c-MYC antibody (AA 1-262)

Catalog No. ABIN2668816

There are 2+ publications for this product available. The Rat Monoclonal anti-c-MYC antibody is suitable to detect c-MYC in samples from Human. It has been validated for WB, IP and EMSA.

Quick Overview for c-MYC antibody (AA 1-262) (ABIN2668816)

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This c-MYC antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Electrophoretic Mobility-Shift Assay (EMSA)

Clone: 6A10

Product Details anti-c-MYC Antibody

Binding Specificity: AA 1-262

Purification: Protein G Chromatography

Immunogen: This c-Myc antibody was raised against a recombinant protein corresponding to amino acids 1-262 of human c-Myc protein.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-c-MYC antibody (ABIN2668816)

Vervoorts, Lüscher-Firzlaff, Rottmann, Lilischkis, Walsemann, Dohmann, Austen, Lüscher: "Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP." in: EMBO reports, Vol. 4, Issue 5, pp. 484-90, (2003) (PubMed).

Sommer, Bousset, Kremmer, Austen, Lüscher: "Identification and characterization of specific DNA-binding complexes containing members of the Myc/Max/Mad network of transcriptional regulators." in: The Journal of biological chemistry, Vol. 273, Issue 12, pp. 6632-42, (1998) (PubMed).

Target Details for c-MYC

Target: c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Alternative Name: C-Myc

Molecular Weight: 68 kDa

Gene ID: 4609

Pathways: p53 Signaling, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect