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KCNQ1 antibody (AA 250-549)

KCNQ1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN3023121
  • Target See all KCNQ1 Antibodies
    KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))
    Binding Specificity
    • 15
    • 12
    • 11
    • 8
    • 7
    • 7
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 250-549
    Reactivity
    • 59
    • 35
    • 27
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 58
    • 15
    • 1
    • 1
    Rabbit
    Clonality
    • 60
    • 15
    Polyclonal
    Conjugate
    • 30
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KCNQ1 antibody is un-conjugated
    Application
    • 67
    • 27
    • 19
    • 14
    • 13
    • 13
    • 13
    • 13
    • 10
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    TAWRCYAAEN PDSSTWKIYI RKAPRSHTLL SPSPKPKKSV VVKKKKFKLD KDNGVTPGEK MLTVPHITCD PPEERRLDHF SVDGYDSSVR KSPTLLEVSM PHFMRTNSFA EDLDLEGETL LTPITHISQL REHHRATIKV IRRMQYFVAK KKFQQARKPY DVRDVIEQYS QGHLNLMVRI KELQRRLDQS IGKPSLFISV SEKSKDRGSN TIGARLNRVE DKVTQLDQRL ALITDMLHQL LSLHGGSTPG SGGPPREGGA HITQPCGSGG SVDPELFLPS NTLPTYEQLT VPRRGPDEGS
    Cross-Reactivity
    Human, Mouse, Rat
    Characteristics
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 250-549 of human KCNQ1 (NP_861463.1).
    Isotype
    IgG
    Top Product
    Discover our top product KCNQ1 Primary Antibody
  • Application Notes
    WB,1:500 - 1:2000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid freeze / thaw cycles
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))
    Alternative Name
    KCNQ1 (KCNQ1 Products)
    Synonyms
    ATFB1 antibody, ATFB3 antibody, JLNS1 antibody, KCNA8 antibody, KCNA9 antibody, KVLQT1 antibody, Kv1.9 antibody, Kv7.1 antibody, LQT antibody, LQT1 antibody, RWS antibody, SQT2 antibody, WRS antibody, CG12215 antibody, CG12915 antibody, CG33135 antibody, DKCNQ antibody, Dmel\\CG33135 antibody, dKCNQ antibody, kcnq1 antibody, KCNQ1 antibody, kqt-3 antibody, kv7.1 antibody, Kvlqt1 antibody, KvLQT-1 antibody, kcnq1-A antibody, xkvlqt1 antibody, zgc:158384 antibody, AW559127 antibody, Kcna9 antibody, KvLQT1 antibody, potassium voltage-gated channel subfamily Q member 1 antibody, KCNQ potassium channel antibody, potassium voltage-gated channel, KQT-like subfamily, member 1 antibody, potassium channel, voltage gated KQT-like subfamily Q, member 1 antibody, voltage gated potassium channel subunit antibody, potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog antibody, potassium voltage-gated channel, subfamily Q, member 1 antibody, KCNQ1 antibody, KCNQ antibody, kcnq1 antibody, Kcnq1 antibody, kcnq1.L antibody
    Background
    This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.,KCNQ1,ATFB1,ATFB3,JLNS1,KCNA8,KCNA9,KVLQT1,Kv1.9,Kv7.1,LQT,LQT1,RWS,SQT2,WRS,Signal Transduction,Endocrine & Metabolism,Neuroscience,Cardiovascular,Heart,Cardiac arrhythmias,KCNQ1
    Molecular Weight
    61 kDa/74 kDa
    Gene ID
    3784
    UniProt
    P51787
    Pathways
    Negative Regulation of Hormone Secretion, Sensory Perception of Sound
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