Kallikrein 6 antibody (AA 145-156)

Catalog No. ABIN1908534

Product Details anti-Kallikrein 6 Antibody

Target: Kallikrein 6 (KLK6)

Binding Specificity: AA 145-156

Reactivity: Human, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This Kallikrein 6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Brand: IHC-plus™

Specificity: Human KLK6 / Kallikrein 6. This antibody is expected to recognize both reported isoforms (NP_002765.1, NP_001012983.1). Reported variants represent identical protein: NP_002765.1, NP_001012982.1.

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-KTADGDFPDTIQ from an internal region of human KLK6 / Kallikrein 6 (NP_002765.1, NP_001012983.1). Percent identity by BLAST analysis: Human, Gorilla, Monkey (100%), Elephant (92%), Ferret, Panda, Horse (83%), Mouse (75%), Rat (67%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), Peptide-ELISA (1:128000)

Usage: Peptide ELISA: antibody detection limit dilution 1:128000. Western blot: Preliminary experiments gave an approx 50kD band in Human Ovary lysates after 0.5 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 26.9kD according to NP_002765.1. The 50kD band was successfully blocked by incubation with the immunizing peptide.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Kallikrein 6

Target: Kallikrein 6 (KLK6)

Alternative Name: KLK6 / Kallikrein 6 (KLK6 Products)

Synonyms: Bssp antibody, Klk7 antibody, PRSS18 antibody, PRSS9 antibody, SP59 antibody, hK6 antibody, Prss9 antibody, AI849898 antibody, BSP antibody, Klk29 antibody, MSP antibody, Prss18 antibody, neurosin antibody, kallikrein related peptidase 6 antibody, kallikrein related-peptidase 6 antibody, kallikrein-6 antibody, KLK6 antibody, Klk6 antibody, LOC100716801 antibody

Background: Name/Gene ID: KLK6
Subfamily: Serine S1
Family: Protease

Synonyms: KLK6, Bssp, HK6, Kallikrein-related peptidase 6, Kallikrein 6 (neurosin, zyme), Neurosin, Protease, serine, 18, Protease M, PRSS9, Serine protease 9, Zyme, Serine protease 18, Kallikrein 6, Kallikrein-6, PRSS18, SP59

Gene ID: 5653

NCBI Accession: NP_002765, NP_001012983

Pathways: Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling