anti-Rac GTPase Activating Protein 1 (RACGAP1) Antibodies

The protein encoded by RACGAP1 belongs to the GTPase-activating protein (GAP) family. Additionally we are shipping RACGAP1 Kits (22) and RACGAP1 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RACGAP1 29127 Q9H0H5
RACGAP1 26934 Q9WVM1
RACGAP1 315298  
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Top anti-RACGAP1 Antibodies at

Showing 10 out of 126 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-RACGAP1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>ACHN cell lysate WB Suggested Anti-RACGAP1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: ACHN cell lysate <br /> RACGAP1 is supported by BioGPS gene expression data to be expressed in ACHN 100 μL Log in to see 2 to 3 Days
Cow Rabbit Un-conjugated WB Host: Rabbit <br /> Target Name: Racgap1 <br /> Sample Tissue: Rat Stomach lysates <br /> Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
Human Goat Un-conjugated IHC, ELISA, WB ABIN184690 staining (0.2µg/ml) of Human Testis lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. ABIN184690 (1µg/ml) staining of paraffin embedded Human Testis. Microwaved antigen retrieval with Tris/EDTA buffer pH9, HRP-staining. 100 μg Log in to see 6 to 7 Days
Human Rabbit Un-conjugated EIA, FACS, IF, IHC (p), WB Flow Cytometric analysis of MCF-7 cells using RACGAP1 Antibody (N-term) Cat.-No AP53556PU-N (right histogram) compared to a Negative Control cell (left histogram). FITC-conjugated Goat-anti-Rabbit secondary antibodies were used for the analysis. Confocal immunofluorescent analysis of RACGAP1 Antibody (N-term) Cat.-No AP53556PU-N with MCF-7 cell followed by Alexa Fluor 488-conjugated Goat anti-Rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). 0.4 mL Log in to see 6 to 8 Days
Human Rabbit Un-conjugated IC, IF, IHC, WB Immunofluorescent analysis of MGCRACGAP staining in K562 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of MGCRACGAP staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Log in to see 13 to 14 Days
Human Mouse Un-conjugated WB RACGAP1 monoclonal antibody (M01), clone 1G6. Western Blot analysis of RACGAP1 expression in Jurkat. 0.1 mg Log in to see 8 to 11 Days
Human Rabbit Un-conjugated ICC, IF, IHC (p), IHC, WB Immunohistochemistry-Paraffin: MgcRacGAP/RACGAP1 Antibody [NBP1-33455] - Paraffin-embedded H1299 xenograft. Immunohistochemistry-Paraffin: MgcRacGAP/RACGAP1 Antibody [NBP1-33455] - Paraffin-embedded Hepatoma. 100 μL Log in to see 7 to 9 Days
Human Rabbit Un-conjugated IF, IHC, WB 100 μL Log in to see 16 Days
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Confocal immunofluorescent analysis of RACGAP1 Antibody (N-term)(ABIN655408) with MCF-7 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). 400 μL Log in to see 10 to 11 Days
Human Mouse Un-conjugated ELISA, WB Immunoperoxidase of monoclonal antibody to RACGAP1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 1 ug/ml] Detection limit for recombinant GST tagged RACGAP1 is approximately 0.3ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days

RACGAP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-RACGAP1 Antibodies

  1. Human Monoclonal RACGAP1 Primary Antibody for ELISA, WB - ABIN565414 : Wolfe, Takaki, Petronczki, Glotzer: Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation. in PLoS biology 2009 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal RACGAP1 Primary Antibody for IHC (p), IHC - ABIN257840 : Reibel, Dorseuil, Stancou, Bertoglio, Gacon: A hemopoietic specific gene encoding a small GTP binding protein is overexpressed during T cell activation. in Biochemical and biophysical research communications 1991 (PubMed)

More Antibodies against RACGAP1 Interaction Partners

Xenopus laevis Rac GTPase Activating Protein 1 (RACGAP1) interaction partners

  1. MgcRacGAP SxIP motif is functionally important both for its role in regulating adherens junction structure during interphase and for regulating Rho GTPase activity during cytokinesis.

Human Rac GTPase Activating Protein 1 (RACGAP1) interaction partners

  1. Study showed that a subset of epithelial ovarian cancer (EOC) patients have RacGAP1 overexpression which is associated with advanced tumor stages and poor clinical outcomes. Also, RacGAP1 can positively regulate the activation of RhoA (show RHOA Antibodies) and Erk (show EPHB2 Antibodies) proteins, thus up-enhance the migration and invasion process of EOC.

  2. Data show that comparing with Ki-67 (show MKI67 Antibodies) and TOP2A (show TOP2A Antibodies), RacGAP1 allowed for a clearer prognostic statement.

  3. RACGAP1 promotes the metastatic phenotype in uterine carcinosarcoma via a STAT3 (show STAT3 Antibodies)/survivin (show BIRC5 Antibodies) signaling pathway.

  4. High RACGAP1 expression is associated with Basal-like Breast Cancers.

  5. Data suggest that MGCRABGAP (show TBC1D21 Antibodies) is involved in mammalian spermiogenesis by modulating RAB10 (show RAB10 Antibodies).

  6. This study showed that the overexpressions of Ki67 (show MKI67 Antibodies), RacGAP1, and TOP2a (show TOP2A Antibodies) affect the prognosis of female breast cancer patients adversely

  7. Data confirmed a strong correlation of AURKA (show AURKA Antibodies) and Wnt (show WNT2 Antibodies)-modulator RACGAP1 gene expression both in the gastric tumor, the tumor-adjacent and the tumor-distant mucosa.

