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Caspase 9 antibody (AA 299-318)
CASP9
Reactivity: Human
WB, IF, ICC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Caspase 9 Antibody
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Target
See all Caspase 9 (CASP9) Antibodies
Caspase 9 (CASP9)
(Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
Binding Specificity
All epitopes for Caspase 9 antibodies
AA 299-318
Reactivity
All reactivities for Caspase 9 antibodies
Human
Host
All hosts for Caspase 9 antibodies
Rabbit
Clonality
All clonalities for Caspase 9 antibodies
Polyclonal
Conjugate
All conjugates for Caspase 9 antibodies
This Caspase 9 antibody is un-conjugated
Application
All applications for Caspase 9 antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
Specificity
Reacts with full lengh human Caspase-9.
Purification
Purified
Immunogen
Peptide corresponding to aa 299- 318 of human caspase-9
Isotype
IgG
Top Product
Discover our top product CASP9 Primary Antibody
Alternatives
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anti-Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9) (AA 11-120) antibody
CASP9
Reactivity: Human, Mouse, Rat, Chicken, Dog, Rabbit
WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Host: Rabbit
Polyclonal
unconjugated
Application Details
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Application Notes
Working dilution: Optimal dilution should be determined by the end user. The following are guidelines only: ICC(2 μg/mL) WB(1 μg/mL)
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS, pH 7.4
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Dilute in PBS or medium which is identical to that used in the assay system.
Storage
-20 °C
Storage Comment
Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
Expiry Date
12 months
Target Details for Caspase 9
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Target
Caspase 9 (CASP9)
(Caspase 9, Apoptosis-Related Cysteine Peptidase (CASP9))
Alternative Name
Caspase-9 (CASP9 Products )
Synonyms
CASP9 antibody, AI115399 antibody, APAF-3 antibody, AW493809 antibody, CASP-9 antibody, Caspase-9 antibody, ICE-LAP6 antibody, Mch6 antibody, Apaf3 antibody, Casp-9-CTD antibody, Casp9_v1 antibody, Ice-Lap6 antibody, APAF3 antibody, MCH6 antibody, PPP1R56 antibody, caspase 9 antibody, CASP9 antibody, Casp9 antibody
Background
Cell death signals are transduced by death domain-containing adapter molecules and members of the caspase family of proteases. Caspase-9 and Apaf-1 bind to each other, which leads to caspase-9 activation. Caspase-9 is also activated by granzyme B and CPP32. Activated caspase-9 cleaves and activates caspase-3, a protease responsible for proteolytic cleavage of many key proteins involved in apoptosis. Caspase-9 plays a central role in cell death induced by a wide variety of apoptosis inducers including TNFa , TRAIL, anti-CD95, FADD, and TRADD. Caspase-9 is expressed in a variety of human tissues. Caspase-9, CASP-9 Apoptotic protease Mch-6 Apoptotic protease-activating factor 3, APAF-3 ICE-like apoptotic protease 6, ICE-LAP6 Gene name: CASP9, MCH6
Gene ID
842
UniProt
P55211
Pathways
MAPK Signaling , RTK Signaling , Apoptosis , Caspase Cascade in Apoptosis , Fc-epsilon Receptor Signaling Pathway , EGFR Signaling Pathway , Neurotrophin Signaling Pathway , Positive Regulation of Endopeptidase Activity
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