GADD45A Protein (AA 1-165) (His tag)
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- Target See all GADD45A Proteins
- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-165
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GADD45A protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- GADD45A, 1-165aa, Human, His tag, E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product GADD45A Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl
- Storage
- 4 °C
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- Target
- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
- Alternative Name
- GADD45A (GADD45A Products)
- Synonyms
- MGC53491 Protein, zgc:91795 Protein, gadd45a Protein, GADD45A Protein, ddit1 Protein, gadd45 Protein, GADD45 Protein, AA545191 Protein, Ddit1 Protein, DDIT1 Protein, Gadd45 Protein, growth arrest and DNA damage inducible alpha L homeolog Protein, growth arrest and DNA-damage-inducible, alpha, b Protein, growth arrest and DNA damage inducible alpha Protein, growth arrest and DNA damage-inducible protein 45 Protein, growth arrest and DNA-damage-inducible 45 alpha Protein, growth arrest and DNA-damage-inducible, alpha Protein, gadd45a.L Protein, gadd45ab Protein, GADD45A Protein, gadd45a Protein, GADD45 Protein, Gadd45a Protein
- Background
- GADD45A, also known as growth arrest and DNA damage-inducible protein, binds both Cdks and PCNA, a protein involved in DNA replication and repair. It has been shown to stimulate DNA excision repair in vitro and to inhibit entry of cells into S phase. This protein may serve as a link between p53-dependent cell cycle checkpoint and DNA repair. Recombinant human GADD45A protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DDIT1, GADD45, Growth arrest and DNA damage-inducible protein GADD45 alpha DDIT 1, DNA damage inducible transcript 1, Growth arrest and DNA damage inducible 45 alpha,. NCBI no.: NP_001915
- Molecular Weight
- 19.4 kDa (173aa), confirmed by MALDI-TOF
- Pathways
- p53 Signaling, Cell Division Cycle
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