CD46 antibody (PE)

Catalog No. ABIN232459

Product Details anti-CD46 Antibody (PE)

Target: CD46

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD46 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Specificity: Recognizes the human CD46 cell surface antigen, a broadly expressed glycoprotein also known as membrane co-factor protein (MCP). CD46 functions as an inhibitor of complement activation limiting the formation and activity of C3 convertases. CD46 is expressed by all nucleated cells, often as multiple isoforms on the same cells. The molecule is also expressed by sperm and may be important in the process of fertilization.

Purification: Protein A purified

Immunogen: HPB-ALL cell line.

Type of Immunogen: Cells

Isotype: IgG

Application Details

Application Notes: Approved: Flo

Usage: Flow Cytometry: Neat. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Reconstitute in 1 mL of Sterile 40-50 % glycerol, distilled water.

Concentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.2, 0.1 % sodium azide, 1 % BSA.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for CD46

Target: CD46

Alternative Name: MCP / CD46 (CD46 Products)

Synonyms: AHUS2 antibody, MCP antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Mcp antibody, CD46 antibody, CD46 molecule antibody, CD46 antigen, complement regulatory protein antibody, CD46 molecule, complement regulatory protein antibody, membrane cofactor protein-like antibody, CD46 antibody, Cd46 antibody, LOC100341359 antibody, LOC103789310 antibody

Background: Name/Gene ID: CD46

Synonyms: CD46, AHUS2, CD46 antigen, MCP, Measles virus receptor, TLX, MIC10, TRA2.10, Membrane cofactor protein

Gene ID: 4179

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization