GADD45A Protein (Myc-DYKDDDDK Tag)
Quick Overview for GADD45A Protein (Myc-DYKDDDDK Tag) (ABIN2721553)
Target
See all GADD45A ProteinsProtein Type
Origin
Source
Application
Purity
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Purification tag / Conjugate
- This GADD45A protein is labelled with Myc-DYKDDDDK Tag.
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Characteristics
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- Recombinant human GADD45A protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) protein (His tag)
custom-made GADD45A Origin: Mouse Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) protein (His tag)custom-made GADD45A Origin: Human Host: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (AA 1-165) protein (GST tag)GADD45A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
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Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Comment
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Storage
- -80 °C
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Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
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Alternative Name
- Gadd45a
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Background
- This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Dec 2010].
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Molecular Weight
- 18.2 kDa
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NCBI Accession
- NP_001915
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Pathways
- p53 Signaling, Cell Division Cycle
Target
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