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GADD45A Protein (AA 1-165) (His tag)

GADD45A Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN666990
  • Target See all GADD45A Proteins
    GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-165
    Origin
    • 8
    • 2
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This GADD45A protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    GADD45A, 1-165aa, Human, His tag, E.coli
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product GADD45A Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol, 0.1M NaCl
    Storage
    4 °C
  • Target
    GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
    Alternative Name
    GADD45A (GADD45A Products)
    Synonyms
    MGC53491 Protein, zgc:91795 Protein, gadd45a Protein, GADD45A Protein, ddit1 Protein, gadd45 Protein, GADD45 Protein, AA545191 Protein, Ddit1 Protein, DDIT1 Protein, Gadd45 Protein, growth arrest and DNA damage inducible alpha L homeolog Protein, growth arrest and DNA-damage-inducible, alpha, b Protein, growth arrest and DNA damage inducible alpha Protein, growth arrest and DNA damage-inducible protein 45 Protein, growth arrest and DNA-damage-inducible 45 alpha Protein, growth arrest and DNA-damage-inducible, alpha Protein, gadd45a.L Protein, gadd45ab Protein, GADD45A Protein, gadd45a Protein, GADD45 Protein, Gadd45a Protein
    Background
    GADD45A, also known as growth arrest and DNA damage-inducible protein, binds both Cdks and PCNA, a protein involved in DNA replication and repair. It has been shown to stimulate DNA excision repair in vitro and to inhibit entry of cells into S phase. This protein may serve as a link between p53-dependent cell cycle checkpoint and DNA repair. Recombinant human GADD45A protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DDIT1, GADD45, Growth arrest and DNA damage-inducible protein GADD45 alpha DDIT 1, DNA damage inducible transcript 1, Growth arrest and DNA damage inducible 45 alpha,. NCBI no.: NP_001915
    Molecular Weight
    19.4 kDa (173aa), confirmed by MALDI-TOF
    Pathways
    p53 Signaling, Cell Division Cycle
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