anti-Programmed Cell Death 1 (PDCD1) Antibodies

May have a role in the regulation of spermatogenesis.. Additionally we are shipping PD-1 Proteins (93) and PD-1 Kits (24) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PDCD1 5133 Q15116
PDCD1 301626  
PDCD1 18566 Q02242
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Top anti-PD-1 Antibodies at antibodies-online.com

Showing 10 out of 659 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated BR, FACS   0.5 mg Log in to see 6 to 8 Days
$271.98
Details
Mouse Armenian Hamster Un-conjugated BR, FACS, IP   0.1 mg Log in to see 6 to 8 Days
$163.12
Details
Human Goat Un-conjugated BR, CyTOF, ELISA (Capture), FACS, IHC, WB Detection of Human PD-1 by Western Blot. Western blot shows lysate of human thymus tissue. PVDF membrane was probed with 2 ug/mL of Goat Anti-Human PD-1 Antigen Affinity-purified Polyclonal Antibody. This experiment was conducted under reducing conditions. PD-1 in Human Lymph Node. PD-1 was detected in immersion fixed paraffin-embedded sections of human lymph node using Goat Anti-Human PD-1 Antigen Affinity-purified Polyclonal Antibody  at 3 ug/mL overnight at 4 ᄚC. Tissue was stained using the Anti-Goat HRP-DAB Cell & 100 μg Log in to see 8 to 9 Days
$463.45
Details
Human Goat Un-conjugated ELISA, WB ABIN185400 (0.6µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 6 to 7 Days
$358.02
Details
Human Goat Biotin ELISA (Detection), FACS, WB Detection of PD-1 in Human PBMCs treated with PHA by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with 5 ug/mL PHA overnight were stained with Goat Anti-Human PD-1 Biotinylated Antigen Affinity-purified Polyclonal Antibody. 50 μg Log in to see 8 to 9 Days
$451.95
Details
Human Rabbit Un-conjugated WB Anti-PD1 Picoband antibody ,  All lanes: Anti PD1  at 0.5ug/ml Lane 1: JURKAT Whole Cell Lysate at 40ug Lane 2: Human Placenta Tissue Lysate at 50ug Predicted bind size: 32KD Observed bind size: 38KD Anti-PD1 Picoband antibody ,  All lanes: Anti PD1  at 0.5ug/ml WB: Recombinant Human PD1 Protein 0.5ng Predicted bind size: 38KD Observed bind size: 38KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Mouse Goat PE FACS Detection of PD-1 in Mouse CD4+ T-Cells by Flow Cytometry. Mouse CD4+ T-cells were stained with Goat Anti-Mouse PD-1 PE-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Log in to see 8 to 9 Days
$351.90
Details
Human Rabbit Un-conjugated WB Western blot analysis of CD279 expression in THP1 (A), HepG2 (B), mouse liver (C), H9C2 (D) whole cell lysates. 200 μL Log in to see 13 to 14 Days
$487.50
Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Mouse Un-conjugated CyTOF, FACS, WB Detection of PD-1 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclear cells (PBMCs) either (A) untreated or (B) treated with 5 ng/mL PHA for 2 days were stained with Mouse Anti-Human PD-1 Monoclonal Antibody. Detection of Human PD-1 by Western Blot. Western blot shows lysates of HEK293 human embryonic kidney cell line either mock transfected or transfected with human PD-1. PVDF membrane was probed with 1 ug/mL of Mouse Anti-Human PD-1 Monoclonal Antibody. This experiment was conducted under reducing conditions. 100 μg Log in to see 8 to 9 Days
$346.15
Details

PDCD1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PD-1 Antibodies

  1. Human Polyclonal PD-1 Primary Antibody for BR, CyTOF - ABIN5012979 : Wan, Nie, Liu, Feng, He, Xu, Zhang, Dong, Zhang: Aberrant regulation of synovial T cell activation by soluble costimulatory molecules in rheumatoid arthritis. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 11 Pubmed References

  2. Human Polyclonal PD-1 Primary Antibody for ELISA (Detection), FACS - ABIN4899871 : Sakthivel, Ramanujam, Wang, Pirskanen, Lefvert: Programmed Death-1: from gene to protein in autoimmune human myasthenia gravis. in Journal of neuroimmunology 2008 (PubMed)
    Show all 9 Pubmed References

  3. Human Monoclonal PD-1 Primary Antibody for BR, FACS - ABIN2689142 : Bennett, Luxenberg, Ling, Wang, Marquette, Lowe, Khan, Veldman, Jacobs, Valge-Archer, Collins, Carreno: Program death-1 engagement upon TCR activation has distinct effects on costimulation and cytokine-driven proliferation: attenuation of ICOS, IL-4, and IL-21, but not CD28, IL-7, and IL-15 responses. in Journal of immunology (Baltimore, Md. : 1950) 2003 (PubMed)
    Show all 8 Pubmed References

  4. Mouse (Murine) Monoclonal PD-1 Primary Antibody for BR, FACS - ABIN2689141 : Nishimura, Agata, Kawasaki, Sato, Imamura, Minato, Yagita, Nakano, Honjo: Developmentally regulated expression of the PD-1 protein on the surface of double-negative (CD4-CD8-) thymocytes. in International immunology 1997 (PubMed)
    Show all 7 Pubmed References

  5. Human Polyclonal PD-1 Primary Antibody for IHC, ELISA - ABIN1002980 : Holling, Schooten, van Den Elsen: Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. in Human immunology 2004 (PubMed)
    Show all 4 Pubmed References

  6. Human Polyclonal PD-1 Primary Antibody for IHC, ELISA - ABIN1002981 : Ishida, Agata, Shibahara, Honjo: Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death. in The EMBO journal 1992 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal PD-1 Primary Antibody for ICC, FACS - ABIN438813 : Dorrell, Abraham, Lanxon-Cookson, Canaday, Streeter, Grompe: Isolation of major pancreatic cell types and long-term culture-initiating cells using novel human surface markers. in Stem cell research 2009 (PubMed)
    Show all 3 Pubmed References

  8. Mouse (Murine) Polyclonal PD-1 Primary Antibody for CyTOF, FACS - ABIN4899873 : Kasagi, Kawano, Okazaki, Honjo, Morinobu, Hatachi, Shimatani, Tanaka, Minato, Kumagai: Anti-programmed cell death 1 antibody reduces CD4+PD-1+ T cells and relieves the lupus-like nephritis of NZB/W F1 mice. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal PD-1 Primary Antibody for IF (p), IHC (p) - ABIN735608 : Zhang, Niyazi, Hong, Tuluwengjiang, Zhang, Zhang, Su, Bao: Effect of EBI3 on radiation-induced immunosuppression of cervical cancer HeLa cells by regulating Treg cells through PD-1/PD-L1 pathway. in Tumour biology 2017 (PubMed)
    Show all 2 Pubmed References

  10. Human Monoclonal PD-1 Primary Antibody for FACS - ABIN2479653 : Ochonisky, Chosidow, Kuentz, Man, Fraitag, Pelisse, Revuz: Cogan's syndrome. An unusual etiology of urticarial vasculitis. in Dermatologica 1992 (PubMed)
    Show all 3 Pubmed References

More Antibodies against PD-1 Interaction Partners

Human Programmed Cell Death 1 (PDCD1) interaction partners

  1. These results demonstrate the involvement of sPD (show HOXD13 Antibodies)-1 in the disease course of chronic HBV infection and indicate the potential to apply sPD (show HOXD13 Antibodies)-1 as a biomarker for differentiating IT from other phases and HCC (show FAM126A Antibodies) from other disease conditions in chronic HBV infection.

  2. summarizes the latest research on PD-1 in infectious diseases and discusses its role in acute and chronic viral infection[review]

  3. Our study demonstrates a cross-talk between PARPi and tumor-associated immunosuppression and provides evidence to support the combination of PARPi and PD-L1 (show CD274 Antibodies) or PD-1 immune checkpoint blockade as a potential therapeutic approach to treat breast cancer

  4. Results show that high programmed cell death 1 (PDCD1, PD-1)methylation (mPDCD1) was associated with a significantly shorter overall survival after surgical resection.

  5. Suggest that genetic polymorphisms of PD-1 function as sex-dependent risk factors for development of acute rejection in an Iranian kidney transplant population.

  6. downregulation in PD-1 inhibitory signaling in RA could be attributed to increased serum sPD (show HOXD13 Antibodies)-1 and decreased synovial tissue PD-L1 (show CD274 Antibodies) levels

  7. PD1 polymorphisms are associated with susceptibility to chronic hepatitis B infection in the Chinese population.

  8. PD-1 seems to correlate with disease progression in epitheliotropic T cell dyscrasias ranging from minimal staining in prelymphomatous dyscrasias to significant staining in mycosis fungoides

  9. in some tumor types, PD-L2 (show PDCD1LG2 Antibodies) expression is more closely linked to Th1 (show TH1L Antibodies)/IFNG (show IFNG Antibodies) expression and PD-1 and CD8 (show CD8A Antibodies) signaling than PD-L1 (show CD274 Antibodies)

  10. Although mutational and immunologic differences have been proposed as the primary determinants of heterogeneous response/resistance to targeted therapies and immunotherapies, respectively, differential lesional gene expression profiles may also dictate anti-PD-1 outcomes

Mouse (Murine) Programmed Cell Death 1 (PDCD1) interaction partners

  1. An examination of the mechanisms of immunity behind this long-term protection in PD-1 knockout mice showed a key role for parasite-specific CD8 (show CD8A Antibodies)(+) T cells even when CD4 (show CD4 Antibodies)(+) T cells and B cells responded to re-infection.

  2. To test the in vivo activity of REGN2810, which does not cross-react with murine PD-1, knock-in mice were generated to express a hybrid protein containing the extracellular domain of human PD-1, and transmembrane and intracellular domains of mouse PD-1

  3. The combination of tumor vaccination to induce high avidity tumor specific T cell responses and PD-1 blockade synergises to provide tumor therapy and 85% survival in the aggressive B16 melanoma model.

  4. Blockade of PD-1 with monoclonal antibody may be an effective treatment during the postoperative period for restoring surgery-induced immunosuppression.

  5. Data suggest that genetic or environmental factors that even moderately affect the expression of both PD-1 and FoxP3 (show FOXP3 Antibodies) can cause life-threatening autoimmune diseases by disrupting the T-cell homeostasis.

  6. Data (including data from studies in transgenic/knockout mice) suggest that T-cell expression of Mirn155 is required to limit melanoma growth; miR (show MLXIP Antibodies)-155, Pdcd1, Pdcd1l1 (show CD274 Antibodies), and Ctla4 (show CTLA4 Antibodies) appear to regulate overlapping pathways promoting antitumor immunity. [Mirn155 = microRNA 155; Pdcd1 = programmed cell death 1 protein; Pdcd1l1 (show CD274 Antibodies) = programmed cell death 1 ligand 1 (show CD274 Antibodies) protein; Ctla4 (show CTLA4 Antibodies) = cytotoxic T-lymphocyte-associated protein 4 (show CTLA4 Antibodies)]

  7. PD-1 plays a vital role in brain inflammation via regulation of Fgl-2 (show FGL2 Antibodies) after ICH (show ACE Antibodies), and that manipulation of PD-1 might be a promising therapeutical target in ICH (show ACE Antibodies).

  8. We identified PD-1 to be specifically expressed in PLZF (show ZBTB16 Antibodies)(+) ILCp and revealed that the timing and order of expression of the transcription factors NFIL3 (show NFIL3 Antibodies), ID2, and TCF-1 (show HNF1A Antibodies) was critical. Importantly, induction of ILC (show CCL27 Antibodies) lineage commitment required only transient expression of NFIL3 (show NFIL3 Antibodies) prior to ID2 and TCF-1 (show HNF1A Antibodies) expression.

  9. The identification of the role for PD-1 in regulating B cell-dependent antitumor immunity to Tn antigen highlights an opportunity to develop new therapeutic strategies targeting tumor-associated carbohydrate antigens

  10. These findings suggest that PD-1 pathway blockade may reverse adaptive immune resistance following cyclic dinucleotide treatment, enhancing both local and systemic antitumor immunity.

Rhesus Monkey Programmed Cell Death 1 (PDCD1) interaction partners

  1. Data show that CTLA-4 (show CTLA4 Antibodies)(+)PD-1(-) memory CD4 (show CD4 Antibodies)(+) T cells, which share phenotypic markers with regulatory T cells, were enriched in SIV DNA in blood, lymph nodes (LN), spleen, and gut (show GUSB Antibodies), and contained replication-competent and infectious virus.

  2. Compared to before immunosuppression, PD-1 expression increased at reactivation. Increased T cells before zoster is likely due to virus reactivation.

  3. A PD-1(high) phenotype is associated with accelerated in vivo CD8 (show CD8A Antibodies) T cell turnover in SIV-infections, especially within the SIV-specific CD8 (show CD8A Antibodies) T cell pool.

  4. High levels of PD-1 expression on CD4 (show CD4 Antibodies)(+) T cells in lymph nodes of rhesus macaques can serve as a valuable marker to identify T follicular helper cells.

  5. Data indicate that PD-1 expression is increased as a result of T cell activation during a primary immune response as well as during persistent immune activation in macaques.

  6. PD-1 can serve as a sensitive indicator of persistent, low-level virus replication

PD-1 (PDCD1) Antigen Profile

Protein Summary

This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Gene names and symbols associated with PDCD1

  • programmed cell death 1 (PDCD1) antibody
  • programmed cell death 1 (Pdcd1) antibody
  • CD279 antibody
  • hPD-1 antibody
  • hPD-l antibody
  • Ly101 antibody
  • PD-1 antibody
  • PD1 antibody
  • Pdc1 antibody
  • SLEB2 antibody

Protein level used designations for PDCD1

programmed cell death protein 1 , protein PD-1 , programmed cell death 1 , programmed death 1 , mPD-1

GENE ID SPECIES
5133 Homo sapiens
301626 Rattus norvegicus
424913 Gallus gallus
613842 Bos taurus
18566 Mus musculus
486213 Canis lupus familiaris
100135775 Macaca mulatta
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