GADD45A Protein (Myc-DYKDDDDK Tag)
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- Target See all GADD45A Proteins
- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This GADD45A protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human GADD45A protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GADD45A Protein
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Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) protein (GST tag)
GADD45A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 76-165) protein (GST tag)GADD45A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) protein (Strep Tag)Crystallography grade GADD45A Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) protein (Strep Tag)Crystallography grade GADD45A Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165), (full length) protein (His-SUMO Tag)GADD45A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
- Alternative Name
- Gadd45a (GADD45A Products)
- Synonyms
- MGC53491 Protein, zgc:91795 Protein, gadd45a Protein, GADD45A Protein, ddit1 Protein, gadd45 Protein, GADD45 Protein, AA545191 Protein, Ddit1 Protein, DDIT1 Protein, Gadd45 Protein, growth arrest and DNA damage inducible alpha L homeolog Protein, growth arrest and DNA-damage-inducible, alpha, b Protein, growth arrest and DNA damage inducible alpha Protein, growth arrest and DNA damage-inducible protein 45 Protein, growth arrest and DNA-damage-inducible 45 alpha Protein, growth arrest and DNA-damage-inducible, alpha Protein, gadd45a.L Protein, gadd45ab Protein, GADD45A Protein, gadd45a Protein, GADD45 Protein, Gadd45a Protein
- Background
- This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010].
- Molecular Weight
- 18.2 kDa
- NCBI Accession
- NP_001915
- Pathways
- p53 Signaling, Cell Division Cycle
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