Sarcosine Dehydrogenase Proteins (SARDH)

SARDH encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. Additionally we are shipping Sarcosine Dehydrogenase Antibodies (13) and Sarcosine Dehydrogenase Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SARDH 1757 Q9UL12
SARDH 192166 Q99LB7
Rat SARDH SARDH 114123 Q64380
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Top Sarcosine Dehydrogenase Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Delivery Price Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
$13,741.67
Details
Escherichia coli (E. coli) Human Un-conjugated   50 μg 71 Days
$867.02
Details
Yeast Human Un-conjugated   50 μg 71 Days
$1,094.44
Details
Mammalian Cells Human Un-conjugated   100 μg 71 Days
$2,757.42
Details

SARDH Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,

Mouse (Murine)

More Proteins for Sarcosine Dehydrogenase (SARDH) Interaction Partners

Human Sarcosine Dehydrogenase (SARDH) interaction partners

  1. Data first reported a deleterious c.551C>T mutation in SARDH in sporadic colorectal cancer (sCRC). SARDH was identified as a novel tumor suppressor gene and was abnormally decreased in sCRC at both the transcriptional and the translational level. SARDH overexpression inhibited the proliferation, migration, and invasion of CRC cell lines, whereas its depletion improved these processes.

  2. The SNPs rs2797840 and rs2073817 in SARDH may serve as an indicator for the occurrence of neural tube defects in the Chinese Han population, and rs2797840 may also be an indicator for folate content of brain.

  3. Expression of sarcosine metabolism-related proteins differed between ILC [invasive lobular carcinoma] and IDC [invasive ductal carcinoma].

  4. SARDH and TMEFF2 cooperate to modulate one-carbon metabolism and invasion of prostate cancer cells.

  5. Mutations in the SARDH gene are associated with sarcosinemia.

Sarcosine Dehydrogenase (SARDH) Protein Profile

Protein Summary

This gene encodes an enzyme localized to the mitochondrial matrix which catalyzes the oxidative demethylation of sarcosine. This enzyme is distinct from another mitochondrial matrix enzyme, dimethylglycine dehydrogenase, which catalyzes a reaction resulting in the formation of sarcosine. Mutations in this gene are associated with sarcosinemia. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with SARDH

  • sarcosine dehydrogenase (SARDH)
  • sarcosine dehydrogenase (SAV_6951)
  • sarcosine dehydrogenase, mitochondrial (LOC5565677)
  • sarcosine dehydrogenase, mitochondrial (LOC5572760)
  • sarcosine dehydrogenase (SDH)
  • sarcosine dehydrogenase (NGR_b16520)
  • Sarcosine dehydrogenase (Sinme_2254)
  • sarcosine dehydrogenase (sardh)
  • sarcosine dehydrogenase (Sardh)
  • BPR-2 protein
  • DMGDHL1 protein
  • SAR protein
  • SARD protein
  • SDH protein
  • zgc:56363 protein

Protein level used designations for SARDH

dimethylglycine dehydrogenase-like 1 , sarcosine dehydrogenase, mitochondrial , sarcosine dehydrogenase , Sarcosine dehydrogenase

GENE ID SPECIES
1757 Homo sapiens
1217178 Streptomyces avermitilis MA-4680
5565677 Aedes aegypti
5572760 Aedes aegypti
7444857 Thalassiosira pseudonana CCMP1335
7788975 Sinorhizobium fredii NGR234
10726848 Sinorhizobium meliloti AK83
10952277 Roseobacter litoralis Och 149
192166 Mus musculus
114123 Rattus norvegicus
394103 Danio rerio
491277 Canis lupus familiaris
614603 Bos taurus
100718504 Cavia porcellus
100154338 Sus scrofa
417146 Gallus gallus
100069193 Equus caballus
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