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PCNA antibody
PCNA
Reactivity: Human, Mouse, Rat
FACS
Host: Mouse
Monoclonal
PC10
unconjugated
Product Details anti-PCNA Antibody
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Target
See all PCNA Antibodies
PCNA
(Proliferating Cell Nuclear Antigen (PCNA))
Reactivity
All reactivities for PCNA antibodies
Human, Mouse, Rat
Host
All hosts for PCNA antibodies
Mouse
Clonality
All clonalities for PCNA antibodies
Monoclonal
Conjugate
All conjugates for PCNA antibodies
This PCNA antibody is un-conjugated
Application
All applications for PCNA antibodies
Flow Cytometry (FACS)
Cross-Reactivity
others
Characteristics
The PC10 monoclonal antibody reacts with proliferating cell nuclear antigen also known as PCNA or the DNA polymerase δ auxiliary protein. PCNA is a 36 kD trimeric ring that acts as a DNA-polymerase sliding clamp expressed in the nucleus of all proliferating cells. A prime function of PCNA appears to be increasing DNA polymerase δ processibility during elongation of the leading strand. PCNA is a useful marker for DNA synthesis and is highly conserved among most species, thus highlighting the very broad reactivity of this antibody.
Purification
The antibody was purified by affinity chromatography.
Clone
PC10
Isotype
IgG2a kappa
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Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Storage Comment
The antibody solution should be stored undiluted between 2°C and 8°C.
Target Details for PCNA
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Target
PCNA
(Proliferating Cell Nuclear Antigen (PCNA))
Alternative Name
PCNA (PCNA Products )
Synonyms
PCNAR antibody, Pcna/cyclin antibody, pcna antibody, AO090003000846 antibody, 53/13 antibody, CG9193 antibody, DmPCNA antibody, Dmel\\CG9193 antibody, MUS209 antibody, Mus209 antibody, PCNA antibody, PCNA/mus209 antibody, Pcna antibody, dPCNA antibody, l(2)02448 antibody, l(2)56F antibody, l(2)56Fa antibody, l(2)s1534 antibody, cb16 antibody, fb36g03 antibody, wu:fa28e03 antibody, wu:fb36g03 antibody, pcna-A antibody, proliferating cell nuclear antigen antibody, DNA polymerase III sliding clamp antibody, Proliferating cell nuclear antigen antibody, Proliferating cell nuclear antigen-like antibody, proliferating cell nuclear antigen L homeolog antibody, proliferating cell nuclear antigen 1 antibody, PCNA antibody, Pcna antibody, pcna antibody, MMP_RS08810 antibody, ANI_1_512014 antibody, AOR_1_1500154 antibody, MGC53867 antibody, pcna.L antibody, pcna1 antibody, LOC106420145 antibody, pcn1 antibody
Pathways
Telomere Maintenance , DNA Damage Repair , Mitotic G1-G1/S Phases , DNA Replication , Synthesis of DNA , Autophagy
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