GADD45A Protein (AA 1-165, full length) (His-SUMO Tag)
Quick Overview for GADD45A Protein (AA 1-165, full length) (His-SUMO Tag) (ABIN5709547)
Target
See all GADD45A ProteinsProtein Type
Origin
Source
Application
Purity
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Protein Characteristics
- full length, AA 1-165
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Purification tag / Conjugate
- This GADD45A protein is labelled with His-SUMO Tag.
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Sequence
- MTLEEFSAGE QKTERMDKVG DALEEVLSKA LSQRTITVGV YEAAKLLNVD PDNVVLCLLA ADEDDDRDVA LQIHFTLIQA FCCENDINIL RVSNPGRLAE LLLLETDAGP AASEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES RYMDQWVPVI NLPER
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Purification
- SDS-PAGE
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Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) protein (His tag)
custom-made GADD45A Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) protein (His tag)custom-made GADD45A Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) protein (GST tag)GADD45A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.1-2 mg/mL
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Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
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Storage
- -80 °C,4 °C,-20 °C
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Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
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Alternative Name
- GA45A
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Background
- In T-cells, functions as a regulator of p38 MAPKs by inhibiting p88 phosphorylation and activity . Might affect PCNA interaction with some CDK (cell division protein kinase) complexes, stimulates DNA excision repair in vitro and inhibits entry of cells into S phase.
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Molecular Weight
- 34.3 kDa
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UniProt
- P24522
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Pathways
- p53 Signaling, Cell Division Cycle
Target
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