CBX3 antibody (pSer93)

Catalog No. ABIN2568193

Product Details anti-CBX3 Antibody

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Binding Specificity: pSer93

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CBX3 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: The antibody detects endogenous levels of HP1γ only when phosphorylated at serine 93.

Purification: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: HP1gamma (phospho Ser93) antibody was raised against a peptide sequence around phosphorylation site of Serine 93 (R-L-S (p)-L-S) derived from Human HP1gamma .

Isotype: IgG

Application Details

Application Notes: Western Blot: 1:500~1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store antibody at -20°C for up to one year.

Target Details for CBX3

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Alternative Name: HP1gamma (CBX3 Products)

Synonyms: HECH antibody, HP1-GAMMA antibody, HP1Hs-gamma antibody, Hp1-gamma antibody, HP1g antibody, M32 antibody, cbx3 antibody, cbx3a antibody, xhp1g antibody, wu:fb61b02 antibody, zgc:153397 antibody, chromobox 3 antibody, chromobox 3 L homeolog antibody, chromobox protein homolog 3 pseudogene antibody, chromobox homolog 3a (HP1 gamma homolog, Drosophila) antibody, CBX3 antibody, Cbx3 antibody, cbx3.L antibody, LOC100355282 antibody, cbx3a antibody

Background: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

Molecular Weight: 24 kDa

Gene ID: 11335, 653972

NCBI Accession: NP_009207

UniProt: Q13185