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Browse our anti-Polymerase (DNA Directed) kappa (POLK) Antibodies

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anti-Polymerase (DNA Directed) kappa Antibodies (POLK)
On are 80 Polymerase (DNA Directed) kappa (POLK) Antibodies from 13 different suppliers available. Additionally we are shipping Polymerase (DNA Directed) kappa Proteins (5) and many more products for this protein. A total of 94 Polymerase (DNA Directed) kappa products are currently listed.
Dinb1, DINP, DKFZp459J211, LAK-1, POLK, POLQ, Pols, si:ch211-254o18.3, TRF4, TRF4-1
list all antibodies Gene Name GeneID UniProt
POLK 210106 Q6PB75
POLK 51426 Q9UBT6
POLK 171525  

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Most Popular Reactivities for anti-Polymerase (DNA Directed) kappa (POLK) Antibodies

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anti-Mouse (Murine) Antibodies:

anti-Human Antibodies:

anti-Rat (Rattus) Antibodies:

All available anti-Polymerase (DNA Directed) kappa Antibodies

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Top referenced anti-Polymerase (DNA Directed) kappa Antibodies

  1. Human Polyclonal POLK Primary Antibody for WB - ABIN1881669 : Lone, Townson, Uljon, Johnson, Brahma, Nair, Prakash, Prakash, Aggarwal: Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. in Molecular cell 2007 (PubMed)
    Show all 5 references for ABIN1881669

  2. Cow (Bovine) Polyclonal POLK Primary Antibody for WB - ABIN2783506 : Hile, Eckert: DNA polymerase kappa produces interrupted mutations and displays polar pausing within mononucleotide microsatellite sequences. in Nucleic acids research 2008 (PubMed)

  3. Human Monoclonal POLK Primary Antibody for IF, IHC (p) - ABIN565606 : Sekimoto, Oda, Kurashima, Hanaoka, Yamashita: Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication. in Molecular and cellular biology 2015 (PubMed)

More Antibodies against Polymerase (DNA Directed) kappa Interaction Partners

Mouse (Murine) Polymerase (DNA Directed) kappa (POLK) interaction partners

  1. Polk plays a predominant role in suppressing point mutations by carrying out error-free translesion DNA synthesis and contributes to the prevention of DNA strand breaks.

  2. The structural gap physically accommodates the bulky aromatic adduct and the N-clasp (show CLASRP Antibodies) is essential for the structural integrity and flexibility of Polkappa (show POLL Antibodies) during translesion synthesis.

  3. Polkappa (show POLL Antibodies) accumulates at laser-induced sites of DNA damage.

  4. Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric polymerase (Pol) zeta, and Pol kappa (show POLL Antibodies)

  5. Data suggest that DNA polymerase kappa Polkapp (show POLL Antibodies)a functions in DNA interstrand crosslinks (ICLs) repair in (show APBB1 Antibodies) embryonic fibroblast cells (MEF), especially during the G0/G1 phases.

  6. solution structure of the polymerase kappa-Rev1 complex

  7. results are consistent with the notion that Pol kappa (show POLL Antibodies) is required for accurate translesion DNA synthesis past naturally occurring polycyclic guanine adducts, possibly generated by cholesterol and/or its metabolites.

  8. Polkappa (show POLL Antibodies) plays an important role in suppressing mutations at DNA lesions generated by benzo[a]pyrene, but not UV or x-ray irradiation.

  9. Rev7 competes directly with Pol kappa for binding to the Rev1 C-terminus.

  10. The multiple mouse/human (PolK/POLK) transcripts may encode multiple Polkappa (show POLL Antibodies) isoforms in testis

Human Polymerase (DNA Directed) kappa (POLK) interaction partners

  1. POLK (show PAPD7 Antibodies) protein polymorphisms may influence the risk of developing breast cancer among Chinese women.

  2. Somatic Mutations in Catalytic Core of POLK (show PAPD7 Antibodies) Reported in Prostate Cancer Alter Translesion DNA Synthesis

  3. POLK (show PAPD7 Antibodies) not only protects cells from genotoxic DNA lesions via DNA polymerase (show POLB Antibodies) activities, but also contributes to genome integrity by acting as a non-catalytic protein against oxidative damage caused by hydrogen peroxide and menadione.

  4. The structural dynamics of DinB1 changes upon substrate binding, noncognate DNA damage prevents the formation of the active conformation of DINB1.

