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TNFRSF10B antibody (PE)

TNFRSF10B Reactivity: Mouse FACS, IP Host: Hamster Monoclonal MD5-1 PE
Catalog No. ABIN2663239
  • Target See all TNFRSF10B Antibodies
    TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
    Reactivity
    • 99
    • 18
    • 4
    • 1
    • 1
    Mouse
    Host
    • 64
    • 39
    • 3
    • 1
    • 1
    • 1
    Hamster
    Clonality
    • 61
    • 45
    • 2
    Monoclonal
    Conjugate
    • 73
    • 10
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNFRSF10B antibody is conjugated to PE
    Application
    • 74
    • 35
    • 31
    • 25
    • 17
    • 16
    • 15
    • 13
    • 12
    • 11
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
    Clone
    MD5-1
    Isotype
    IgG
    Top Product
    Discover our top product TNFRSF10B Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.2 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Protect from prolonged exposure to light. Do not freeze.
    Storage
    4 °C
    Storage Comment
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
    Alternative Name
    CD262 (TNFRSF10B Products)
    Synonyms
    TNFRSF10B antibody, dr5 antibody, cd262 antibody, killer antibody, trick2 antibody, trickb antibody, xDR-M1 antibody, xDR-M2 antibody, ztnfr9 antibody, trailr2 antibody, trick2a antibody, trick2b antibody, CD262 antibody, DR5 antibody, KILLER antibody, KILLER/DR5 antibody, TRAIL-R2 antibody, TRAILR2 antibody, TRICK2 antibody, TRICK2A antibody, TRICK2B antibody, TRICKB antibody, ZTNFR9 antibody, Ly98 antibody, MK antibody, tumor necrosis factor receptor superfamily, member 10b antibody, tumor necrosis factor receptor superfamily member 10b S homeolog antibody, tumor necrosis factor receptor superfamily member 10b L homeolog antibody, tumor necrosis factor receptor superfamily member 10b antibody, TNF receptor superfamily member 10b antibody, Tnfrsf10b antibody, TNFRSF10B antibody, tnfrsf10b.S antibody, tnfrsf10b.L antibody, tnfrsf10b antibody
    Background
    CD262 is a 55 kD protein also known as DR5, TRAIL-R2, Apo-2, TRICK2, and KILLER. DR5 is member 10B of the TNF receptor superfamily (TNFRSF10B), widely expressed in normal tissues and some tumor cell lines. The DR5 receptor binds to TRAIL and interacts with the cytoplasmic proteins TRADD and RIP. TRAIL binding to DR5 activates NF- κB and induces apoptosis. DR5 is induced by wild-type p53.
    Pathways
    p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity
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