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Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Additionally we are shipping and Large Neutral Amino Acid Transporter 3 Proteins (1) and many more products for this protein.
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Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires co-expression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.
Y+L amino acid transporter 2
, amino acid permease
, cationic amino acid transporter, y+ system
, solute carrier family 7 (cationic amino acid transporter, y+ system), member 6
, solute carrier family 7 member 6
, y(+)L-type amino acid transporter 2