  5. polymorphism of POLK (show PAPD7 Antibodies), an important gene in TLS (show FUS Antibodies), participates in platinum-chemotherapy tolerance and side-effect

  6. Mutations in PIP1 (show PAK1IP1 Antibodies) domain inhibits the stimulation of DNA synthesis by Polkappa (show POLL Antibodies) in the presence of proliferating cell nuclear antigen (show PCNA Antibodies), replication factor C, and replication protein A (show GPR153 Antibodies); and mutations in PIP2 have no effect on PCNA (show PCNA Antibodies)-dependent DNA synthesis.

  7. The truncation R219X was devoid of polymerase activity, and the E419G and Y432S variants showed much lower polymerase activity than wild-type POLK (show PAPD7 Antibodies).

  8. role of the unique Polkappa (show POLL Antibodies) gap and N-clasp (show CLASRP Antibodies) structural features in the fidelity of minor groove lesion processing with extensive molecular modeling and molecular dynamics simulations to pinpoint their functioning in lesion bypass

  9. Phenylalanine 171 is used by PolK (show PAPD7 Antibodies) as a molecular brake for translesional synthesis across benzo[a]pyrene DNA adducts.

  10. DNA polymerase kappa (show PAPD7 Antibodies) rs5744724 polymorphism is associated with lung cancer.

Xenopus laevis Polymerase (DNA Directed) kappa (POLK) interaction partners

  1. DNA polymerase kappa-dependent DNA synthesis at stalled replication forks is important for CHK1 (show CHEK1 Antibodies) activation.

  2. Data show that DNA polymerase kappa (Pol kappa (show POLL Antibodies)) is essential for replication-independent ICL repair (RIR (show APBB1 Antibodies)) of a site-specific DNA interstrand crosslinks (ICLs) lesion.

  3. pol kappa (show POLL Antibodies) (translesion synthesis TLS4) may assist pol eta (TLS3 or Rad30 (show POLH Antibodies)) in error-free extension during cyclobutane pyrimidine dimer bypass during DNA replication in oocyte extracts.

Polymerase (DNA Directed) kappa (POLK) Antigen Profile

Antigen Summary

External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007

Alternative names and synonyms associated with Polymerase (DNA Directed) kappa (POLK)

  • polymerase (DNA directed) kappa (POLK) antibody
  • polymerase (DNA directed) kappa (polk) antibody
  • DNA polymerase kappa (Tb11.01.0080) antibody
  • DNA polymerase kappa (Tb11.01.0010) antibody
  • DNA polymerase kappa (Tb11.01.0020) antibody
  • DNA polymerase kappa (Tb11.01.0030) antibody
  • DNA polymerase kappa (Tb11.01.0040) antibody
  • DNA polymerase kappa (Tb11.01.0050) antibody
  • DNA polymerase kappa (Tb11.12.0001) antibody
  • DNA polymerase kappa (Tb11.12.0002) antibody
  • DNA polymerase kappa (Tb11.12.0003) antibody
  • PAP associated domain containing 7 (Papd7) antibody
  • polymerase (DNA directed) kappa (Polk) antibody
  • polymerase (DNA directed), kappa (Polk) antibody
  • Dinb1 antibody
  • DINP antibody
  • DKFZp459J211 antibody
  • LAK-1 antibody
  • POLK antibody
  • POLQ antibody
  • Pols antibody
  • si:ch211-254o18.3 antibody
  • TRF4 antibody
  • TRF4-1 antibody

Protein level used designations for POLK

DNA polymerase kappa , DNA-directed DNA polymerase kappa , polymerase (DNA directed) kappa , DNA polymerase kappa-like , DNA polymerase sigma , PAP-associated domain-containing protein 7 , polymerase (DNA directed) sigma , DINB protein , DINP , DNA damage-inducible protein b , DinB homolog 1

374003 Gallus gallus
448219 Xenopus (Silurana) tropicalis
705713 Macaca mulatta
3665078 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665080 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665081 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665082 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665083 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665084 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665087 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665088 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665089 Trypanosoma brucei brucei strain 927/4 GUTat10.1
100014509 Monodelphis domestica
100065534 Equus caballus
100077423 Ornithorhynchus anatinus
100173466 Pongo abelii
100352218 Oryctolagus cuniculus
100403269 Callithrix jacchus
100464732 Ailuropoda melanoleuca
562749 Danio rerio
210106 Mus musculus
51426 Homo sapiens
479180 Canis lupus familiaris
541218 Bos taurus
171525 Rattus norvegicus
461803 Pan troglodytes
100443121 Pongo abelii
446387 Xenopus laevis
100518650 Sus scrofa
27015 Mus musculus
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