SERPINB5 antibody (Middle Region)
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- Target See all SERPINB5 Antibodies
- SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Dog, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SERPINB5 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRLNKT DTKPVQMMNM
- Predicted Reactivity
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 93%, Mouse: 86%, Rabbit: 86%, Rat: 93%
- Characteristics
- This is a rabbit polyclonal antibody against SERPINB5. It was validated on Western Blot and immunohistochemistry.
- Purification
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SERPINB5
- Top Product
- Discover our top product SERPINB5 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 375 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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SERPINB5 Promoter Hypomethylation Differentiates Pancreatic Ductal Adenocarcinoma From Pancreatitis." in: Pancreas, Vol. 45, Issue 5, pp. 743-7, (2016) (PubMed).
: "Cancer cell resistance to aurora kinase inhibitors: identification of novel targets for cancer therapy." in: Journal of proteome research, Vol. 12, Issue 1, pp. 455-69, (2013) (PubMed).
: "SERPINB5 and AKAP12 - expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma." in: BMC cancer, Vol. 10, pp. 549, (2010) (PubMed).
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SERPINB5 Promoter Hypomethylation Differentiates Pancreatic Ductal Adenocarcinoma From Pancreatitis." in: Pancreas, Vol. 45, Issue 5, pp. 743-7, (2016) (PubMed).
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- Target
- SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))
- Alternative Name
- SERPINB5 (SERPINB5 Products)
- Synonyms
- 1110036M19Rik antibody, AI462524 antibody, AI646751 antibody, Maspin antibody, PI-5 antibody, Spi7 antibody, ovalbumin antibody, PI5 antibody, maspin antibody, Pi5 antibody, serine (or cysteine) peptidase inhibitor, clade B, member 5 antibody, serpin family B member 5 antibody, serpin peptidase inhibitor, clade B (ovalbumin), member 5 S homeolog antibody, Serpinb5 antibody, SERPINB5 antibody, serpinb5.S antibody
- Background
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As a tumor suppressor, it blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Alias Symbols: PI5, maspin
Protein Interaction Partner: SUMO2, WWOX, FBXO32, KHDRBS3, ISG15, UBC, Cdk1, UCHL5, HDAC1,
Protein Size: 375 - Molecular Weight
- 41 kDa
- Gene ID
- 5268
- NCBI Accession
- NM_002639, NP_002630
- UniProt
- P36952
- Pathways
- p53 Signaling
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