  8. RacGAP1 Is a Novel Downstream Effector of E2F7 (show E2F7 Antibodies)-Dependent Resistance to Doxorubicin and Is Prognostic for Overall Survival in Squamous Cell Carcinoma

  9. RACGAP1 expression levels in the nucleus and cytoplasm, determined by immunohistochemical staining, predict opposite clinical outcomes and that both could be independent prognostic markers for colorectal cancer.

  10. central spindle assembly and 2 Plk1 (show PLK1 Antibodies)-dependent phosphorylations are required to establish efficient binding of the Ect2 (show ECT2 Antibodies) BRCT in early cytokinesis.

Mouse (Murine) Rac GTPase Activating Protein 1 (RACGAP1) interaction partners

  1. Deletion of MgcRacGAP in the male germ cells impairs spermatogenesis and causes male sterility in the mouse.

  2. APC (show APC Antibodies)(CDH1 (show CDH1 Antibodies)) targets MgcRacGAP for destruction in the late M phase.

  3. TLR4 (show TLR4 Antibodies) signaling shapes B cell dynamics via MyD88 (show MYD88 Antibodies)-dependent pathways and Rac (show AKT1 Antibodies) GTPases.

  4. several Rho family small GTPases activate PI3K by an indirect cooperative positive feedback that required a combination of Rac (show AKT1 Antibodies), CDC42 (show CDC42 Antibodies), and RhoG small GTPase activities

  5. Rac regulates vascular endothelial growth factor stimulated motility

  6. These results indicate that MgcRacGAP regulates cytokinesis and cellular differentiation as a regulator of Rho family of GTPase and suggest that this process is controlled by some serine/threonine kinases.

  7. alpha5 is required for proliferation and polarity of basal epithelial cells; the interaction between laminin-10/11-integrin alpha6beta4 and the PI3-kinase (show PIK3CA Antibodies)-Cdc42 (show CDC42 Antibodies)/Rac (show AKT1 Antibodies) pathways may play a role in determining the size and shape of tooth germ

  8. Gab2 (show GAB2 Antibodies) via Shp-2 (show PTPN11 Antibodies) is critical for transmitting signals from Kit Tyr (show TYR Antibodies)(567) to activate the Rac (show AKT1 Antibodies)/JNK (show MAPK8 Antibodies) pathway controlling mast cell proliferation

  9. Data demonstrate that normal cytokinesis in B lymphocytes requires the GAP and NH2 terminal domains but not GAP activity of mgcRacGAP.

  10. Rac (show AKT1 Antibodies) became activated within 2 min after peripheral membrane extensions adhered to new ECM (show MMRN1 Antibodies) islands, and this activation wave propagated outward in an oriented manner as the cells spread from island to island

Zebrafish Rac GTPase Activating Protein 1 (RACGAP1) interaction partners

  1. In vivo cell recordings reveal that gradual loss of wild-type RacGAP1 leads progressively from a failure of abscission, then to cleavage furrow ingression, and finally complete absence of furrow formation. Despite the lack of cytokinesis, gross patterning occurs overtly normally in ogre mutants and cells continue to cycle slowly, some even attaining four or eight nuclei.

RACGAP1 Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the GTPase-activating protein (GAP) family. GAPs bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, GAPs negatively regulate Rho-mediated signals. This protein plays a regulatory role in initiation of cytokinesis, controlling cell growth and differentiation of hematopoietic cells, regulating spermatogenesis, and in neuronal proliferation. Alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with RACGAP1

  • Rac GTPase activating protein 1 (racgap1) antibody
  • Rac GTPase activating protein 1 L homeolog (racgap1.2.L) antibody
  • Rac GTPase activating protein 1 (RACGAP1) antibody
  • Rac GTPase activating protein 1 (racgap1.2) antibody
  • Rac GTPase activating protein 1 L homeolog (racgap1.L) antibody
  • rac GTPase-activating protein 1 (RACGAP1) antibody
  • Rac GTPase activating protein 1 (Racgap1) antibody
  • Rac GTPase-activating protein 1 (Racgap1) antibody
  • AI227039 antibody
  • AI327394 antibody
  • Band25 antibody
  • cyk-4 antibody
  • CYK4 antibody
  • gtl11 antibody
  • GTPase antibody
  • HsCYK-4 antibody
  • ID-GAP antibody
  • MGC121578 antibody
  • MgcRacGAP antibody
  • mKIAA1478 antibody
  • RACGAP1 antibody
  • wu:fb92c08 antibody
  • zgc:77839 antibody

Protein level used designations for RACGAP1

Rac GTPase activating protein 1 , rac GTPase-activating protein 1-like , GTPase activating protein , male germ cell RacGap , protein CYK4 homolg , protein CYK4 homolog , rac GTPase-activating protein 1 , Rac GTPase-activating protein 1

407917 Xenopus (Silurana) tropicalis
445828 Xenopus laevis
451887 Pan troglodytes
733574 Xenopus (Silurana) tropicalis
100059818 Equus caballus
100453002 Pongo abelii
100473385 Ailuropoda melanoleuca
100542045 Meleagris gallopavo
100558921 Anolis carolinensis
100595184 Nomascus leucogenys
29127 Homo sapiens
431862 Xenopus laevis
486549 Canis lupus familiaris
514618 Bos taurus
100517651 Sus scrofa
426884 Gallus gallus
100354099 Oryctolagus cuniculus
100721177 Cavia porcellus
26934 Mus musculus
315298 Rattus norvegicus
323197 Danio rerio
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