Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Additionally we are shipping MMP8 Antibodies (183) and MMP8 Kits (106) and many more products for this protein.
Showing 10 out of 23 products:
MMP8 plays an important role in intestinal I/R injury through mechanisms involving increased inflammation and loss of claudin-3 (show CLDN3 Proteins)
These results suggest that some of the anti-inflammatory effects of Dexamethasone are mediated through increased MMP-8 expression.
These results suggest a novel pathogenetic role of MMP8 and implicate modulation of its activity as a tractable strategy for therapies against cerebral ischemia.
Fusion peptide inhibitors of MMP-8/-9 prevent endotoxic shock if administered within a strict time window.
the loss of MMP-8 likely has pleiotropic effects on innate immunity and angiogenesis that are reflected in changes in the protease web.
A previously unknown role of MMP8 in M2-macrophage polarization by cleaving fibromodulin (show FMOD Proteins) and therefore increasing the bioavailability of TGF-beta (show TGFB1 Proteins).
MMP-8-deficient mice had significantly lower serum triglyceride (TG) levels (P = 0.003) and larger HDL (show HSD11B1 Proteins) particles compared with wild-type (WT) mice. However, no differences were observed in the apoA-I (show APOA1 Proteins) levels.
These results demonstrate that MMP-8 critically mediates microglial activation by modulating TNF-alpha (show TNF Proteins) activity, which may explain neuroinflammation in septic mouse brain.
MMP-13 (show MMP13 Proteins) prevails over MMP-8 in collagen degradation in atheromata.
MMP8 enhances vascular smooth muscle cell proliferation via an ADAM10 (show ADAM10 Proteins), N-cadherin (show CDH2 Proteins), and beta-catenin (show CTNNB1 Proteins)-mediated pathway and plays an important role in neointima formation.
The serum levels of IL-8 (show IL8 Proteins), MIP-1 alpha (show CCL3 Proteins), MIP-1 beta (show CCL4 Proteins), MMP-8, Resistin (show RETN Proteins), FLRG (show FSTL3 Proteins), and BCAM (show BCAT2 Proteins) were significantly higher in breast cancer patients, but LAP and TSH-beta (show TSHB Proteins) levels were lower.
Matrix metalloproteinase-1 (show MMP1 Proteins), -8, -9 and the risk of cardiovascular complications in patients with CHD (show CHDH Proteins) before and after myocardial revascularization.
Our study provides evidence for the tumour-suppressive mechanisms of MMP-8 in OTSCC by interplay with TGF-b1 and VEGF-C (show VEGFC Proteins).
These results provide the first evidence that MMP8 SNP at the rs11225394 locus is associated with the increased risk of osteonecrosis of the femoral head in Chinese Han population.
Low MMP-8/TIMP-1 (show TIMP1 Proteins) reflects left ventricle impairment in takotsubo cardiomyopathy and high TIMP-1 (show TIMP1 Proteins) may help to differentiate it from acute coronary syndrome
Plasma levels of MMP-1 (show MMP1 Proteins), MMP-8, and MMP-9 (show MMP9 Proteins) are associated with COPD (show ARCN1 Proteins) severity and can be used as a biomarker to better understand the characteristics of COPD (show ARCN1 Proteins) patients.
there is a negative correlation between blood MMP8 and HDL (show HSD11B1 Proteins)-cholesterol levels, suggesting a contributory role of MMP8 in metabolic alterations in acne inversa
plasma concentrations of MMP-7 (show MMP7 Proteins), MMP-8, -9 and TIMP-1 (show TIMP1 Proteins) within 96 h from the onset of acute pancreatitis symptoms are elevated in acute pancreatitis patients compared with healthy controls
MMP-8 is a vital component of the myoepithelial tumour-suppressor function. It restores MEC (show CCL28 Proteins) interaction with the matrix, opposes TGF-beta (show TGFB1 Proteins) signalling and MMP-9 (show MMP9 Proteins) proteolysis, which contributes to inhibition of tumour cell invasion.
a 7-gene signature was identified which correctly predicted the primary prefibrotic myelofibrosis group with a sensitivity of 100% and a specificity of 89%. The 7 genes included MPO (show MPO Proteins), CEACAM8, CRISP3 (show CRISP3 Proteins), MS4A3 (show MS4A3 Proteins), CEACAM6, HEMGN, and MMP8
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
matrix metallopeptidase 8 (neutrophil collagenase)
, matrix metalloproteinase 8
, collagenase 2
, matrix metalloproteinase-8
, neutrophil collagenase
, neutrophil collagenease
, PMNL collagenase
, matrix metalloproteinase 8 (neutrophil collagenase)