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XRCC5 antibody (AA 315-563)
XRCC5
Reactivity: Human
WB, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-XRCC5 Antibody
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Target
See all XRCC5 Antibodies
XRCC5
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))
Binding Specificity
All epitopes for XRCC5 antibodies
AA 315-563
Reactivity
All reactivities for XRCC5 antibodies
Human
Host
All hosts for XRCC5 antibodies
Rabbit
Clonality
All clonalities for XRCC5 antibodies
Polyclonal
Conjugate
All conjugates for XRCC5 antibodies
This XRCC5 antibody is un-conjugated
Application
All applications for XRCC5 antibodies
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Purification
Purified by antigen-affinity chromatography.
Immunogen
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 315 and 563 of Ku80 (XRCC5)
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Discover our top product XRCC5 Primary Antibody
Alternatives
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Application Details
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Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000 Immunohistochemistry: 1.100-1.250 Immunofluorescence: 1.100-1.200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for XRCC5
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Target
XRCC5
(X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5 (Double-Strand-Break Rejoining) (XRCC5))
Alternative Name
Ku80(XRCC5) (XRCC5 Products )
Synonyms
AI314015 antibody, Ku80 antibody, Ku86 antibody, Kup80 antibody, KARP-1 antibody, KARP1 antibody, KU80 antibody, KUB2 antibody, NFIV antibody, xrcc5-a antibody, XRCC5 antibody, X-ray repair cross complementing 5 antibody, X-ray repair complementing defective repair in Chinese hamster cells 5 antibody, X-ray repair complementing defective repair in Chinese hamster cells 5 L homeolog antibody, XRCC5 antibody, Xrcc5 antibody, xrcc5.L antibody
Background
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5.Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events.This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination.A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.[provided by RefSeq]
Molecular Weight
83 kDa
Gene ID
7520
NCBI Accession
NP_066964 , NM_021141
Pathways
DNA Damage Repair
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