EPH Receptor A7 antibody (pTyr791)

Catalog No. ABIN2568103

Product Details anti-EPH Receptor A7 Antibody

Target: EPH Receptor A7 (EPHA7)

Binding Specificity: pTyr791

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPH Receptor A7 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: The antibody detects endogenous levels of EPHA7only when phosphorylated at tyrosine 791.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: EPHA7 (phospho Tyr791) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 791 (A-V-Y (p)-T-T) derived from Human EPHA7 .

Isotype: IgG

Application Details

Application Notes: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for EPH Receptor A7

Target: EPH Receptor A7 (EPHA7)

Alternative Name: EPHA7 (EPHA7 Products)

Synonyms: fc51g03 antibody, wu:fc51g03 antibody, si:dkey-23k6.1 antibody, EHK3 antibody, HEK11 antibody, Cek11 antibody, Ebk antibody, Ehk3 antibody, Hek11 antibody, Mdk1 antibody, CEPHA7 antibody, EPH receptor A7 antibody, eph receptor A7 antibody, ephrin type-B receptor 1-B antibody, Eph receptor A7 antibody, EPHA7 antibody, epha7 antibody, LOC100166161 antibody, Epha7 antibody

Background: Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Among GPI-anchored ephrin-A ligands, EFNA5 is a cognate/functional ligand for EPHA7 and their interaction regulates brain development modulating cell-cell adhesion and repulsion. Has a repellent activity on axons and is for instance involved in the guidance of corticothalamic axons and in the proper topographic mapping of retinal axons to the colliculus.

Molecular Weight: 112 kDa

Gene ID: 2045

NCBI Accession: NP_004431

UniProt: Q15375

Pathways: RTK Signaling