI Accession NP_001216
UniProt P49662
Research Area Apoptosis/Necrosis
Pathways Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Handling Images back to top
Application Notes Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Images

Product Details anti-Caspase 4 Antibody Target Details Caspase 4 Application Details Handling back to top
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Caspase 4 antibody (Caspase 4, Apoptosis-Related Cysteine Peptidase) (ABIN498677) Immunohistochemistry (IHC) analyzes of Caspase-4 antibody in paraffin-embedded...
Western Blotting (WB) image for anti-Caspase 4 antibody (Caspase 4, Apoptosis-Related Cysteine Peptidase) (ABIN498677) Western blot (WB) analyzes of Caspase-4 antibody in extracts from K562 cells.