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KCNQ1 antibody (AA 250-549)
KCNQ1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-KCNQ1 Antibody
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Target
See all KCNQ1 Antibodies
KCNQ1
(Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))
Binding Specificity
All epitopes for KCNQ1 antibodies
AA 250-549
Reactivity
All reactivities for KCNQ1 antibodies
Human
Host
All hosts for KCNQ1 antibodies
Rabbit
Clonality
All clonalities for KCNQ1 antibodies
Polyclonal
Conjugate
All conjugates for KCNQ1 antibodies
This KCNQ1 antibody is un-conjugated
Application
All applications for KCNQ1 antibodies
Western Blotting (WB)
Sequence
TAWRCYAAEN PDSSTWKIYI RKAPRSHTLL SPSPKPKKSV VVKKKKFKLD KDNGVTPGEK MLTVPHITCD PPEERRLDHF SVDGYDSSVR KSPTLLEVSM PHFMRTNSFA EDLDLEGETL LTPITHISQL REHHRATIKV IRRMQYFVAK KKFQQARKPY DVRDVIEQYS QGHLNLMVRI KELQRRLDQS IGKPSLFISV SEKSKDRGSN TIGARLNRVE DKVTQLDQRL ALITDMLHQL LSLHGGSTPG SGGPPREGGA HITQPCGSGG SVDPELFLPS NTLPTYEQLT VPRRGPDEGS
Cross-Reactivity
Human, Mouse, Rat
Characteristics
Polyclonal Antibodies
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 250-549 of human KCNQ1 (NP_861463.1).
Isotype
IgG
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Discover our top product KCNQ1 Primary Antibody
Alternatives
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Application Details
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Application Notes
WB,1:500 - 1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid freeze / thaw cycles
Storage
-20 °C
Storage Comment
Store at -20°C. Avoid freeze / thaw cycles.
Target Details for KCNQ1
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Target
KCNQ1
(Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))
Alternative Name
KCNQ1 (KCNQ1 Products )
Synonyms
ATFB1 antibody, ATFB3 antibody, JLNS1 antibody, KCNA8 antibody, KCNA9 antibody, KVLQT1 antibody, Kv1.9 antibody, Kv7.1 antibody, LQT antibody, LQT1 antibody, RWS antibody, SQT2 antibody, WRS antibody, CG12215 antibody, CG12915 antibody, CG33135 antibody, DKCNQ antibody, Dmel\\CG33135 antibody, dKCNQ antibody, kcnq1 antibody, KCNQ1 antibody, kqt-3 antibody, kv7.1 antibody, Kvlqt1 antibody, KvLQT-1 antibody, kcnq1-A antibody, xkvlqt1 antibody, zgc:158384 antibody, AW559127 antibody, Kcna9 antibody, KvLQT1 antibody, potassium voltage-gated channel subfamily Q member 1 antibody, KCNQ potassium channel antibody, potassium voltage-gated channel, KQT-like subfamily, member 1 antibody, potassium channel, voltage gated KQT-like subfamily Q, member 1 antibody, voltage gated potassium channel subunit antibody, potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog antibody, potassium voltage-gated channel, subfamily Q, member 1 antibody, KCNQ1 antibody, KCNQ antibody, kcnq1 antibody, Kcnq1 antibody, kcnq1.L antibody
Background
This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.,KCNQ1,ATFB1,ATFB3,JLNS1,KCNA8,KCNA9,KVLQT1,Kv1.9,Kv7.1,LQT,LQT1,RWS,SQT2,WRS,Signal Transduction,Endocrine & Metabolism,Neuroscience,Cardiovascular,Heart,Cardiac arrhythmias,KCNQ1
Molecular Weight
61 kDa/74 kDa
Gene ID
3784
UniProt
P51787
Pathways
Negative Regulation of Hormone Secretion , Sensory Perception of Sound
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