PARP2 antibody

Catalog No. ABIN2460802

Product Details anti-PARP2 Antibody

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PARP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PARP2.

Application Details

Application Notes: PARP2 antibody can be used for detection of PARP2 by ELISA at 1:62500. PARP2 antibody can be used for detection of PARP2 by western blot at 1.6 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Handling Advice: As with any antibody avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PARP2 antibody at -20 °C.

Target Details for PARP2

Target: PARP2 (Poly (ADP-Ribose) Polymerase 2 (PARP2))

Alternative Name: PARP2 (PARP2 Products)

Synonyms: ADPRT2 antibody, ADPRTL2 antibody, ADPRTL3 antibody, ARTD2 antibody, PARP-2 antibody, pADPRT-2 antibody, Adprt2 antibody, Adprtl2 antibody, Aspartl2 antibody, C78626 antibody, cb996 antibody, adprtl2 antibody, ADPRT-2 antibody, APP antibody, ATPARP1 antibody, PARP1 antibody, POLY(ADP-RIBOSE) POLYMERASE antibody, POLY(ADP-RIBOSE) POLYMERASE 1 antibody, PP antibody, T14P8.19 antibody, T14P8_19 antibody, poly(ADP-ribose) polymerase antibody, poly(ADP-ribose) polymerase 2 antibody, poly(ADP-ribose) polymerase 2 antibody, poly (ADP-ribose) polymerase family, member 2 antibody, poly (ADP-ribose) polymerase 2 antibody, poly(ADP-ribose) polymerase 2 S homeolog antibody, poly(ADP-ribose) polymerase antibody, PARP2 antibody, Parp2 antibody, parp2 antibody, parp2.S antibody

Background: PARP2 contains a catalytic domain and is capable of catalyzing a poly (ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of protein.

Molecular Weight: 61 kDa

Gene ID: 10038

NCBI Accession: NP_005475

UniProt: Q9UGN5

Pathways: DNA Damage Repair