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TNF alpha antibody
TNF alpha
Reactivity: Human, Mouse, Rat
IHC, IF/ICC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TNF alpha Antibody
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Target
See all TNF alpha Antibodies
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Reactivity
All reactivities for TNF alpha antibodies
Human, Mouse, Rat
Host
All hosts for TNF alpha antibodies
Rabbit
Clonality
All clonalities for TNF alpha antibodies
Polyclonal
Conjugate
All conjugates for TNF alpha antibodies
This TNF alpha antibody is un-conjugated
Application
All applications for TNF alpha antibodies
Immunohistochemistry (IHC), Immunofluorescence (fixed cells) (IF/ICC)
Specificity
TNFA Antibody detects endogenous levels of total TNFA.
Purification
Immunogen affinity purified
Immunogen
A synthesized peptide derived from human TNFA.
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Rabbit IgG in PBS, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Expiry Date
12 months
Target Details for TNF alpha
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Target
TNF alpha
(Tumor Necrosis Factor alpha (TNF alpha))
Alternative Name
TNFA (TNF alpha Products )
Synonyms
DIF antibody, TNF-alpha antibody, TNFA antibody, TNFSF2 antibody, RATTNF antibody, Tnfa antibody, tnf antibody, TNF-a antibody, TNFalpha antibody, Tnfsf1a antibody, TNFa antibody, cTNF antibody, Tnf-alpha antibody, tnfa-like antibody, TNF-ALPHA antibody, dif antibody, tnfa antibody, xtnf antibody, tnfsf2 antibody, tnf-alpha antibody, Cachectin antibody, tumor necrosis factor antibody, tumor necrosis factor b (TNF superfamily, member 2) antibody, tumor necrosis factor alpha antibody, tumor necrosis factor a (TNF superfamily, member 2) antibody, TNF antibody, Tnf antibody, tnf antibody, tnfb antibody, tnf-alpha antibody, LOC103694380 antibody, tnfa antibody
Background
This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation.
Gene ID
7124
UniProt
P01375
Pathways
NF-kappaB Signaling , Apoptosis , Caspase Cascade in Apoptosis , TLR Signaling , Cellular Response to Molecule of Bacterial Origin , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Production of Molecular Mediator of Immune Response , Positive Regulation of Endopeptidase Activity , Hepatitis C , Protein targeting to Nucleus , Inflammasome
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