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Aurora A antibody
AURKA
Reactivity: Human, Mouse, Rat
WB, IF, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Aurora A Antibody
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Target
See all Aurora A (AURKA) Antibodies
Aurora A (AURKA)
(Aurora Kinase A (AURKA))
Reactivity
All reactivities for Aurora A antibodies
Human, Mouse, Rat
Host
All hosts for Aurora A antibodies
Rabbit
Clonality
All clonalities for Aurora A antibodies
Polyclonal
Conjugate
All conjugates for Aurora A antibodies
This Aurora A antibody is un-conjugated
Application
All applications for Aurora A antibodies
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody detects endogenous levels of AurA protein. (region surrounding Tyr338)
Cross-Reactivity (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Purity
> 95 % pure by SDS-PAGE
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Discover our top product AURKA Primary Antibody
Alternatives
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Application Details
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Application Notes
ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
DO NOT FREEZE!
Storage
4 °C
Storage Comment
Store the antibody undiluted at 2-8 °C.
Target Details for Aurora A
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Target
Aurora A (AURKA)
(Aurora Kinase A (AURKA))
Alternative Name
Aurora Kinase A (AURKA Products )
Synonyms
AIK antibody, ARK1 antibody, AURA antibody, AURORA2 antibody, BTAK antibody, PPP1R47 antibody, STK15 antibody, STK6 antibody, STK7 antibody, AIRK1 antibody, AU019385 antibody, AW539821 antibody, Ark1 antibody, Aurora-A antibody, Ayk1 antibody, IAK antibody, IAK1 antibody, Stk6 antibody, 87A7-9/2 antibody, Aur-A antibody, AurA antibody, CG3068 antibody, Dmel\\CG3068 antibody, aur-A antibody, aurA antibody, ck10 antibody, ck[10] antibody, l(3)87Ac antibody, l(3)ck10 antibody, ARK-1 antibody, Eg2 antibody, aik antibody, ark1 antibody, aur-a antibody, aura antibody, aurka-a antibody, aurora2 antibody, btak antibody, stk15 antibody, stk6 antibody, stk7 antibody, pEg2 antibody, wu:fb37c10 antibody, wu:fc02c02 antibody, zgc:100912 antibody, AURKA antibody, aurka antibody, aurora kinase A antibody, aurora A antibody, aurora kinase A L homeolog antibody, hypothetical protein antibody, aurora kinase A S homeolog antibody, AURKA antibody, Aurka antibody, aurA antibody, aurka.L antibody, aurka antibody, Aurora-A antibody, aurka.S antibody
Background
Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.Synonyms: AIK1, ARK1, AURA, AURKA, AURORA2, Aurora/IPL1-related kinase 1, BTAK, Breast tumor-amplified kinase, STK15, STK6, Serine/threonine kinase 15, Serine/threonine-protein kinase 6
Molecular Weight
approx. 46 kDa
Gene ID
6790
NCBI Accession
NP_003591
UniProt
O14965
Pathways
Cell Division Cycle , Asymmetric Protein Localization
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