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AGT antibody (AA 28-248)
AGT
Reactivity: Human
WB, IHC
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-AGT Antibody
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Target
See all AGT Antibodies
AGT
(Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
Binding Specificity
All epitopes for AGT antibodies
AA 28-248
Reactivity
All reactivities for AGT antibodies
Human
Host
All hosts for AGT antibodies
Rabbit
Clonality
All clonalities for AGT antibodies
Polyclonal
Conjugate
All conjugates for AGT antibodies
This AGT antibody is un-conjugated
Application
All applications for AGT antibodies
Western Blotting (WB), Immunohistochemistry (IHC)
Purification
Purified by antigen-affinity chromatography.
Immunogen
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 28 and 248 of Human AGT
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Application Details
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Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.50-1.500
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for AGT
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Target
AGT
(Angiotensinogen (serpin Peptidase Inhibitor, Clade A, Member 8) (AGT))
Abstract
AGT Products
Synonyms
ANHU antibody, SERPINA8 antibody, AI265500 antibody, AngI antibody, AngII antibody, Aogen antibody, Serpina8 antibody, ANRT antibody, Ang antibody, PAT antibody, wu:fb62f06 antibody, wu:fj87b02 antibody, zgc:111892 antibody, AGT antibody, angt antibody, ANGT antibody, angiotensinogen antibody, angiotensinogen (serpin peptidase inhibitor, clade A, member 8) antibody, AGT antibody, Agt antibody, agt antibody
Background
The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure.The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II.The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia.Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development.Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.[provided by RefSeq]
Molecular Weight
53 kDa
Gene ID
183
NCBI Accession
NM_000029 , NP_000020
Pathways
JAK-STAT Signaling , ACE Inhibitor Pathway , EGFR Signaling Pathway , Peptide Hormone Metabolism , Regulation of Systemic Arterial Blood Pressure by Hormones , Regulation of Lipid Metabolism by PPARalpha , Protein targeting to Nucleus , Feeding Behaviour , Monocarboxylic Acid Catabolic Process , Dicarboxylic Acid Transport , Positive Regulation of Response to DNA Damage Stimulus , Regulation of long-term Neuronal Synaptic Plasticity
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