Caspase 4 antibody (AA 118-132)

Catalog No. ABIN292685

Product Details anti-Caspase 4 Antibody

Target: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Binding Specificity: AA 118-132

Reactivity: Human, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This Caspase 4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Specificity: Human CASP4 / Caspase 4. This antibody is expected to recognise both isoforms of CASP4 (alpha, represented by NP_001216.1 and gamma, NP_150649.1).

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Bovine, Cat (87%) Marmoset, Dog, Horse (80%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide CKERAEEIYPIKERN from an internal region of human CASP4 / Caspase 4 (NP_001216.1, NP_150649.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%), Bovine, Cat (87%), Marmoset, Dog, Horse (80%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: Peptide-ELISA (1:16000), WB (1:16000, 0.3 - 2 μg/mL)

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Caspase 4

Target: Caspase 4 (CASP4) (Caspase 4, Apoptosis-Related Cysteine Peptidase (CASP4))

Alternative Name: CASP4 / Caspase 4 (CASP4 Products)

Synonyms: ICE(rel)II antibody, ICEREL-II antibody, ICH-2 antibody, Mih1/TX antibody, TX antibody, Casp11 antibody, CASP13 antibody, CASP1 antibody, CASP4 antibody, Caspl antibody, ich-3 antibody, Casp4 antibody, caspase 4 antibody, caspase 4, apoptosis-related cysteine peptidase antibody, caspase-4 antibody, CASP4 antibody, Casp4 antibody, LOC100731032 antibody

Background: Name/Gene ID: CASP4
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP4, CASP-4, Casp11, Caspase 4, Caspase-4, Cysteine protease icerel-ii, ICE(rel)-II, ICE(rel)II, ICH-2, Ich-3, ICH2, Protease ICH-2, TX, Tx protease, Caspase 11, ICEREL-II, Mih1/TX, Protease TX

Gene ID: 837

NCBI Accession: NP_001216, NP_150649

UniProt: P49662

Pathways: Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity