TFAP2A antibody (AA 1-166)

Catalog No. ABIN3029198

Product Details anti-TFAP2A Antibody

Target: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Binding Specificity: AA 1-166

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFAP2A antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogen: Human partial recombinant protein (AA 1-166) was used as the immunogen for this AP2 alpha antibody.

Isotype: IgG

Application Details

Application Notes: The stated application concentrations are suggested starting amounts. Titration of the AP2 alpha antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Handling

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: After reconstitution, the AP2 alpha antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Target Details for TFAP2A

Target: TFAP2A (Transcription Factor AP-2 alpha (Activating Enhancer Binding Protein 2 Alpha) (TFAP2A))

Alternative Name: AP2 alpha (TFAP2A Products)

Synonyms: TFAP2A antibody, Ap-2 antibody, AP-2 antibody, AP-2alpha antibody, AP2TF antibody, BOFS antibody, TFAP2 antibody, ap2 antibody, xap2 antibody, XAP-2 antibody, ap2tf antibody, tfap2 antibody, ap-2alpha antibody, tfap2alpha antibody, cb93 antibody, fb83f04 antibody, fc31a07 antibody, wu:fb83f04 antibody, wu:fc31a07 antibody, tfap2a-a antibody, tcfap2a antibody, ap2a antibody, AP2alpha antibody, Ap2 antibody, Ap2tf antibody, Tcfap2a antibody, AP2 antibody, transcription factor AP-2 alpha antibody, transcription factor AP-2 antibody, tto transcription factor AP-2 alpha antibody, to transcription factor AP-2 alpha L homeolog antibody, to transcription factor AP-2 alpha S homeolog antibody, Transcription factor AP-2 alpha antibody, transcription factor AP-2, alpha antibody, TFAP2A antibody, LOC100302602 antibody, tfap2a antibody, tfap2a.L antibody, tfap2a.S antibody, ap2a antibody, Tfap2a antibody

Background: AP2 alpha, or BOFS, is a protein that in humans is encoded by the TFAP2A gene. It is a transcription factor that binds the consensus sequence 5'-GCCNNNGGC-3'. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. TFAP2A acts as a sequence-specific DNA-binding transcription factor recognizing and binding to the specific DNA sequence and recruiting transcription machinery. This gene is expressed in neural crest cell lineages with the highest levels of expression corresponding to early neural crest cells, suggesting that TFAP2A plays a role in their differentiation and development.

Gene ID: 7020

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Response to Water Deprivation, Sensory Perception of Sound, Tube Formation, Embryonic Body Morphogenesis, Brown Fat Cell Differentiation, Lipid Metabolism