GADD45A Protein (AA 1-165, full length) (His-SUMO Tag)
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- Target See all GADD45A Proteins
- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-165
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GADD45A protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MTLEEFSAGE QKTERMDKVG DALEEVLSKA LSQRTITVGV YEAAKLLNVD PDNVVLCLLA ADEDDDRDVA LQIHFTLIQA FCCENDINIL RVSNPGRLAE LLLLETDAGP AASEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES RYMDQWVPVI NLPER
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product GADD45A Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
- Alternative Name
- GA45A (GADD45A Products)
- Synonyms
- MGC53491 Protein, zgc:91795 Protein, gadd45a Protein, GADD45A Protein, ddit1 Protein, gadd45 Protein, GADD45 Protein, AA545191 Protein, Ddit1 Protein, DDIT1 Protein, Gadd45 Protein, growth arrest and DNA damage inducible alpha L homeolog Protein, growth arrest and DNA-damage-inducible, alpha, b Protein, growth arrest and DNA damage inducible alpha Protein, growth arrest and DNA damage-inducible protein 45 Protein, growth arrest and DNA-damage-inducible 45 alpha Protein, growth arrest and DNA-damage-inducible, alpha Protein, gadd45a.L Protein, gadd45ab Protein, GADD45A Protein, gadd45a Protein, GADD45 Protein, Gadd45a Protein
- Background
- In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity . Might affect PCNA interaction with some CDK (cell division protein kinase) complexes, stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
- Molecular Weight
- 34.3 kDa
- UniProt
- P24522
- Pathways
- p53 Signaling, Cell Division Cycle
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