CRHR2 antibody (N-Term)
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- Target See all CRHR2 Antibodies
- CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))
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Binding Specificity
- N-Term
- Reactivity
- Human, Mouse, Rat, Cow, Dog, Rabbit, Horse, Guinea Pig, Sheep, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CRHR2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- NTTLDQIGTC WPRSAAGALV ERPCPEYFNG VKYNTTRNAY RECLENGTWA
- Predicted Reactivity
- Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Sheep: 75%, Zebrafish: 93%
- Characteristics
- This is a rabbit polyclonal antibody against CRHR2. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product CRHR2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 438 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CRHR2 (Corticotropin Releasing Hormone Receptor 2 (CRHR2))
- Alternative Name
- CRHR2 (CRHR2 Products)
- Synonyms
- CRF-RB antibody, CRF2 antibody, CRFR2 antibody, HM-CRF antibody, CRF-R2 antibody, CRFR2alpha antibody, CRFR2beta antibody, Crfr2 antibody, Crf2r antibody, CRH-R2 antibody, crhr2-A antibody, corticotropin releasing hormone receptor 2 antibody, corticotropin releasing hormone receptor 2 S homeolog antibody, CRHR2 antibody, Crhr2 antibody, crhr2.S antibody
- Background
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The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis.
Alias Symbols: CRFR2, CRF2, CRF-RB, HM-CRF
Protein Interaction Partner: APP, UCN2, UCN3, CRH, CRHR2, UCN,
Protein Size: 438 - Molecular Weight
- 48 kDa
- Gene ID
- 1395
- NCBI Accession
- NM_001202475, NP_001189404
- UniProt
- Q13324
- Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Feeding Behaviour
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