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CD11b antibody (APC)

ITGAM Reactivity: Rat FACS Host: Mouse Monoclonal OX-42 APC

Catalog No. ABIN133345

Datasheet as PDF

Target See all CD11b (ITGAM) Antibodies

CD11b (ITGAM) (Integrin alpha M (ITGAM))
Reactivity
249

156

60

33

17

17

16

14

11

7

7

5

4

2

2

1
Rat
Host
131

99

95

3

1

1
Mouse
Compatible Secondaries
Clonality
233

93

1
Monoclonal
Conjugate
108

37

29

25

18

10

7

6

6

6

5

5

4

4

4

4

4

4

3

3

3

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This CD11b antibody is conjugated to APC
Application
247

78

74

69

55

36

36

23

20

18

13

13

7

6

5

5

4

3

2

2

2

1

1
Flow Cytometry (FACS)

Specificity

Rat CD11b/c

Immunogen

Rat Peritoneal Macrophages . Fusion Partner: NSO/U mouse myeloma cell line . Donor: BALB/c spleen

Clone

OX-42

Isotype

IgG2a

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ITGAM Reactivity: Human, Mouse, Rat FACS Host: Rabbit Polyclonal unconjugated

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ITGAM Reactivity: Human FACS, WB, IHC (p) Host: Rabbit Polyclonal RB17991 unconjugated

anti-Integrin alpha M (ITGAM) (AA 145-340) antibody
ITGAM Reactivity: Human IHC, WB, IF Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 77-180) antibody
ITGAM Reactivity: Human, Mouse, Rat FACS, WB, IHC (fro), ELISA, IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) (AA 31-160) antibody
ITGAM Reactivity: Rat IHC, WB, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-Integrin alpha M (ITGAM) antibody (Biotin)
ITGAM Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-174 Biotin

anti-Integrin alpha M (ITGAM) antibody (FITC)
ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 FITC

anti-Integrin alpha M (ITGAM) antibody (PE)
ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 PE

anti-Integrin alpha M (ITGAM) (AA 623-728) antibody
ITGAM Reactivity: Human WB, ELISA, ICC Host: Mouse Monoclonal 3A10H5 unconjugated

anti-Integrin alpha M (ITGAM) (AA 941-1074) antibody
ITGAM Reactivity: Human IHC, WB, StM Host: Mouse Monoclonal ITGAM-3338 unconjugated

Restrictions

For Research Use only
Concentration

0.2 mg/ml

Storage

4 °C
Target

CD11b (ITGAM) (Integrin alpha M (ITGAM))

Alternative Name

CD11b/c (ITGAM Products)

Synonyms

CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody

Background

Anti-rat CD11b/c monoclonal antibody recognizes most macrophages including resident peritoneal macrophages, kupffer cells, but only approximately 35% of alveolar macrophages (2). ABIN133345also labels dendritic cells extensively, granulocytes and cells with morphology of microglia in the brain. It precipitates three polypeptides of M.W. 160, 103 and 95kDa. ABIN133345inhibits complement mediated rosettes and is probably the rat equivalent of the human receptor for iC3b called CR3. anti-rat CD11b/c mAb should prove useful in the recognition of macrophages and microglia.

Pathways

Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation