×
For best experience we recommend to activate Javascript in your browser.
MEFV antibody (AA 2-29)
MEFV
Reactivity: Human
WB, IP
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MEFV Antibody
(hide)
Target
See all MEFV Antibodies
MEFV
(Mediterranean Fever (MEFV))
Binding Specificity
All epitopes for MEFV antibodies
AA 2-29
Reactivity
All reactivities for MEFV antibodies
Human
Host
All hosts for MEFV antibodies
Rabbit
Clonality
All clonalities for MEFV antibodies
Polyclonal
Conjugate
All conjugates for MEFV antibodies
This MEFV antibody is un-conjugated
Application
All applications for MEFV antibodies
Western Blotting (WB), Immunoprecipitation (IP)
Specificity
Recognizes human pyrin.
Cross-Reactivity
Human
Immunogen
Synthetic peptide corresponding to aa 2-29 (A2KTPSDHLLSTLEELVPYDFEKFKFKLQ29) of human pyrin.
Top Product
Discover our top product MEFV Primary Antibody
Alternatives
(show)
Application Details
(hide)
Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
(hide)
Format
Liquid
Concentration
Lot specific
Buffer
In PBS containing 10 % glycerol and 0.02 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 1 year after receipt when stored at -20°C.
Expiry Date
12 months
References for anti-MEFV antibody (ABIN1169260)
(hide)
Papin, Cuenin, Agostini, Martinon, Werner, Beer, Grütter, Grütter, Tschopp : "The SPRY domain of Pyrin, mutated in familial Mediterranean fever patients, interacts with inflammasome components and inhibits proIL-1beta processing. " in: Cell death and differentiation , Vol. 14 , Issue 8 , pp. 1457-66 , (2007 ) (PubMed ).
Target Details for MEFV
(hide)
Target
MEFV
(Mediterranean Fever (MEFV))
Alternative Name
Pyrin (MEFV Products )
Synonyms
pyrin antibody, MEFV antibody, FMF antibody, MEF antibody, TRIM20 antibody, rfp domain antibody, MEFV, pyrin innate immunity regulator antibody, Mediterranean fever antibody, MEFV antibody, Mefv antibody
Background
Pyrin regulates inflammation by interacting with the cytoskeleton. Pyrin may direct the migration of white blood cells to sites of inflammation and stop or slow the inflammatory response when it is no longer needed. Defects in pyrin are the cause for Mediterranean fever.
UniProt
O15553
Pathways
Positive Regulation of Endopeptidase Activity
Recently viewed
(hide)