SHP1 antibody (AA 501-595)
-
- Target See all SHP1 (PTPN6) Antibodies
- SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
-
Binding Specificity
- AA 501-595
-
Reactivity
- Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This SHP1 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA
- Cross-Reactivity
- Rat
- Predicted Reactivity
- Human,Mouse,Dog,Cow,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human PTPN6/SHP1
- Isotype
- IgG
- Top Product
- Discover our top product PTPN6 Primary Antibody
-
-
- Application Notes
-
WB 1:300-5000
ELISA 1:500-1000 - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
-
- Target
- SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))
- Alternative Name
- Shp1 (PTPN6 Products)
- Synonyms
- HCPH antibody, HPTP1C antibody, PTP-1C antibody, SH-PTP1 antibody, SHP-1 antibody, SHP-1L antibody, SHP1 antibody, DRPLA antibody, Hcph antibody, Ptp1C antibody, me antibody, motheaten antibody, Ptph6 antibody, Shp-1 antibody, fj22f05 antibody, wu:fj22f05 antibody, zgc:55501 antibody, ptpn6 antibody, protein tyrosine phosphatase, non-receptor type 6 antibody, protein tyrosine phosphatase, non-receptor type 6 L homeolog antibody, PTPN6 antibody, Ptpn6 antibody, ptpn6 antibody, ptpn6.L antibody
- Background
-
Synonyms: HCP, HCPH, SHP1, SHP-1, HPTP1C, PTP-1C, SHP-1L, SH-PTP1, Tyrosine-protein phosphatase non-receptor type 6, Hematopoietic cell protein-tyrosine phosphatase, Protein-tyrosine phosphatase 1C, Protein-tyrosine phosphatase SHP-1, PTPN6, PTP1C
Background: Modulates signaling by tyrosine phosphorylated cell surface receptors such as KIT and the EGF receptor/EGFR. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation. Plays a key role in hematopoiesis.
- Gene ID
- 5777
- UniProt
- P29350
- Pathways
- JAK-STAT Signaling, TCR Signaling, TLR Signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling
-