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GAD65 antibody (AA 465-528)
GAD2
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-GAD65 Antibody
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Target
See all GAD65 (GAD2) Antibodies
GAD65 (GAD2)
(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
Binding Specificity
All epitopes for GAD65 antibodies
AA 465-528
Reactivity
All reactivities for GAD65 antibodies
Human
Host
All hosts for GAD65 antibodies
Rabbit
Clonality
All clonalities for GAD65 antibodies
Polyclonal
Conjugate
All conjugates for GAD65 antibodies
This GAD65 antibody is un-conjugated
Application
All applications for GAD65 antibodies
Western Blotting (WB)
Purification
Purified by antigen-affinity chromatography.
Immunogen
Synthetic peptide contain a sequence corresponding to a region within amino acids 465 and 528 of Human GAD2
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Alternatives
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Application Details
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Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for GAD65
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Target
GAD65 (GAD2)
(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
Alternative Name
GAD65 (GAD2 Products )
Synonyms
GAD65 antibody, gad65 antibody, F12P19.12 antibody, F12P19_12 antibody, GLUTAMATE DECARBOXYLASE 2 antibody, glutamate decarboxylase 2 antibody, zgc:112198 antibody, 6330404F12Rik antibody, GAD(65) antibody, Gad-2 antibody, glutamate decarboxylase 2 antibody, glutamate decarboxylase 1 antibody, glutamic acid decarboxylase 2 antibody, GAD2 antibody, PTRG_06148 antibody, LOC9324534 antibody, Gad2 antibody, GAD1 antibody, gad2 antibody
Background
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes.The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid.A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes.This gene may also play a role in the stiff man syndrome.Alternative splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq]
Molecular Weight
65 kDa
Gene ID
2572
NCBI Accession
NP_000809 , NM_000818
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